Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Kumiko Sakata‐Sogawa"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract The dynamic properties of molecules in living cells are attracting increasing interest. We propose a new method, moving subtrajectory analysis using single-molecule tracking, and demonstrate its utility in the spatiotemporal quantification o
Externí odkaz:
https://doaj.org/article/34e1478115ed46ee9c70b10cff6b814d
Autor:
Ana V Miletic, Daniel B Graham, Kumiko Sakata-Sogawa, Michio Hiroshima, Michael J Hamann, Saso Cemerski, Tracie Kloeppel, Daniel D Billadeau, Osami Kanagawa, Makio Tokunaga, Wojciech Swat
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6599 (2009)
BACKGROUND:T cell receptor (TCR) engagement leads to formation of signaling microclusters and induction of rapid and dynamic changes in the actin cytoskeleton, although the exact mechanism by which the TCR initiates actin polymerization is incomplete
Externí odkaz:
https://doaj.org/article/531bd18f9d744b3db2490e47f9786ecb
Autor:
Haruka Matsumori, Kenji Watanabe, Hiroaki Tachiwana, Tomoko Fujita, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa, Hiroko Osakada, Tokuko Haraguchi, Akinori Awazu, Hiroshi Ochiai, Yuka Sakata, Koji Ochiai, Tsutomu Toki, Etsuro Ito, Ilya G Goldberg, Kazuaki Tokunaga, Mitsuyoshi Nakao, Noriko Saitoh
Publikováno v:
Life science alliance. 5(7)
The nucleolus is the site of ribosome assembly and formed through liquid–liquid phase separation. Multiple ribosomal DNA (rDNA) arrays are bundled in the nucleolus, but the underlying mechanism and significance are unknown. In the present study, we
Autor:
Haruka Matsumori, Kenji Watanabe, Hiroaki Tachiwana, Tomoko Fujita, Yuma Ito, Makio Tokunaga, Kumiko Sakata-Sogawa, Hiroko Osakada, Tokuko Haraguchi, Akinori Awazu, Hiroshi Ochiai, Yuka Sakata, Koji Ochiai, Tsutomu Toki, Etsuro Ito, Goldberg, Ilya G., Kazuaki Tokunaga, Mitsuyoshi Nakao, Noriko Saitoh
Publikováno v:
Life Science Alliance; Jul2022, Vol. 5 Issue 7, p1-18, 18p
Autor:
Kumiko Sakata-Sogawa, Yuma Ito, Tomo Saito, Kazuhiro Sogawa, Hiroshi Fukumura, Ken Ichi Yasumoto, Makio Tokunaga, Shinji Kajimoto, Shuya Kasai
Publikováno v:
Journal of Biochemistry. 161(No. 3):291-296
Inhibitory PAS domain protein (IPAS) is a dual function protein acting as a transcriptional repressor and as a pro-apoptotic protein. Simultaneous dual-color single-molecule imaging of EGFP-IPAS coexpressed with Mit-TagRFP-T in living HeLa cells reve
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
The microtubule-organizing centre (MTOC) is repositioned to the centre of the contacted cell surface, the immunological synapse, during T cell activation. However, our understanding of its molecular mechanism remains limited. Here, we found that the
Publikováno v:
Biosci Biotechnol Biochem. 79(No. 2):242-246
RNA microarray analyses revealed that nuclear actin activated many human transcription factor genes including OCT4, which is required for gene reprogramming. Oct4 is known to be activated by nuclear actin in Xenopus oocytes. Our findings imply that t
Autor:
Hiroshi Kimura, Kazumitsu Maehara, Naohito Nozaki, Yoko Hayashi-Takanaka, Takahiro Nagase, Yasuyuki Ohkawa, James G. McNally, Timothy J. Stasevich, Kumiko Sakata-Sogawa, Yuko Sato, Makio Tokunaga
Publikováno v:
Nature. 516:272-275
In eukaryotic cells, post-translational histone modifications have an important role in gene regulation. Starting with early work on histone acetylation, a variety of residue-specific modifications have now been linked to RNA polymerase II (RNAP2) ac
Autor:
Masaaki Iwamoto, Haruhiko Asakawa, Takaharu G. Yamamoto, Makio Tokunaga, Yasushi Hiraoka, Tokuko Haraguchi, Hui-Ju Yang, Chizuru Ohtsuki, Kumiko Sakata-Sogawa, Yuji Chikashige
Publikováno v:
Nucleus
The nuclear pore complex (NPC) is an enormous proteinaceous complex composed of multiple copies of about 30 different proteins called nucleoporins. In this study, we analyzed the composition of the NPC in the model organism Schizosaccharomyces pombe
Autor:
Kumiko Sakata-Sogawa, Makio Tokunaga
Publikováno v:
Seibutsu Butsuri. 49:318-321