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Sampling time-dependent artifacts in single-cell genomics studies

Autor: Massoni-Badosa, R., Iacono, G., Moutinho, Catia, Kulis, M., Palau, N., Marchese, Domenica, Rodríguez-Ubreva, Javier, Ballestar, Esteban, Rodriguez-Esteban, G., Marsal, S., Aymerich, Marta, Colomer, Dolors, Campo, Elias, Julià Cano, Antonio, Martín-Subero, Jose Ignacio, Heyn, Holger, Universitat Autònoma de Barcelona

Publikováno v: Genome Biology, Vol 21, Iss 1, Pp 1-16 (2020)
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
GENOME BIOLOGY
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Genome Biology

Robust protocols and automation now enable large-scale single-cell RNA and ATAC sequencing experiments and their application on biobank and clinical cohorts. However, technical biases introduced during sample acquisition can hinder solid, reproducibl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e69c1cfd8e3400ebd57044176915d545
http://link.springer.com/article/10.1186/s13059-020-02032-0

PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia

Autor: Li, J, Hlavka-Zhang, J, Shrimp, JH, Piper, C, Dupéré-Richér, D, Roth, JS, Jing, D, Casellas Román, HL, Troche, C, Swaroop, A, Kulis, M, Oyer, JA, Will, CM, Shen, M, Riva, A, Bennett, RL, Ferrando, AA, Hall, MD, Lock, RB, Licht, JD

Mutations in epigenetic regulators are common in relapsed pediatric acute lymphoblastic leukemia (ALL). Here, we uncovered the mechanism underlying the relapse of ALL driven by an activating mutation of the NSD2 histone methyltransferase (p.E1099K).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::6117e72f189d2646dc936b4d9c32440f
https://hdl.handle.net/10453/169179

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Impact of Activating Killer Immunoglobulin-like Receptor Genotype on Outcome of Unrelated Donor–Hematopoietic Cell Transplantation

Autor: Giebel, S., Nowak, I., Wojnar, J., Markiewicz, M., Dziaczkowska, J., Wylezol, I., Krawczyk-Kulis, M., Bloch, R., Kusnierczyk, P., Holowiecki, J.

Publikováno v: In Transplantation Proceedings 2006 38(1):287-291