Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kumar Kotlo"'
Autor:
Kumar Kotlo, Yongna Xing, Sonia Lather, Jean Michel Grillon, Keven Johnson, Randal A Skidgel, R John Solaro, Robert S Danziger
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85000 (2014)
Serine-threonine Protein phosphatase 2 A (PP2A), a member of the PPP family of phosphatases, regulates a variety of essential cellular processes, including cell-cycling, DNA replication, transcription, translation, and secondary signaling pathways. I
Externí odkaz:
https://doaj.org/article/6d237a7cceaa4b12bb99510f9ee5bce7
Publikováno v:
Advances in Drug and Alcohol Research. 3
Alcohol use disorder (AUD) has a complex, multifactorial etiology involving dysregulation across several brain regions and peripheral organs. Acute and chronic alcohol consumption cause epigenetic modifications in these systems, which underlie change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eb4e9805a86ce766015b1857ae59d1e
https://doi.org/10.3389/adar.2023.10871
https://doi.org/10.3389/adar.2023.10871
Publikováno v:
Pathobiology. 89:81-91
Introduction: The potential role of accumulation of chondroitin sulfates (CSs) in the pathobiology of COVID-19 has not been examined. Accumulation may occur by increased synthesis or by decline in activity of the enzyme arylsulfatase B (ARSB; N-acety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6013c8dfc4b6c69f30c8f60ffedcee
https://doi.org/10.1159/000519542
https://doi.org/10.1159/000519542
Publikováno v:
The FASEB Journal
The precise mechanisms by which Covid-19 infection leads to hypoxia and respiratory failure have not yet been elucidated. Interactions between sulfated glycosaminoglycans (GAGs) and the SARS-CoV-2 spike glycoprotein have been identified as participat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a34288636971343881aef65b4a75a4
http://europepmc.org/articles/PMC8239765
http://europepmc.org/articles/PMC8239765
The spike protein of SARS-CoV-2 binds to respiratory epithelium through the ACE2 receptor, an endogenous receptor for Angiotensin II (AngII). The mechanisms by which this viral infection leads to hypoxia and respiratory failure have not yet been eluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c113efdd3e700932abfab7848a9a96
https://doi.org/10.1101/2020.06.25.171975
https://doi.org/10.1101/2020.06.25.171975
Autor:
Brian T. Layden, Kristen Lednovich, Kai Xu, Kumar Kotlo, Pradeep K. Dudeja, Shubha Priyamvada, Medha Priyadarshini
Publikováno v:
Journal of the Endocrine Society
Olfactory receptor OLFR78 is a G protein-coupled receptor (GPCR) which is activated by short chain fatty acids (SCFAs), especially propionate. OLFR78 is expressed in islets as well as intestinal epithelial cells. Based on these properties, we hypothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d3f352c0706e36324a69b5934122a8
http://europepmc.org/articles/PMC6555068
http://europepmc.org/articles/PMC6555068
Autor:
Brian T. Layden, Pradeep K. Dudeja, Anoop Kumar, Arivarasu Natarajan Anbazhagan, Shubha Priyamvada, Dulari Jayawardena, Kumar Kotlo
Publikováno v:
Gastroenterology. 158:S-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f669253c164b5e7aa562a35dd9bd23
https://doi.org/10.1016/s0016-5085(20)31198-7
https://doi.org/10.1016/s0016-5085(20)31198-7
Publikováno v:
Comprehensive Physiology
Nutrient sensing is a mechanism for organisms to sense their environment. In larger animals, including humans, the intestinal tract is a major site of nutrient sensing for the body, not surprisingly, as this is the central location where nutrients ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce8852e35b3e8fbaa3b553f34b9aa82
https://europepmc.org/articles/PMC6058973/
https://europepmc.org/articles/PMC6058973/
Publikováno v:
Alcohol Clin Exp Res
BACKGROUND: Binge drinking is associated with increased risk for cardiovascular (CV) disease. MicroRNA-21 (miR21) is upregulated in the setting of excessive alcohol consumption and CV disease. Therefore, the goal of this study was to examine the vaso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5a3cf0d7a9587fbce8a0f293a7b6b0
https://europepmc.org/articles/PMC7286284/
https://europepmc.org/articles/PMC7286284/
Autor:
Sumit Bhattacharyya, Leo Feferman, Shah Tejaskumar, Robert J. Linhardt, Bo Yang, Joanne K. Tobacman, Kumar Kotlo, Robert S Danziger
Publikováno v:
Glycoconjugate Journal. 30:667-676
N -acetylgalactosamine-4-sulfatase (Arylsulfatase B; ARSB) is the enzyme that removes sulfate groups from the N-acetylgalactosamine-4-sulfate residue at the non-reducing end of chondroitin-4-sulfate (C4S) and dermatan sulfate (DS). Previous studies d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bbed67d9269e0a17464bbcb00ed07e
https://doi.org/10.1007/s10719-013-9468-8
https://doi.org/10.1007/s10719-013-9468-8