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pro vyhledávání: '"Kumiko I. Claycomb"'
Autor:
Stephen J. Crocker, Anthony V. Sacino, Kumiko I. Claycomb, Paige N. Winokur, Kasey M. Johnson
Publikováno v:
Brain Sciences, Vol 3, Iss 3, Pp 1109-1127 (2013)
Astrocytes regulate fundamentally important functions to maintain central nervous system (CNS) homeostasis. Altered astrocytic function is now recognized as a primary contributing factor to an increasing number of neurological diseases. In this revie
Externí odkaz:
https://doaj.org/article/aeaf2034092b4ffbb1064d0f19d43dcb
Autor:
Aurora Lopez-Rosas, Kumiko I. Claycomb, Maria I. Givogri, Richard B. van Breemen, Stephen J. Crocker, Maria Soledad Celej, Ludovico Cantuti-Castelvetri, Jose Ignacio Gallea, Marta B. Santos, Michael S. Marshall, Ernesto R. Bongarzone, Guannan Li, Benjamin Smith
Publikováno v:
The Journal of Pathology. 232:509-521
Demyelination is a major contributor to the general decay of neural functions in children with Krabbe disease. However, recent reports have indicated a significant involvement of neurons and axons in the neuropathology of the disease. In this study,
Publikováno v:
Journal of visualized experiments : JoVE. (92)
The precise function of multi-nucleated microglia, called globoid cells, that are uniquely abundant in the central nervous system of globoid cell leukodystrophy (GLD) is unclear. This gap in knowledge has been hindered by the lack of an appropriate i
Publikováno v:
Journal of Visualized Experiments.
The precise function of multi-nucleated microglia, called globoid cells, that are uniquely abundant in the central nervous system of globoid cell leukodystrophy (GLD) is unclear. This gap in knowledge has been hindered by the lack of an appropriate i
Autor:
Paige Winokur, Ernesto R. Bongarzone, Stephen J. Crocker, Kumiko I. Claycomb, Alexandra M. Nicaise, Kasey M. Johnson, Elisa Barbarese, Anthony Giampetruzzi, Evan Y. Snyder, Anthony V. Sacino
Globoid cell leukodystrophy (GLD), or Krabbe disease, is a rare and often fatal demyelinating disease caused by mutations in the galactocerebrosidase (galc) gene that result in accumulation of galactosylsphingosine (psychosine). We recently reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47a97d2adbf18c64981703a54aa84e6
https://europepmc.org/articles/PMC4169335/
https://europepmc.org/articles/PMC4169335/
Publikováno v:
Brain Sciences
Brain Sciences, Vol 3, Iss 3, Pp 1109-1127 (2013)
Brain Sciences, Vol 3, Iss 3, Pp 1109-1127 (2013)
Astrocytes regulate fundamentally important functions to maintain central nervous system (CNS) homeostasis. Altered astrocytic function is now recognized as a primary contributing factor to an increasing number of neurological diseases. In this revie