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Covalent Cysteine Targeting of Bruton's Tyrosine Kinase (BTK) Family by Withaferin-A Reduces Survival of Glucocorticoid-Resistant Multiple Myeloma MM1 Cells.

Autor: Logie E; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Chirumamilla CS; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Perez-Novo C; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Shaw P; Plasma Lab for Applications in Sustainability and Medicine Antwerp (PLASMANT), Department of Chemistry, University of Antwerp, 2610 Wilrijk, Belgium., Declerck K; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Palagani A; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Rangarajan S; PamGene International B.V., 5211 Hertogenbosch, The Netherlands., Cuypers B; Biomedical Informatics Network Antwerp (Biomina), Department of Informatics, University of Antwerp, 2610 Wilrijk, Belgium., De Neuter N; Biomedical Informatics Network Antwerp (Biomina), Department of Informatics, University of Antwerp, 2610 Wilrijk, Belgium., Mobashar Hussain Urf Turabe F; Lymphocyte Signaling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 1308232, Singapore., Kumar Verma N; Lymphocyte Signaling Research Laboratory, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 1308232, Singapore., Bogaerts A; Plasma Lab for Applications in Sustainability and Medicine Antwerp (PLASMANT), Department of Chemistry, University of Antwerp, 2610 Wilrijk, Belgium., Laukens K; Biomedical Informatics Network Antwerp (Biomina), Department of Informatics, University of Antwerp, 2610 Wilrijk, Belgium., Offner F; Hematology, Department of Internal Medicine, Ghent University, 9000 Ghent, Belgium., Van Vlierberghe P; Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium., Van Ostade X; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium., Berghe WV; Laboratory of Protein Science, Proteomics and Epigenetic Signaling (PPES) and Integrated Personalized and Precision Oncology Network (IPPON), Department of Biomedical Sciences, Campus Drie Eiken, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.

Publikováno v: Cancers [Cancers (Basel)] 2021 Mar 31; Vol. 13 (7). Date of Electronic Publication: 2021 Mar 31.