Zobrazeno 1 - 10
of 41 062
pro vyhledávání: '"Kumar D"'
Autor:
Wagner IV, Boopathiraj N, Lentz C, Dorairaj EA, Draper C, Kumar D, Checo L, Miller DD, Krambeer C, Dorairaj S
Publikováno v:
Clinical Ophthalmology, Vol Volume 18, Pp 713-721 (2024)
Isabella V Wagner,1 Nithya Boopathiraj,1 Connor Lentz,1 Emily Aashna Dorairaj,2 Christian Draper,3 Devesh Kumar,4 Leticia Checo,1 Darby D Miller,1 Chelsey Krambeer,1 Syril Dorairaj1 1Department of Ophthalmology, Mayo Clinic, Jacksonville, FL, USA; 2D
Externí odkaz:
https://doaj.org/article/8ff1fdb987fb4bc19e6d15365419758c
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 16, Iss 6, Pp 1798-1800 (2024)
BackgroundOrthodontic treatment planning involves the precise assessment of dental and skeletal anomalies, which can be facilitated by AI-enhanced diagnostic tools. Materials and MethodsA total of 100 orthodontic cases were included in this RCT. Pati
Externí odkaz:
https://doaj.org/article/6ef65a6a038e4d00996fc693f5827dd1
Autor:
Daniel S. Lenchner, Zaritza O. Petrova, Lisa Hunihan, Kumar D. Ashtekar, Zenta Walther, Frederick H. Wilson
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract EGFR tyrosine kinase inhibitors (TKIs) have transformed the treatment of EGFR-mutated non-small cell lung carcinoma (NSCLC); however, therapeutic resistance remains a clinical challenge. Acquired secondary EGFR mutations that increase ATP af
Externí odkaz:
https://doaj.org/article/df24accd246b45819fd7a53ffc9348ab
Autor:
Krishna C. Mudumbi, Eric A. Burns, David J. Schodt, Zaritza O. Petrova, Anatoly Kiyatkin, Lucy W. Kim, Emma M. Mangiacapre, Irais Ortiz-Caraveo, Hector Rivera Ortiz, Chun Hu, Kumar D. Ashtekar, Keith A. Lidke, Diane S. Lidke, Mark A. Lemmon
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113603- (2024)
Summary: The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase with important roles in many cellular processes as well as in cancer and other diseases. EGF binding promotes EGFR dimerization and autophosphorylation through interac
Externí odkaz:
https://doaj.org/article/3090522f0d974b3a9a1c31bec81b0de1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Histone deacetylase 3 (HDAC3) and nuclear receptor co-repressor (NCoR1/2) are epigenetic regulators that play a key role in gene expression and metabolism. HDAC3 is a class I histone deacetylase that functions as a transcriptional co-repressor, modul
Externí odkaz:
https://doaj.org/article/326bb1f37528494c8700580aed27bfaf
Autor:
Iris K. van Alderwerelt van Rosenburgh, David M. Lu, Michael J. Grant, Steven E. Stayrook, Manali Phadke, Zenta Walther, Sarah B. Goldberg, Katerina Politi, Mark A. Lemmon, Kumar D. Ashtekar, Yuko Tsutsui
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Although small molecule tyrosine kinase inhibitors are effective in lung cancer driven by mutated EGFR, some receptor variants fail to respond. Here, the authors identify structural features of an important set of EGFR variants with reduced inhibitor
Externí odkaz:
https://doaj.org/article/b04886b84f654ae4b677dfc2b5e44cc2
Autor:
Pande G, Hatti M, Rai MK, Rai P, Kumar K, VP K, Nehra A, Kumar S, Ranjan Rout S, Mishra SK, Kumar D, Kumar U, Mishra P, Majeed A, Saraswat VA, Singh K, Singh H, Misra DP, Agarwal V
Publikováno v:
Journal of Inflammation Research, Vol Volume 15, Pp 5027-5039 (2022)
Gaurav Pande,1 Manjunath Hatti,1 Mohit Kumar Rai,2 Praveer Rai,1 Kamlesh Kumar,1 Krishna VP,1 Abhimanyu Nehra,1 Sudeep Kumar,3 Smarak Ranjan Rout,3 Sourav Kumar Mishra,3 Dinesh Kumar,4 Umesh Kumar,4 Prabhaker Mishra,5 Abdul Majeed,1 Vivek Anand Saras
Externí odkaz:
https://doaj.org/article/3eb6d49a1d2e43c78e2b32f3bff13f25
Autor:
Balaji K. Srinivas, Aya Bourdi, Jacob D. O'Regan, Kumar D. Malavalli, Nour‐Eddine Rhaleb, Souad Belmadani, Khalid Matrougui
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 14 (2023)
Background Heart failure with preserved ejection fraction (HFpEF) is a significant unmet need in cardiovascular medicine and remains an untreatable cardiovascular disease. The role and mechanism of interleukin‐1β in HFpEF pathogenesis are poorly u
Externí odkaz:
https://doaj.org/article/8596badf93e948aca778f95610bd30c8
Publikováno v:
E3S Web of Conferences, Vol 511, p 01009 (2024)
This research examines the production, characteristics, and possible uses of biodegradable polymer nanocomposites in the field of sustainable agriculture. By doing a thorough examination of the experimental data, significant discoveries have been cla
Externí odkaz:
https://doaj.org/article/89e1cbc09773433394a03627d7cd38e4
Autor:
Bloomfield H.C., Hillier J., Griffin A., Kay A.L., Shaffrey L.C., Pianosi F., James R., Kumar D., Champion A., Bates P.D.
Publikováno v:
Weather and Climate Extremes, Vol 39, Iss , Pp 100550- (2023)
The risk posed by heavy rain and strong wind is now suspected to be exacerbated by the way they co-occur, yet this remains insufficiently understood to effectively plan and mitigate. This study systematically investigates the correlations between win
Externí odkaz:
https://doaj.org/article/8521fdad97df4db282cf4ddfd89d30d6