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pro vyhledávání: '"Kumar Gadamsetti"'
Autor:
Mark Liu, Chenkou Wei, Dale Vanyo, Rachel Mathew, William J. Winter, F. Taha Comezoglu, Kumar Gadamsetti, Victor W. Rosso, Ciro J. Spagnuolo, Gerald L. Powers, Atul S. Kotnis, Raymond E. Weaver, Ambarish K. Singh, Bich D. Phan, David A. Lust, Merrill L. Davies, Kenneth S. Bembenek, Wen-Sen Li, Venkatapuram A. Palaniswamy
Publikováno v:
Organic Process Research & Development. 7:25-27
The final step of the semisynthetic route to paclitaxel involves cleavage of the triethylsilyl (TES) protecting group from the C-7 hydroxyl group. Paclitaxel is an extremely complex molecule, and standard deprotection conditions led to formation of s