Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kumar Kopparapu P"'
Autor:
Anders Karlsson, Leonarda Achá Alarcón, Beatriz Piñeiro-Iglesias, Gunnar Jacobsson, Susann Skovbjerg, Edward R. B. Moore, Pradeep Kumar Kopparapu, Tao Jin, Roger Karlsson
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1725 (2024)
Staphylococcus aureus is a pathogen known to cause a wide range of infections. To find new targets for identification and to understand host–pathogen interactions, many studies have focused on surface proteins. We performed bacterial-cell surface-s
Externí odkaz:
https://doaj.org/article/95464fd02f7845868df1ece1f6f3585a
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7456 (2024)
Staphylococcal toxic shock syndrome (STSS) is a rare, yet potentially fatal disease caused by Staphylococcus aureus (S. aureus) enterotoxins, known as superantigens, which trigger an intense immune response. Our previous study demonstrated the protec
Externí odkaz:
https://doaj.org/article/8ee59809b4a84f94a38fa8c002b72d91
Autor:
Priti Gupta, Zhicheng Hu, Pradeep Kumar Kopparapu, Meghshree Deshmukh, Tibor Sághy, Majd Mohammad, Tao Jin, Cecilia Engdahl
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Aging alters immunoglobulin production, affecting the humoral immune response. Toll-like receptor 2 (TLR2) recognizes Staphylococcus aureus (S. aureus) which causes bacteremia with high mortality in the elderly. To understand how TLR2 and ag
Externí odkaz:
https://doaj.org/article/6fee2f1e9119491b931625959ae85a15
Autor:
Zhicheng Hu, Pradeep Kumar Kopparapu, Patrick Ebner, Majd Mohammad, Simon Lind, Anders Jarneborn, Claes Dahlgren, Michelle Schultz, Meghshree Deshmukh, Rille Pullerits, Mulugeta Nega, Minh-Thu Nguyen, Ying Fei, Huamei Forsman, Friedrich Götz, Tao Jin
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Phenol-soluble modulin α and β display divergent roles in staphylococcal infection and its associated septic arthritis - whereas PSMα is a virulence factor for neutrophils that worsens infection, PSMβ protects from the development of septic arthr
Externí odkaz:
https://doaj.org/article/798d297117de42cb9eb21e795269552e
Autor:
Meghshree Deshmukh, Santhilal Subhash, Zhicheng Hu, Majd Mohammad, Anders Jarneborn, Rille Pullerits, Tao Jin, Pradeep Kumar Kopparapu
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Septic arthritis is the most aggressive joint disease associated with high morbidity and mortality. The interplay of the host immune system with the invading pathogens impacts the pathophysiology of septic arthritis. Early antibiotic treatment is cru
Externí odkaz:
https://doaj.org/article/0e10270b40ac4d2bb524fb98d7ad51d5
Autor:
Majd Mohammad, Manli Na, Zhicheng Hu, Minh-Thu Nguyen, Pradeep Kumar Kopparapu, Anders Jarneborn, Anna Karlsson, Abukar Ali, Rille Pullerits, Friedrich Götz, Tao Jin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Mohammad et al. show that subcutaneous injection of Staphylococcus aureus lipoproteins (Lpp) leads to the infiltration of neutrophils and monocytes/macrophages, inducing skin lesions in mice. They find that S. aureus Lpp promotes abscess formation, w
Externí odkaz:
https://doaj.org/article/5f86a771da2a4034989658dbfdd8a8f5
Autor:
James D. Windsor, Tyler D. Robinson, Ravi kumar Kopparapu, Amber V. Young, David E. Trilling, Joe LLama
Publikováno v:
The Planetary Science Journal, Vol 4, Iss 5, p 94 (2023)
Clouds are ubiquitous: they arise for every solar system planet that possesses an atmosphere and have also been suggested as a leading mechanism for obscuring spectral features in exoplanet observations. As exoplanet observations continue to improve,
Externí odkaz:
https://doaj.org/article/f305da2feede46fd823d6c51a88eed03
Autor:
Sara Wernig-Zorc, Mukesh Pratap Yadav, Pradeep Kumar Kopparapu, Mats Bemark, Hallgerdur Lind Kristjansdottir, Per-Ola Andersson, Chandrasekhar Kanduri, Meena Kanduri
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-15 (2019)
Abstract Background Chronic lymphocytic leukemia (CLL) has been a good model system to understand the functional role of 5-methylcytosine (5-mC) in cancer progression. More recently, an oxidized form of 5-mC, 5-hydroxymethylcytosine (5-hmC) has gaine
Externí odkaz:
https://doaj.org/article/1a8692c51def43bfb205746d752b7681
Publikováno v:
AIMS Geosciences, Vol 4, Iss 4, Pp 180-191 (2018)
1D climate models are less sophisticated than 3D global circulation models (GCMs), however their computational time is much less expensive, allowing a large number of runs in a short period of time to explore a wide parameter space. Exploring paramet
Externí odkaz:
https://doaj.org/article/196cdd55350f4ffea3fa15783afdb037
Autor:
Pradeep Kumar Kopparapu, Meghshree Deshmukh, Zhicheng Hu, Majd Mohammad, Marco Maugeri, Friedrich Götz, Hadi Valadi, Tao Jin
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7099 (2021)
Staphylococcal aureus (S. aureus), a Gram-positive bacteria, is known to cause various infections. Extracellular vesicles (EVs) are a heterogeneous array of membranous structures secreted by cells from all three domains of life, i.e., eukaryotes, bac
Externí odkaz:
https://doaj.org/article/8f872b1d884e490c8305cb6b4096a568