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Vybrat výsledek číslo 1 1

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis

Autor: Ferrada MA, Savic S, Collins JC, Alessi H, Gutierrez-Rodrigues F, Kumar DBU, Wilson L, Goodspeed W, Topilow JS, Paik JJ, Poulter JA, Kermani TA, Koster MJ, Warrington KJ, Cargo C, Tattersall RS, Duncan CJA, Cantor A, Hoffmann P, Payne EM, Bonnekoh H, Krause K, Cowen EW, Calvo KR, Patel BA, Ombrello AK, Kastner DL, Young NS, Werner A, Grayson PC, Beck DB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07a317bdb05d4f8f1b32c954039fa049

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Vybrat výsledek číslo 2 2

Akademický článek

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis.

Autor: Ferrada MA; National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NHS), Bethesda, MD., Savic S; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, United Kingdom.; National Institute for Health and Care Research (NIHR)-Leeds Biomedical Research Centre, United Kingdom., Cardona DO; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, NY, NY., Collins JC; National Institute of Dental and Craniofacial Research and., Alessi H; National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NHS), Bethesda, MD., Gutierrez-Rodrigues F; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Kumar DBU; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, NY, NY., Wilson L; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Goodspeed W; National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NHS), Bethesda, MD., Topilow JS; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD., Paik JJ; Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD., Poulter JA; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, United Kingdom., Kermani TA; Division of Rheumatology, University of California Los Angeles, Los Angeles, CA., Koster MJ; Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN., Warrington KJ; Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN., Cargo C; Haematological Malignancy Diagnostic Service, Leeds Cancer Centre, St James's University Hospital, Leeds, United Kingdom., Tattersall RS; Sheffield Teaching Hospitals National Institutes of Health (NHS) Foundation, Sheffield, United Kingdom., Duncan CJA; Immunity and Inflammation Theme, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Cantor A; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, NY, NY., Hoffmann P; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Payne EM; Research Department of Hematology, Cancer Institute, University College London, London, United Kingdom.; National Institute for Health and Care Research (NIHR)/University College London Hospitals (UCLH) Clinical Research Facility, University College London Hospitals National Institutes of Health (NHS) Foundation Trust, London, United Kingdom., Bonnekoh H; Institute of Allergology, Charite - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Allergology and Immunology, Berlin, Germany.; Autoinflammation Reference Center Charite (ARC2), Charite - Universitätsmedizin Berlin, Germany., Krause K; Institute of Allergology, Charite - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Allergology and Immunology, Berlin, Germany.; Autoinflammation Reference Center Charite (ARC2), Charite - Universitätsmedizin Berlin, Germany., Cowen EW; National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NHS), Bethesda, MD., Calvo KR; Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD; and., Patel BA; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Ombrello AK; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Kastner DL; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD., Young NS; National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD., Werner A; National Institute of Dental and Craniofacial Research and., Grayson PC; National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NHS), Bethesda, MD., Beck DB; National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.; Center for Human Genetics and Genomics, New York University Grossman School of Medicine, NY, NY.; Division of Rheumatology, Department of Medicine, New York University Grossman School of Medicine, NY, NY.

Publikováno v: Blood [Blood] 2022 Sep 29; Vol. 140 (13), pp. 1496-1506.

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Vybrat výsledek číslo 3 3

Akademický článek

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.

