Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Kumiko Ogawa"'
Autor:
Yuchen Sun, Kosuke Saito, Atsuhito Ushiki, Mitsuhiro Abe, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Kazuhisa Takemoto, Rika Ishikawa, Toshiko Momiyama, Shin-ichiro Matsuyama, Noriaki Arakawa, Hirotoshi Akane, Takeshi Toyoda, Kumiko Ogawa, Motonobu Sato, Kazuhiko Takamatsu, Kazuhiko Mori, Takayoshi Nishiya, Takashi Izumi, Yasuo Ohno, Yoshiro Saito, Masayuki Hanaoka
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background Drug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical practice and drug development. Clinical management of the condition would be improved if the
Externí odkaz:
https://doaj.org/article/1318948710974ad7a181c0d83d189e4d
Autor:
Todd Bourcier, Timothy McGovern, Tania Cavaliero, Geoffrey Ebere, Akiyoshi Nishikawa, Jihei Nishimura, Kumiko Ogawa, Markku Pasanen, Alisa Vespa, Jan Willem Van der Laan
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Introduction: The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) initiated a process in 2012 to revise the S1B Guideline “Testing for Carcinogenicity of Pharmaceuticals”. Previous retrosp
Externí odkaz:
https://doaj.org/article/33fbb9510add4dbf852e75ae21296a20
Publikováno v:
Particle and Fibre Toxicology, Vol 20, Iss 1, Pp 1-23 (2023)
Abstract Background Though titanium dioxide (TiO2) is generally considered to have a low impact in the human body, the safety of TiO2 containing nanosized particles (NPs) has attracted attention. We found that the toxicity of silver NPs markedly vari
Externí odkaz:
https://doaj.org/article/64881a9e93f94414ac44712639c1c65e
Autor:
Noriaki Arakawa, Atsuhito Ushiki, Mitsuhiro Abe, Shinichiro Matsuyama, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Keiko Miyashita, Kosuke Saito, Ryosuke Nakamura, Takeshi Toyoda, Kumiko Ogawa, Motonobu Sato, Kazuhiko Takamatsu, Kazuhiko Mori, Takayoshi Nishiya, Takashi Izumi, Yasuo Ohno, Yoshiro Saito, Masayuki Hanaoka
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
No reliable serum biomarker for diffuse alveolar damage, a poor prognosis subtype of drug-induced interstitial lung disease, is currently available. Here, the authors show stratifin/14-3-3σ in serum is a promising biomarker for diagnosis of this typ
Externí odkaz:
https://doaj.org/article/26c767ba6b984eb3ba31e8f03b45e8ce
Autor:
Kosuke Saito, Rika Ishikawa, Isao Kitamura, Kumiko Ogawa, Noriaki Arakawa, Yuchen Sun, Kazuo Imai, Takuya Maeda, Yoshiro Saito, Chihiro Hasegawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 2, Pp 49-55 (2022)
The coronavirus disease 2019 (COVID-19) pandemic has been associated with high mortality worldwide. Owing to its complicated pathophysiology, diagnostic and prognostic biomarkers for effective patient management remain scarce. We analyzed kynurenine,
Externí odkaz:
https://doaj.org/article/1a72e057b07643b1ac22799639a56ac4
Autor:
Noriaki Arakawa, Shinichiro Matsuyama, Masaru Matsuoka, Isao Kitamura, Keiko Miyashita, Yutaro Kitagawa, Kazuo Imai, Kumiko Ogawa, Takuya Maeda, Yoshiro Saito, Chihiro Hasegawa
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 1, Pp 21-30 (2022)
The prognosis of patients with severe cases of COVID-19 is poor; thus, biomarkers for earlier prediction of COVID-19 progression are vital. We measured levels of five lung injury-related biomarkers, SP-D, KL-6, presepsin, kallistatin and stratifin, i
Externí odkaz:
https://doaj.org/article/950290dd22614200abf2e6e6d3336397
Autor:
Manabu Yasui, Takayuki Fukuda, Akiko Ukai, Jiro Maniwa, Tadashi Imamura, Tsuneo Hashizume, Haruna Yamamoto, Kaori Shibuya, Kazunori Narumi, Yohei Fujiishi, Emiko Okada, Saori Fujishima, Mika Yamamoto, Naoko Otani, Maki Nakamura, Ryoichi Nishimura, Maya Ueda, Masayuki Mishima, Kaori Matsuzaki, Akira Takeiri, Kenji Tanaka, Yuki Okada, Munehiro Nakagawa, Shuichi Hamada, Akihiko Kajikawa, Hiroshi Honda, Jun Adachi, Kentaro Misaki, Kumiko Ogawa, Masamitsu Honma
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-19 (2021)
Abstract Background Conflicting results between bacterial mutagenicity tests (the Ames test) and mammalian carcinogenicity tests might be due to species differences in metabolism, genome structure, and DNA repair systems. Mutagenicity assays using hu
Externí odkaz:
https://doaj.org/article/28a26d2c8a28419a8e0d701873581be0
Publikováno v:
Genes and Environment, Vol 42, Iss 1, Pp 1-8 (2020)
Abstract Introduction Various challenges have been overcome with regard to applying ‘omics technologies for chemical risk assessments. Previously we published results detailing targeted mRNA sequencing (RNA-Seq) on a next generation sequencer using
Externí odkaz:
https://doaj.org/article/ad4abf07dcbb40319eb98e5f58261d32
Autor:
Takeshi Toyoda, Masami Yamamoto, Shinji Takasu, Kumiko Ogawa, Masae Tatematsu, Tetsuya Tsukamoto
Publikováno v:
Diseases, Vol 2, Iss 2, Pp 168-186 (2014)
Since the discovery of Helicobacter pylori (H. pylori), many efforts have been made to establish animal models for the investigation of the pathological features and molecular mechanisms of gastric carcinogenesis. Among the animal models, Mongolian g
Externí odkaz:
https://doaj.org/article/36c6863219d04eb0a7798931de336906
Autor:
Takeshi Toyoda1 t-toyoda@nihs.go.jp, Kumiko Ogawa1 ogawa93@nihs.go.jp
Publikováno v:
Journal of Toxicologic Pathology. 2022, Vol. 35 Issue 4, p283-298. 16p.