Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Kumi Satoh"'
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Feline infectious peritonitis (FIP) is a life-threatening infectious disease of cats caused by virulent feline coronavirus (FIP virus: FIPV). For the treatment of FIP, several effective antivirals were recently reported, but many of these are not ava
Externí odkaz:
https://doaj.org/article/2723ca4f7fb84cb7a6fd783bd733d35a
Publikováno v:
Viruses, Vol 12, Iss 5, p 576 (2020)
Feline infectious peritonitis (FIP) is a viral disease with a high morbidity and mortality by the FIP virus (FIPV, virulent feline coronavirus). Several antiviral drugs for FIP have been identified, but many of these are expensive and not available i
Externí odkaz:
https://doaj.org/article/aaa8cc3c41d2448ca4c1fb063fc743be
Publikováno v:
Journal of Pharmacological Sciences, Vol 122, Iss 2, Pp 93-102 (2013)
AMP-activated protein kinase (AMPK) contributes to the acceleration of insulin signaling. However, the mechanism by which AMPK regulates insulin signaling remains unclear. Serine phosphorylation of insulin receptor substrate (IRS)-1 negatively regula
Externí odkaz:
https://doaj.org/article/9795fceec6c24583b90d51d219dd1ae2
Publikováno v:
Journal of Pharmacological Sciences, Vol 116, Iss 2, Pp 181-187 (2011)
Abstract.: Effects of azelnidipine were examined and compared with those of amlodipine on stunned myocardium in dogs. The left anterior descending (LAD) coronary artery was ligated for 20 min and subsequently released for 60 min. A vehicle, azelnidip
Externí odkaz:
https://doaj.org/article/7000d93408604162b38993f4f33adea2
Possible Mechanisms Underlying Statin-Induced Skeletal Muscle Toxicity in L6 Fibroblasts and in Rats
Publikováno v:
Journal of Pharmacological Sciences, Vol 109, Iss 1, Pp 94-101 (2009)
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors (statins) are safe and well-tolerated therapeutic drugs. However, they occasionally induce myotoxicity such as myopathy and rhabdomyolysis. Here, we investigated the mechanism of statin-induced myot
Externí odkaz:
https://doaj.org/article/e79b97ee26644adf8c117e5dc67461df
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 4, Pp 593-599 (2008)
Incomplete recovery of myocardial contraction after reperfusion following brief ischemia is called the “stunning phenomenon” in an animal experiment. A hydrophilic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor (statin) does
Externí odkaz:
https://doaj.org/article/a8646e886d044e688f37584bbe7f73f5
Publikováno v:
Journal of Pharmacological Sciences, Vol 107, Iss 1, Pp 80-89 (2008)
A number of patients with hyperlipidemia are prescribed 3-hydroxy-3-methylglutaryl-CoA reductase inhibitors that are concomitantly used along with the treatment of diabetes mellitus. The effects of atorvastatin and pravastatin on insulin-induced gluc
Externí odkaz:
https://doaj.org/article/07f332147d5f4e5fbf1188a047b136e0
Publikováno v:
Cell Biology International. 47:787-795
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a9f6c02fcf6308f8b708107b3d823cb
https://doi.org/10.1002/cbin.11982
https://doi.org/10.1002/cbin.11982
Publikováno v:
Pharmacology & Pharmacy. 14:59-71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c587af245a0dd0d1957ec4fa4d6c0504
https://doi.org/10.4236/pp.2023.143005
https://doi.org/10.4236/pp.2023.143005
Publikováno v:
Pharmacology & Pharmacy. 12:255-268
The molecular clock component Brain and Muscle Arnt-Like protein-1 (BMAL-1) affects various biologic processes, including cell survival, in numerous cell types. We previously demonstrated that BMAL1 positively regulates cell proliferation in Vascular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f443f6d54cf3fb0bf055e4016338779
https://doi.org/10.4236/pp.2021.1211022
https://doi.org/10.4236/pp.2021.1211022