Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kumar, Pichumani"'
Autor:
Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, William F. Flynn, Ruli Gao, David S. Baskin, Kumar Pichumani, Omkar B. Ijare, Stephanie L. Wood, Suzanne Z. Powell, David L. Haviland, Brittany C. Parker Kerrigan, Frederick F. Lang, Sujit S. Prabhu, Kristin M. Huntoon, Wen Jiang, Betty Y. S. Kim, Joshy George, Kyuson Yun
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Glioblastoma (GBM) is an immune cold tumour that is refractory to immunotherapy. Here, the authors identify molecular phenotypes of immune-suppressive and -promoting myeloid cells in GBM through single cell RNA sequencing and propose S100A4 as a regu
Externí odkaz:
https://doaj.org/article/8729e15cfe464e098e0bc6e28aafb086
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Electromagnetic fields (EMF) raise intracellular levels of reactive oxygen species (ROS) that can be toxic to cancer cells. Because weak magnetic fields influence spin state pairing in redox-active radical electron pairs, we hypothesize that they dis
Externí odkaz:
https://doaj.org/article/94fb975157344b4393de38b79e10c8c6
Autor:
Wolfgang Bogner, Omkar B. Ijare, Martyn A. Sharpe, David S. Baskin, Santosh A. Helekar, Sophie Lopez, Fabio Henrique Brasil da Costa, Gilbert Hangel, Robert Bachoo, Shashank Hambarde, Kumar Pichumani, Georg Widhalm
Publikováno v:
Neuro Oncol
Background We postulate that meningiomas undergo distinct metabolic reprogramming in tumorigenesis and unraveling their metabolic phenotypes provide new therapeutic insights. Glutamine catabolism is key to the growth and proliferation of tumors. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff95e62a4c8077b8f8ad60febf17037
https://doi.org/10.1093/neuonc/noab219
https://doi.org/10.1093/neuonc/noab219
Autor:
Omkar B. Ijare, Santosh A. Helekar, Martyn A. Sharpe, David S. Baskin, Kumar Pichumani, Shashank Hambarde
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:3577-3589
The mechanisms underlying anticancer effects of electromagnetic fields are poorly understood. An alternating electric field-generating therapeutic device called Optune™ device has been approved for the treatment of glioblastoma (GBM). We have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714671e6e7db69658214a023c62ac517
https://doi.org/10.1007/s00432-021-03787-0
https://doi.org/10.1007/s00432-021-03787-0
Autor:
Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, David Baskin, William Flynn, Ruli Gao, Kumar Pichumani, Omkar Ijare, Stephanie Wood, Suzanne Powell, David Haviland, Brittany Parker Kerrigan, Frederick Lang, Sujit Prabhu, Kristin Huntoon, Wen Jiang, Betty Kim, Joshy George, Kyuson Yun
Publikováno v:
Cancer Research. 83:5871-5871
With abundant pro-tumorigenic myeloid cells and few tumoricidal tumor-infiltrating lymphocytes ( Citation Format: Nourhan Abdelfattah, Parveen Kumar, Caiyi Wang, Jia-Shiun Leu, David Baskin, William Flynn, Ruli Gao, Kumar Pichumani, Omkar Ijare, Step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67dcf3b3de222d8119c58112fabac5a6
https://doi.org/10.1158/1538-7445.am2023-5871
https://doi.org/10.1158/1538-7445.am2023-5871
Autor:
Jonathan Hebert, Cole Holan, Kumar Pichumani, David S. Baskin, Martyn A. Sharpe, Omkar B. Ijare
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
The diagnosis of various histological subtypes of pituitary tumors is made using serum based hormone panel test. However, certain subtypes secrete more than one hormone, making the diagnosis ambiguous. Here, we performed 1H-NMR based metabolomic anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce40379df4c607d4a600c82aceb4a383
http://link.springer.com/article/10.1038/s41598-020-58244-8
http://link.springer.com/article/10.1038/s41598-020-58244-8
Publikováno v:
Neuro-Oncology. 24:vii268-vii268
Metabolic profiles of diffuse astrocytoma and recurrent tumor tissues were compared in a patient with diffuse astrocytoma who showed tumor recurrence and progressed to glioblastoma (GBM). The patient presented with a diffuse infiltrating tumor and wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f71cbb4c92fbd967f4fe00e04c7052a
https://doi.org/10.1093/neuonc/noac209.1036
https://doi.org/10.1093/neuonc/noac209.1036
Publikováno v:
Neuro-Oncology. 24:vii262-vii262
Oxaloacetate (OAA) inhibits the Warburg effect by reducing the glucose-derived lactate levels in human cancer cell lines. In dose ranging IC50 experiments with human hepatocellular carcinoma (HCC) cell lines, OAA inhibited cell growth in the concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25408c82fa3750574b15c07b04de6952
https://doi.org/10.1093/neuonc/noac209.1011
https://doi.org/10.1093/neuonc/noac209.1011
Autor:
Santosh A, Helekar, Shashank, Hambarde, Omkar B, Ijare, Kumar, Pichumani, David S, Baskin, Martyn A, Sharpe
Publikováno v:
Journal of cancer research and clinical oncology. 147(12)
The mechanisms underlying anticancer effects of electromagnetic fields are poorly understood. An alternating electric field-generating therapeutic device called Optune™ device has been approved for the treatment of glioblastoma (GBM). We have devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f81a794db459c308012657768b18b116
https://pubmed.ncbi.nlm.nih.gov/34477946
https://pubmed.ncbi.nlm.nih.gov/34477946
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Pituitary adenomas (PAs) are benign growths arising from epithelial cells in the adenohypophysis of the pituitary gland. To date, there has been no detailed metabolic characterization of PAs of various subtypes. In this study, we report nuclear magne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b150d3cd4e5f9d9a735603e15ffc9b75
http://link.springer.com/article/10.1038/s41598-019-38542-6
http://link.springer.com/article/10.1038/s41598-019-38542-6