Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Kumiko, Samejima"'
Autor:
Lora Boteva, Ryu-Suke Nozawa, Catherine Naughton, Kumiko Samejima, William C. Earnshaw, Nick Gilbert
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108177- (2020)
Summary: Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer
Externí odkaz:
https://doaj.org/article/bd191e3aabbf4a60bf450f5a8d71b639
Autor:
Carlos Sacristan, Kumiko Samejima, Lorena Andrade Ruiz, Maaike L.A. Lambers, Adam Buckle, Chris A. Brackley, Daniel Robertson, Tetsuya Hori, Shaun Webb, Tatsuo Fukagawa, Nick Gilbert, Davide Marenduzzo, William C. Earnshaw, Geert J.P.L. Kops
The Structural Maintenance of Chromosomes (SMC) complexes cohesin and condensin establish the 3D organization of mitotic chromosomes1–3. Cohesin is essential to maintain sister chromatid pairing until anaphase onset4, while condensin is important f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42bbd9efc935406e689cfb25d5cefd80
https://doi.org/10.1101/2022.08.01.502248
https://doi.org/10.1101/2022.08.01.502248
Autor:
Laura Wood, Daniel G. Booth, Giulia Vargiu, Shinya Ohta, Flavia deLima Alves, Kumiko Samejima, Tatsuo Fukagawa, Juri Rappsilber, William C. Earnshaw
Publikováno v:
Open Biology, Vol 6, Iss 1 (2016)
Most studies using knockout technologies to examine protein function have relied either on shutting off transcription (conventional conditional knockouts with tetracycline-regulated gene expression or gene disruption) or destroying the mature mRNA (R
Externí odkaz:
https://doaj.org/article/97c69cff22474f879d7875d4a2279c55
Autor:
Daniel G Booth, Masatoshi Takagi, Luis Sanchez-Pulido, Elizabeth Petfalski, Giulia Vargiu, Kumiko Samejima, Naoko Imamoto, Chris P Ponting, David Tollervey, William C Earnshaw, Paola Vagnarelli
Publikováno v:
eLife, Vol 3 (2014)
When the nucleolus disassembles during open mitosis, many nucleolar proteins and RNAs associate with chromosomes, establishing a perichromosomal compartment coating the chromosome periphery. At present nothing is known about the function of this poor
Externí odkaz:
https://doaj.org/article/b63768057a194e75bbe34fafe5bca9fa
Autor:
Kumiko Samejima, Christos Spanos, Samejima I, Georg Kustatscher, Juri Rappsilber, William C. Earnshaw
Publikováno v:
Samejima, I, Spanos, C, Samejima, K, Rappsilber, J, Kustatscher, G & Earnshaw, W C 2022, ' Mapping the invisible chromatin transactions of prophase chromosome remodelling ', Molecular Cell, vol. 82, no. 3, pp. 696-708.E4 . https://doi.org/10.1016/j.molcel.2021.12.039
Samejima, I, Spanos, C, Samejima, K, Rappsilber, J, Kustatscher, G & Earnshaw, W C 2022, ' Mapping the invisible chromatin transactions of prophase chromosome remodeling ', Molecular Cell, vol. 82, no. 3, pp. 696-708.e4 . https://doi.org/10.1016/j.molcel.2021.12.039
Samejima, I, Spanos, C, Samejima, K, Rappsilber, J, Kustatscher, G & Earnshaw, W C 2022, ' Mapping the invisible chromatin transactions of prophase chromosome remodeling ', Molecular Cell, vol. 82, no. 3, pp. 696-708.e4 . https://doi.org/10.1016/j.molcel.2021.12.039
SUMMARYWe have used a combination of chemical genetics, chromatin proteomics and imaging to map the earliest chromatin transactions during vertebrate cell entry into mitosis. Chicken DT40 CDK1as cells undergo synchronous mitotic entry within 15 minut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6b91f29925b8a924603ca40190a2aa
https://doi.org/10.2139/ssrn.3882890
https://doi.org/10.2139/ssrn.3882890
Autor:
William C. Earnshaw, Lora Boteva, Catherine Naughton, Nick Gilbert, Kumiko Samejima, Ryu-Suke Nozawa
Publikováno v:
