Výsledky vyhledávání - "Kumiko Shimozawa"

Gene Expression Profile of Dorsal Root Ganglion in a Lumbar Radiculopathy Model

Autor: Tsuneo Takebayashi, Satoshi Mizuno, Hirohito Takeuchi, Toshihiko Torigoe, Takashi Kirita, Toshihiko Yamashita, Kumiko Shimozawa, Noriyuki Sato, Satoshi Kawaguchi

Publikováno v: Spine. 33:2483-2488

Study Design. DNA array analysis of dorsal root ganglion (DRG) using a rat model with nerve root constriction. Objective. To determine the molecular changes in the DRG adjacent to the injured nerve root in a lumbar radiculopathy model. Summary of Bac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23240bc76b4cfc7fadb19064b7312075
https://doi.org/10.1097/brs.0b013e318184acc3

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Prognostic significance of HLA class I expression in osteosarcoma defined by anti-pan HLA class I monoclonal antibody, EMR8-5

Autor: Shigeharu Kimura, Yuki Nabeta, Satoshi Kawaguchi, Kumiko Shimozawa, Satoshi Nagoya, Takuro Wada, Toshihiko Torigoe, Noriyuki Sato, Toshihiko Yamashita, Emiri Nakazawa, Tomohide Tsukahara, Mitsunori Kaya, Hiroko Asanuma

Publikováno v: Cancer Science. 97:1374-1380

With the goal of establishing efficacious peptide-based immunotherapy for patients with bone and soft tissue sarcomas, we previously identified the cytotoxic T lymphocyte-defined osteosarcoma antigenic gene Papillomavirus binding factor. The present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1baa15ab8e7f98662bf1286c71eb4a60
https://doi.org/10.1111/j.1349-7006.2006.00317.x

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Expression and antigenicity of survivin, an inhibitor of apoptosis family member, in bladder cancer: Implications for specific immunotherapy

Autor: Hiroshi Kitamura, Kumiko Shimozawa, Yoshihiko Hirohashi, Eiji Sato, Toshihiko Torigoe, Emiri Nakazawa, Hiroko Asanuma, Taiji Tsukamoto, Noriyuki Sato, Ichiya Honma

Publikováno v: Urology. 67:955-959

Objectives To assess the expression of survivin in transitional cell carcinoma of the bladder and to study whether survivin is a transitional cell carcinoma-specific antigen that could be a target for immunotherapy. Survivin, an inhibitor of apoptosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2452e4018ec5341397aa58e86fb1e064
https://doi.org/10.1016/j.urology.2005.11.052

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Identification of Human Autologous Cytotoxic T-Lymphocyte-Defined Osteosarcoma Gene That Encodes a Transcriptional Regulator, Papillomavirus Binding Factor

Autor: Tomohide Tsukahara, Toshihiko Torigoe, Kazunori Ida, Hiroaki Hiraga, Yoshihiko Hirohashi, Toshihiko Yamashita, Yuriko Sato, Yuki Nabeta, Kumiko Shimozawa, Takuro Wada, Hideyuki Ikeda, Satoshi Kawaguchi, Hiroko Asanuma, Noriyuki Sato, Satoshi Nagoya

Publikováno v: Cancer Research. 64:5442-5448

The prognosis for patients with osteosarcoma who do not respond to current chemotherapy protocols still remains poor. Toward the goal of establishing efficacious peptide-based immunotherapy for those patients, we previously developed an autologous pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91aa659fa9a14784bf6e44ca8ade5ebe
https://doi.org/10.1158/0008-5472.can-04-0522

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Cytotoxic constituents in the holdfast of cultivated Laminaria japonica

Autor: Takako Aoyama, Kumiko Shimozawa, Yukari Noguchi, Kouichi Jinbow, Hideo Bando, Kiyoshi Horita, Makoto Nishizawa, Nobuaki Takahashi, Takashi Yamagishi

Publikováno v: Fisheries Science. 69:639-643

Four steroidal ketones were isolated from the holdfast of cultivated Laminaria japonica. The structures were characterized as ergosta-4,24(28)-diene-3-one (1), ergosta-4,24(28)-diene-3,6-dione (2), stigmasta-4,24(28)-diene-3-one (3) and stigmasta-4,2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9261b1d16d68227638b9b8ab1d7f8b70
https://doi.org/10.1046/j.1444-2906.2003.00667.x

