Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kumi Usuki"'
Autor:
Toshikiro Kimura, Yuji Kurosaki, Yasuyuki Matsuda, Toshio Suzuki, Takehiro Yamaguchi, Yukiko Fujiwara, Taiji Nakayama, Katsuo Unno, Kumi Usuki
Publikováno v:
Journal of Controlled Release. 30:125-135
Hydrophilic steriod derivatives, methyl 20-β-glucopyranosyloxyprednisolonates (15 and 16), were synthesizd from prenisolone via methyl 20( R/S )-dihydroprednisolonates (2 and 1) based on a novel colonic mucosa-specific drug delivery system. Optimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a0ca33ab36b73c4c3b2f6685d7990c7
https://doi.org/10.1016/0168-3659(94)90259-3
https://doi.org/10.1016/0168-3659(94)90259-3
Autor:
Katsuo Unno, Toshikiro Kimura, Yuji Kurosaki, Yukiko Fujiwara, Takehiro Yamaguchi, Kumi Usuki, Toshio Suzuki, Taiji Nakayama
Publikováno v:
Drug Delivery System. 6:375-379
The fate of 20 (R/S)-glucopyranosyloxy methyl-prednisolonates after the oral administration was examined in rats and guinea-pigs. The glycosides were stable in the small-intestinal contents, but the glycoside bonds were cleaved by the action of bacte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb77a8a4e6ed06d1d423d74afbd3aca0
https://doi.org/10.2745/dds.6.375
https://doi.org/10.2745/dds.6.375