Boteva, L, Nozawa, R-S, Naughton, C, Samejima, K, Earnshaw, W C & Gilbert, N 2020, ' Common fragile sites are characterised by faulty condensin loading after replication stress ', Cell Reports . https://doi.org/10.1016/j.celrep.2020.108177
Cell Reports, Vol 32, Iss 12, Pp 108177-(2020)
Cell Reports
Cell Reports, Vol 32, Iss 12, Pp 108177-(2020)
Cell Reports
Summary Cells coordinate interphase-to-mitosis transition, but recurrent cytogenetic lesions appear at common fragile sites (CFSs), termed CFS expression, in a tissue-specific manner after replication stress, marking regions of instability in cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee6eb8929667617fcd0c9e39d5598657
https://www.pure.ed.ac.uk/ws/files/163714075/Common_fragile_sites_are_characterised_by_faulty_condensin_loading_after_replication_stress.pdf
https://www.pure.ed.ac.uk/ws/files/163714075/Common_fragile_sites_are_characterised_by_faulty_condensin_loading_after_replication_stress.pdf
Autor:
Karlene A. Cimprich, Linfeng Xie, Tobias Meyer, Mingyu Chung, David Cortez, James R. Paulson, Michael J. Bocek, Fernanda Cisneros-Soberanis, Thomas E. Bass, Stephan Hamperl, Kumiko Samejima, Joshua C. Saldivar, William C. Earnshaw
Publikováno v:
Science. 361:806-810
An additional cell cycle checkpoint Cell division is controlled by checkpoints that regulate the temporal order of the cell cycle phases, including the G 1 /S, G 2 /M, and metaphase/anaphase transitions. Yet there are no known control mechanisms for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f02406f586027fd93a7315839edd9b0
https://doi.org/10.1126/science.aap9346
https://doi.org/10.1126/science.aap9346
Autor:
Sandrine Ruchaud, Omid Feizbakhsh, Hiromi Ogawa, Xavier Fant, Bilge Askin, Nathalie Desban, William C. Earnshaw, Diana Papini, Kumiko Samejima, Tony Ly
Publikováno v:
Journal of Cell Science.
Timely and precise control of Aurora B kinase, the chromosomal passenger complex (CPC) catalytic subunit, is essential for accurate chromosome segregation and cytokinesis. Post-translational modifications of CPC subunits are directly involved in cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df29fc8099aeadac85543ec9f4719870
https://doi.org/10.1242/jcs.234401
https://doi.org/10.1242/jcs.234401
Publikováno v:
Current Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::cf9dd4c16fd6a25c932a0c6d63a0708c
Autor:
Michelle Peckham, Kumiko Samejima, Peter J. Knight, Giulia Vargiu, Melpomeni Platani, Hiromi Ogawa, Marcin Wolny, William C. Earnshaw
Publikováno v:
The Journal of Biological Chemistry
Samejima, K, Platani, M, Wolny, M, Ogawa, H, Vargiu, G, Knight, P J, Peckham, M & Earnshaw, W C 2015, ' The inner centromere protein (INCENP) coil is a single α-helix (SAH) domain that binds directly to microtubules and is important for chromosome passenger complex (CPC) localization and function in mitosis ', Journal of Biological Chemistry, vol. 290, no. 35, pp. 21460-21472 . https://doi.org/10.1074/jbc.M115.645317
Samejima, K, Platani, M, Wolny, M, Ogawa, H, Vargiu, G, Knight, P J, Peckham, M & Earnshaw, W C 2015, ' The inner centromere protein (INCENP) coil is a single α-helix (SAH) domain that binds directly to microtubules and is important for chromosome passenger complex (CPC) localization and function in mitosis ', Journal of Biological Chemistry, vol. 290, no. 35, pp. 21460-21472 . https://doi.org/10.1074/jbc.M115.645317
Background: INCENP is predicted to have a coiled coil domain. Results: The coil is actually a stable single α-helix (SAH) domain that is highly extendable and directly binds microtubules. Conclusion: This flexible dog leash may allow Aurora B to ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c2af8434834f86da7d0ea844fb3490
http://europepmc.org/articles/PMC4571873
http://europepmc.org/articles/PMC4571873