Autor: Baulies A; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Montero J; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Matías N; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Insausti N; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Terrones O; Unidad de Biofísica (Centro Mixto Consejo Superior de Investigaciones Científicas-Universidad del País Vasco/Euskal Herriko Unibertsitatea), Universidad del País Vasco/Euskal Herriko Unibertsitatea, 48080 Bilbao, Spain., Basañez G; Unidad de Biofísica (Centro Mixto Consejo Superior de Investigaciones Científicas-Universidad del País Vasco/Euskal Herriko Unibertsitatea), Universidad del País Vasco/Euskal Herriko Unibertsitatea, 48080 Bilbao, Spain., Vallejo C; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Conde de La Rosa L; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Martinez L; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Robles D; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain., Morales A; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain., Abian J; CSIC/UAB Proteomics Laboratory, IIBB-CSIC, 08036 Barcelona, Spain., Carrascal M; CSIC/UAB Proteomics Laboratory, IIBB-CSIC, 08036 Barcelona, Spain., Machida K; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, USA., Kumar DBU; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, USA., Tsukamoto H; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, USA; Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA., Kaplowitz N; University of Southern California Research Center for Liver Diseases, Keck School of Medicine, USC, Los Angeles, CA, USA., Garcia-Ruiz C; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, USA; University of Southern California Research Center for Liver Diseases, Keck School of Medicine, USC, Los Angeles, CA, USA. Electronic address: cgrbam@iibb.csic.es., Fernández-Checa JC; Department of Cell Death and Proliferation, Instituto de Investigaciones Biomédicas de Barcelona, Consejo Superior de Investigaciones Científicas, 08036 Barcelona, Spain; Liver Unit and Hospital Clínic i Provincial, IDIBAPS, and Centro de Investigación Biomédica en Red (CIBERehd), Spain; Southern California Research Center for ALPD and Cirrhosis, Los Angeles, CA, USA; University of Southern California Research Center for Liver Diseases, Keck School of Medicine, USC, Los Angeles, CA, USA. Electronic address: checa229@yahoo.com.

Publikováno v: Redox biology [Redox Biol] 2018 Apr; Vol. 14, pp. 164-177. Date of Electronic Publication: 2017 Sep 14.

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Vybrat výsledek číslo 4 4

Akademický článek

Lysine-specific methyltransferase Set7/9 in stemness, differentiation, and development.

Autor: Daks, Alexandra¹ (AUTHOR) alexandra.daks@gmail.com, Parfenyev, Sergey¹ (AUTHOR), Shuvalov, Oleg¹ (AUTHOR), Fedorova, Olga¹ (AUTHOR), Nazarov, Alexander¹ (AUTHOR), Melino, Gerry² (AUTHOR), Barlev, Nickolai A.^1,3 (AUTHOR) nikolai.barlev@nu.edu.kz

Publikováno v: Biology Direct. 5/29/2024, Vol. 19 Issue 1, p1-16. 16p.

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Vybrat výsledek číslo 5 5

Akademický článek

The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan.

Autor: Kotzin JJ; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Spencer SP; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., McCright SJ; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Kumar DBU; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA.; Department of Genetics and Genomic Sciences, University of Connecticut Health Center, Farmington, Connecticut, 06032, USA., Collet MA; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA., Mowel WK; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Elliott EN; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA., Uyar A; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA., Makiya MA; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892., Dunagin MC; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104., Harman CCD; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Howard Hughes Medical Institute, Yale University, New Haven, CT 06510, USA., Virtue AT; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Zhu S; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA., Bailis W; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA., Stein J; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Howard Hughes Medical Institute, Yale University, New Haven, CT 06510, USA., Hughes C; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Howard Hughes Medical Institute, Yale University, New Haven, CT 06510, USA., Raj A; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104., Wherry EJ; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Goff LA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore, Maryland 21205, USA.; Department of Neuroscience, Johns Hopkins University, Baltimore, Maryland 21205, USA., Klion AD; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892., Rinn JL; Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA., Williams A; The Jackson Laboratory for Genomic Medicine, Farmington, Connecticut, 06032, USA.; Department of Genetics and Genomic Sciences, University of Connecticut Health Center, Farmington, Connecticut, 06032, USA., Flavell RA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.; Howard Hughes Medical Institute, Yale University, New Haven, CT 06510, USA., Henao-Mejia J; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Division of Transplant Immunology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104.

Publikováno v: Nature [Nature] 2016 Sep 08; Vol. 537 (7619), pp. 239-243. Date of Electronic Publication: 2016 Aug 15.

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Vybrat výsledek číslo 6 6

Akademický článek

A state-of-the-art review on the NRF2 in Hepatitis virus-associated liver cancer.