Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kumiko Higuchi"'
Autor:
Yoshikazu Haramoto, Yasuko Onuma, Shuuji Mawaribuchi, Yoshiro Nakajima, Yasuhiko Aiki, Kumiko Higuchi, Madoka Shimizu, Hiroaki Tateno, Jun Hirabayashi, Yuzuru Ito
Publikováno v:
Regenerative Therapy, Vol 14, Iss , Pp 306-314 (2020)
Introduction: Tumourigenesis attributed to residual undifferentiated cells in a graft is considered to be a significant issue in cell therapy using human pluripotent stem cells. To ensure the safety of regenerative medicine derived from pluripotent s
Externí odkaz:
https://doaj.org/article/f96df89f1fe7470286eb8cce3bbb1c39
Autor:
Yasuko Onuma, Kumiko Higuchi, Yasuhiko Aiki, Yujing Shu, Masahiro Asada, Makoto Asashima, Masashi Suzuki, Toru Imamura, Yuzuru Ito
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0118931 (2015)
Fibroblast growth factors (FGFs) are essential for maintaining self-renewal in human embryonic stem cells and induced pluripotent stem cells. Recombinant basic FGF (bFGF or FGF2) is conventionally used to culture pluripotent stem cells; however, beca
Externí odkaz:
https://doaj.org/article/53ab159043174091af94ef573311394a
Publikováno v:
Emerging Infectious Diseases, Vol 4, Iss 2, Pp 340-341 (1998)
Externí odkaz:
https://doaj.org/article/c533bc707e854a96bb34d58e6b309132
Autor:
Yasuhiko Aiki, Ayako Oyane, Maki Nakamura, Hiroko Araki, Alexander Pyatenko, Yuzuru Ito, Kumiko Higuchi, Adachi Masaki
Publikováno v:
RSC Advances. 10:95-104
Basic fibroblast growth factor (bFGF) is an essential supplement for culture media to support the proliferation of human pluripotent stem cells, while preserving their pluripotency. However, it is extremely unstable under cell culture conditions at 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2bf1ef716173561901f37564aae616
https://doi.org/10.1039/c9ra06906b
https://doi.org/10.1039/c9ra06906b
Autor:
Hiroshi Yamamura, Kumiko Higuchi, Yoshimasa Watanabe, Akira Hafuka, Qing Ding, Katsuki Kimura
Publikováno v:
Water Research. 87:218-224
While low-pressure membrane filtration processes (i.e., microfiltration and ultrafiltration) can offer precise filtration than sand filtration, they pose the problem of reduced efficiency due to membrane fouling. Although many studies have examined m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711fc7fad82b2d2f51bac3ee42e048e3
https://doi.org/10.1016/j.watres.2015.09.018
https://doi.org/10.1016/j.watres.2015.09.018
Autor:
Masahiro Asada, Yuzuru Ito, Makoto Asashima, Toru Imamura, Yujing Shu, Kumiko Higuchi, Masashi Suzuki, Yasuhiko Aiki, Yasuko Onuma
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0118931 (2015)
PLoS ONE, Vol 10, Iss 4, p e0118931 (2015)
Fibroblast growth factors (FGFs) are essential for maintaining self-renewal in human embryonic stem cells and induced pluripotent stem cells. Recombinant basic FGF (bFGF or FGF2) is conventionally used to culture pluripotent stem cells; however, beca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a162e110cb86b1440e6b337d6eb6240
http://europepmc.org/articles/PMC4388338
http://europepmc.org/articles/PMC4388338
Autor:
Hirokazu Fukuda, Etsuko Tanaka, Katsuhiko Nakashima, Hitoshi Nakagama, Naoto Tsuchiya, Kumiko Higuchi, Masato Katahira
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 598:120-131
Mammalian genomes contain several types of repetitive sequences. Some of these sequences are implicated in various specific cellular events, including meiotic recombination, chromosomal breaks and transcriptional regulation, and also in several human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5c09715ec1010978c59ff7d47abb27
https://doi.org/10.1016/j.mrfmmm.2006.01.014
https://doi.org/10.1016/j.mrfmmm.2006.01.014
Autor:
Masato Katahira, Minako Nagao, Hirokazu Fukuda, Naoto Tsuchiya, Kumiko Higuchi, Yoshiaki Enokizono, Etsuko Tanaka, Hitoshi Nakagama
Publikováno v:
Genes to Cells. 10:953-962
Fragile X syndrome is caused by expansion of a d(CGG) triplet repeat in the 5'-untranslated region of the first exon of the FMR1 gene resulting in silencing of the gene. The d(CGG) repeat has been reported to form hairpin and quadruplex structures in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21fd2b511bd30e0d45d4a88858ecf679
https://doi.org/10.1111/j.1365-2443.2005.00896.x
https://doi.org/10.1111/j.1365-2443.2005.00896.x
Autor:
Masumi Hidaka, Shigenori Iwai, Tsutomu Katayama, Takashi Horiuchi, Kumiko Higuchi, Hisaji Maki
Publikováno v:
Genes to Cells. 8:437-449
Background: The inhibition of DNA replication fork progression by DNA lesions can lead to cell death or genome instability. However, little is known about how such DNA lesions affect the concurrent synthesis of leading- and lagging-strand DNA catalys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29404b4b94dced5abd20fb1bd149e1fb
https://doi.org/10.1046/j.1365-2443.2003.00646.x
https://doi.org/10.1046/j.1365-2443.2003.00646.x
Autor:
Yasuhiko Aiki, Madoka Shimizu, Masaki Warashina, Masakazu Fukuda, Makoto Asashima, Susumu Honda, Keiko Hiemori, Yasuko Onuma, Jun Hirabayashi, Hiroaki Tateno, Yuzuru Ito, Kumiko Higuchi
Publikováno v:
Scientific Reports
While human pluripotent stem cells are attractive sources for cell-replacement therapies, a major concern remains regarding their tumorigenic potential. Thus, safety assessment of human pluripotent stem cell-based products in terms of tumorigenicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60176ead004e9ae4d8dacb7df8b07a8
http://europepmc.org/articles/PMC3921628
http://europepmc.org/articles/PMC3921628