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Anti-tumor Effect of Chemically Synthesized Sulfolipids Based on Sea Urchin's Natural Sulfonoquinovosylmonoacylglycerols

Autor: Nobuaki Takahashi, Masako Ishikawa, Shinya Hanashima, Hiroeki Sahara, Kengo Sakaguchi, Yoshiyuki Mizushina, K Jimbow, Noriyuki Sato, Fumio Sugawara, Kumiko Shimozawa, Shunya Takahashi, Keisuke Ohta, Takayuki Yamazaki, Shinsei Gasa, Seiji Ohtani

Publikováno v: Japanese Journal of Cancer Research : Gann

We recently reported that 3'-sulfonoquinovosyl-1'-monoacylglycerol (designated A-5) extracted from sea urchin intestine was effective in suppressing the growth of solid tumors. Although the major fatty acid component of A-5 was a saturated C(16) acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9331211b532433e0dc1250766ef18d76
https://doi.org/10.1111/j.1349-7006.2002.tb01204.x

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Clinical and immunological evaluation of anti-apoptosis protein, survivin-derived peptide vaccine in phase I clinical study for patients with advanced or recurrent breast cancer

Autor: Yasuhiro Mizushima, Tosei Ohmura, Atsuhito Yagihashi, Koichi Hirata, Koji Yamaguchi, Tadashi Katsuramaki, Yasutoshi Kimura, Hiroko Asanuma, Nobuhiko Toyota, Yoshihiko Hirohashi, Tomohisa Furuhata, Kumiko Shimozawa, Yuji Iwayama, Naohiro Nomura, Tetsuhiro Tsuruma, Fumitake Hata, Noriyuki Sato, Toshihiko Torigoe, Minoru Okazaki

Publikováno v: Journal of Translational Medicine
Journal of Translational Medicine, Vol 6, Iss 1, p 24 (2008)

Background We previously reported that survivin-2B, a splicing variant of survivin, was expressed in various types of tumors and that survivin-2B peptide might serve as a potent immunogenic cancer vaccine. The objective of this study was to examine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e438d8cddc3d31be040efa96ec9bee
https://doi.org/10.1186/1479-5876-6-24

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Phase I vaccination trial of SYT-SSX junction peptide in patients with disseminated synovial sarcoma

Autor: Satoshi, Kawaguchi, Takuro, Wada, Kazunori, Ida, Yuriko, Sato, Satoshi, Nagoya, Tomohide, Tsukahara, Sigeharu, Kimura, Hiroeki, Sahara, Hideyuki, Ikeda, Kumiko, Shimozawa, Hiroko, Asanuma, Toshihiko, Torigoe, Hiroaki, Hiraga, Takeshi, Ishii, Shin-Ichiro, Tatezaki, Noriyuki, Sato, Toshihiko, Yamashita

Publikováno v: Journal of Translational Medicine, Vol 3, Iss 1, p 1 (2005)
Journal of Translational Medicine

Background Synovial sarcoma is a high-grade malignant tumor of soft tissue, characterized by the specific chromosomal translocation t(X;18), and its resultant SYT-SSX fusion gene. Despite intensive multimodality therapy, the majority of metastatic or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d511c2c3d39aa3c28a27dd62cc0edfdf
http://www.translational-medicine.com/content/3/1/1

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An immunosuppressive effect by synthetic sulfonolipids deduced from sulfonoquinovosyl diacylglycerols of sea urchin

Autor: Toshihiko Torigoe, Kengo Sakaguchi, Shunya Takahashi, Takeyuki Yamazaki, Keisuke Ohta, Hiroeki Sahara, Tatsuya Fujita, Kumiko Shimozawa, Nobuaki Takahashi, Fumio Sugawara, Shinya Hanashima, K Jimbow, Mika Takenouchi, Shinsei Gasa, Noriyuki Sato, Yoshitaka Matsumoto, Yoshiyuki Mizushina

Publikováno v: Transplantation. 74(2)

BACKGROUND It is important to develop new immunosuppressive agents without clinical drawbacks. In this article, we reveal the possibility of a chemically synthetic sulfonolipid that acts as a novel immunosuppressive drug. METHODS We evaluated the imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbf9d02bdf978314d2271835385d627
https://pubmed.ncbi.nlm.nih.gov/12151740

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