Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kulrawee Sidthipong"'
Publikováno v:
Experimental and Therapeutic Medicine
Plasmacytoma is one of the most difficult types of leukemia to treat, and it often invades the bone down to the marrow resulting in the development of multiple myeloma. NF-κB is often constitutively activated, and promotes metastasis and drug resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23e0390cedc7a45688472bc8f892959
https://pubmed.ncbi.nlm.nih.gov/34504546
https://pubmed.ncbi.nlm.nih.gov/34504546
Autor:
Liyan Wang, Yinzhi Lin, Menjie Li, Kulrawee Sidthipong, Kazuo Umezawa, Nobuaki Kushida, Naomi Sumida, Jianqiang Tang
Publikováno v:
The Journal of Antibiotics. 70:987-990
In the course of our search for inhibitors of LPS-induced NO production from microbial strains, an ethyl acetate extract of Actinomycete SF2911, isolated from a soil sample collected in Okinawa Prefecture, Japan, showed the inhibitory activity. The a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e93d940f80f0df2d52d8930d9cfe459
https://doi.org/10.1038/ja.2017.83
https://doi.org/10.1038/ja.2017.83
Autor:
Kazuo Umezawa, Susumu Kobayashi, K. Kato, Naoki Koide, Takashi Yokochi, Wei Lin Yu, Satoshi Kishino, Kulrawee Sidthipong, Jun Ma, Shoshiro Okada, Yan Feng Wang
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(3)
(-)-Dehydroxymethylepoxyquinomicin ((-)-DHMEQ, 1) is a specific inhibitor of NF-κB. It binds to SH group in the specific cysteine residue of NF-κB components with its epoxide moiety to inhibit DNA binding. In the present research, we have designed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553915b01abecaa0015a6d6da317e6aa
https://pubmed.ncbi.nlm.nih.gov/28003138
https://pubmed.ncbi.nlm.nih.gov/28003138
Publikováno v:
Internal and emergency medicine. 8
Microorganisms and plants produce bioactive metabolites that are potentially useful in the treatment of disease. We have designed and synthesized DHMEQ as a specific inhibitor of NF-κB based on the structure of epoxyquinomicin. It directly binds to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4473d31c9522e025b579d5be15cb90c2
https://pubmed.ncbi.nlm.nih.gov/23504230
https://pubmed.ncbi.nlm.nih.gov/23504230
Autor:
Kazuo Umezawa, Liyan Wang, Yinzhi Lin, Kulrawee Sidthipong, Jianqiang Tang, Mengjie Li, Takashi Koyano, Thaworn Kowithayakorn, Kengo Sumiyoshi
Publikováno v:
HETEROCYCLES. 92:353
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc4b885e824f74710dfca39460ab6613
https://doi.org/10.3987/com-15-13386
https://doi.org/10.3987/com-15-13386