Výsledky vyhledávání - "Kumarapillai Mohanan Nair Jagathnath Krishna"

Akademický článek

Impact of Additional Chromosomal Aberrations on the Disease Progression of Chronic Myelogenous Leukemia

Autor: Ramachandran Krishna Chandran, Narayanan Geetha, Kunnathur Murugesan Sakthivel, Raveendran Suresh Kumar, Kumarapillai Mohanan Nair Jagathnath Krishna, Hariharan Sreedharan

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

The emergence of additional chromosomal abnormalities (ACAs) in Philadelphia chromosome/BCR-ABL1 positive chronic myeloid leukemia (CML), is considered to be a feature of disease evolution. However, their frequency of incidence, impact on prognosis a

Externí odkaz: https://doaj.org/article/6d051bd32026448ca60a16ea3d437225

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Whole Exome Sequencing Identifies Cohesin Component STAG1 Mutation in de novo Acute Myeloid Leukemia (FAB M2): A Pilot Study with Cytogenetics, Clinical and Prognostic Implications

Autor: Narayanan Geetha, Kumarapillai Mohanan Nair Jagathnath Krishna, Kunnathur Murugesan Sakthivel, Hariharan Sreedharan, Thampirajan Vimaladevi Akhila Raj, Ramachandran Krishna Chandran

Publikováno v: Journal of Environmental Pathology, Toxicology and Oncology. 40:51-64

The clinical implications of cohesin gene complex mutation in acute myeloid leukemia (AML) are not well characterized. In the present study, a cohort of 152 de novo unselected adult AML patients underwent conventional and molecular cytogenetic analys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a8efb78e260e02285b0138943abb05
https://doi.org/10.1615/jenvironpatholtoxicoloncol.2020035890

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Differential gene expression changes and their implication on the disease progression in patients with Chronic Myeloid Leukemia

Autor: Narayanan Geetha, Ramachandran Krishna Chandran, Raveendran Suresh Kumar, Kumarapillai Mohanan Nair Jagathnath Krishna, Kunnathur Murugesan Sakthivel, Hariharan Sreedharan

Publikováno v: Blood Cells, Molecules, and Diseases. 77:51-60

The molecular mechanisms responsible for disease progression of CML are not conclusive. The main functional changes associated with disease evolution in CML was high proliferation rate, decreased apoptosis, blockade of differentiation, and strong res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb6192db84fddcbef740ac5dffbf852
https://doi.org/10.1016/j.bcmd.2019.03.004

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