Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kumar, Samrat"'
Autor:
Subodh Kumar Samrat, Prashant Kumar, Yuchen Liu, Ke Chen, Hyun Lee, Zhong Li, Yin Chen, Hongmin Li
Publikováno v:
Viruses, Vol 16, Iss 8, p 1239 (2024)
Emergence of newer variants of SARS-CoV-2 underscores the need for effective antivirals to complement the vaccination program in managing COVID-19. The multi-functional papain-like protease (PLpro) of SARS-CoV-2 is an essential viral protein that not
Externí odkaz:
https://doaj.org/article/40faa96d7d12467c8e5d71124330b2a5
Autor:
Subodh Kumar Samrat, Qamar Bashir, Ran Zhang, Yiding Huang, Yuchen Liu, Xiangmeng Wu, Tyler Brown, Wei Wang, Y. George Zheng, Qing-Yu Zhang, Yin Chen, Zhong Li, Hongmin Li
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTSARS-CoV-2 has caused a global pandemic with significant humanity and economic loss since 2020. Currently, only limited options are available to treat SARS-CoV-2 infections for vulnerable populations. In this study, we report a universal fluo
Externí odkaz:
https://doaj.org/article/60c51fd2806c487b8bf9c42761d4bf04
Autor:
Weifeng Liang, Ming Gu, Lingxiang Zhu, Ziqi Yan, Dominik Schenten, Shelby Herrick, Hongmin Li, Subodh Kumar Samrat, Jiapeng Zhu, Yin Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/958b4414a85d4264a02d28dae220ac70
Autor:
Zhong Li, Jimin Xu, Yuekun Lang, Xiangmeng Wu, Saiyang Hu, Subodh Kumar Samrat, Anil M. Tharappel, Lili Kuo, David Butler, Yongcheng Song, Qing-Yu Zhang, Jia Zhou, Hongmin Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 4, Pp 1662-1670 (2022)
Zika virus (ZIKV) causes significant human diseases without specific therapy. Previously we found erythrosin B, an FDA-approved food additive, inhibited viral NS2B−NS3 interactions, leading to inhibition of ZIKV infection in cell culture. In this s
Externí odkaz:
https://doaj.org/article/825f512a044d416aad86d0b0d67c9f7d
Autor:
Xiangmeng Wu, Saiyang Hu, Hongmin Li, Yongcheng Song, Zhong Li, Lili Kuo, Anil Mathew Tharappel, Yuekun Lang, Jimin Xu, Qing Yu Zhang, Jia Zhou, David Butler, Subodh Kumar Samrat
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1662-1670
Zika virus (ZIKV) causes significant human diseases without specific therapy. Previously we found erythrosin B, an FDA-approved food additive, inhibited viral NS2B−NS3 interactions, leading to inhibition of ZIKV infection in cell culture. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5d1d0c29a11d9cefbb99394bef7948c
https://doi.org/10.1016/j.apsb.2021.10.017
https://doi.org/10.1016/j.apsb.2021.10.017
Publikováno v:
ACS Infectious Diseases
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide since its first incidence in Wuhan, China, in December 2019. Although the case fatality rate of COVID-19 appears to be l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb0c6f8630ad7fa527090a91722bb5c0
https://doi.org/10.1021/acsinfecdis.0c00456
https://doi.org/10.1021/acsinfecdis.0c00456
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146404 (2016)
Adenoviruses (Ad) are commonly used as vectors for gene therapy and/or vaccine delivery. Recombinant Ad vectors are being tested as vaccines for many pathogens. We have made a surprising observation that peptides derived from various hepatitis C viru
Externí odkaz:
https://doaj.org/article/933b91b003f644bb939122aac96b6c43
Autor:
Hongmin Li, Cheri A. Koetzner, Zhong Li, Menghang Xia, Anil Mathew Tharappel, Laura D. Kramer, Nicole Trudeau, Lili Kuo, Lianna D'Brant, Saiyang Hu, Subodh Kumar Samrat, David Butler, Yuekun Lang, Natasha Rugenstein, Jing Zhang, Srilatha Sakamuru, Ruili Huang
Publikováno v:
Emerging Microbes & Infections. 9:2404-2416
Many flaviviruses including the Dengue virus (DENV), Zika virus (ZIKV), West Nile virus, Yellow Fever virus, and Japanese encephalitis virus are significant human pathogens, unfortunately without any specific therapy. Here, we demonstrate that methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d7a1f8c75a98cad20c134590633255d
https://doi.org/10.1080/22221751.2020.1838954
https://doi.org/10.1080/22221751.2020.1838954
Autor:
Subodh Kumar Samrat, Jimin Xu, Xuping Xie, Eleonora Gianti, Haiying Chen, Jing Zou, Jason G. Pattis, Khaled Elokely, Hyun Lee, Zhong Li, Michael L. Klein, Pei-Yong Shi, Jia Zhou, Hongmin Li
Publikováno v:
Antiviral Research. 205:105381
SARS-CoV-2 has raised the alarm to search for effective therapy for this virus. To date several vaccines have been approved but few available drugs reported recently still need approval from FDA. Remdesivir was approved for emergency use only. In thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4840327d0c8de8a5d2a3e0878c9916
https://doi.org/10.1016/j.antiviral.2022.105381
https://doi.org/10.1016/j.antiviral.2022.105381
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86567 (2014)
Hepatitis C virus (HCV) leads to chronic infection in the majority of infected individuals due to lack, failure, or inefficiency of generated adaptive immune responses. In a minority of patients, acute infection is followed by viral clearance. The im
Externí odkaz:
https://doaj.org/article/09572644625c4a1f8c09912f2dabfcbd