Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kumiko Claycomb"'
Autor:
Lawrence S. Hsieh, John H. Wen, Kumiko Claycomb, Yuegao Huang, Felicia A. Harrsch, Janice R. Naegele, Fahmeed Hyder, Gordon F. Buchanan, Angelique Bordey
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
The etiology of focal cortical dysplasia (FCD) is not fully understood. Here authors generate an mTORC1 overactivation mouse model that recapitulates hallmarks of type II FCDs, including spontaneous seizures, and suggest that neuronal defects, rather
Externí odkaz:
https://doaj.org/article/f7ba5ffa0e6d426fa4bef37c114838b1
Autor:
Gordon F. Buchanan, Felicia A. Harrsch, Yuegao Huang, Lawrence S. Hsieh, Kumiko Claycomb, Fahmeed Hyder, John H. Wen, Angélique Bordey, Janice R. Naegele
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Focal cortical dysplasia (FCD), a local malformation of cortical development, is the most common cause of pharmacoresistant epilepsy associated with life-long neurocognitive impairments. It remains unclear whether neuronal misplacement is required fo