Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kuldip Thusu"'
Autor:
Louis M. Fink, Kuldip Thusu, Angie Stone, B S Baliga, Medha Munshi, V A Fonseca, Ahmad Aljada, Paresh Dandona
Publikováno v:
Southern Medical Journal. 90:903-906
Background Non-insulin-dependent diabetes mellitus (NIDDM) and hyperhomocysteinemia are both associated with increased lipid peroxidation (oxidative stress). This may contribute to the accelerated vascular disease associated with these conditions. It
Autor:
Priya Mohanty, Elizabeth Szudzik, Kuldip Thusu, Muhammad Arian, Paresh Dandona, Rashmi Tomar, Ajay Chaudhuri, Arindam Bandyopadhyay
Publikováno v:
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists. 4(5)
To assess whether, in the treatment of non-insulin-dependent diabetes mellitus (NIDDM), (1) metformin in conjunction with insulin can safely cause a decrease in glycosylated hemoglobin (HbA1c) to 7% or less and (2) this combination therapy may result
Publikováno v:
Critical care medicine. 27(11)
To determine whether hydrocortisone given intravenously inhibits reactive oxygen species (ROS) generation by polymorphonuclear neutrophils (PMNLs) in vivo and, if so, to describe the pharmacodynamics of this effect.A prospective, open label study in
Autor:
Madonna Tomani, Anu Prabhala, Paresh Dandona, Frank González, Kuldip Thusu, Ehad Abdel-Rahman
Publikováno v:
Metabolism: clinical and experimental. 48(4)
Since an increase in tumor necrosis factor alpha (TNFalpha) expression has been associated with insulin resistance, this study was undertaken to determine the status of circulating TNFalpha and the relationship of TNFalpha with insulin levels, body w
Autor:
Kuldip Thusu, Paresh Dandona, Ehad Abdel-Rahman, Ruth S. Weinstock, Thomas A. Wadden, Ahmad Aljada
Publikováno v:
The Journal of clinical endocrinology and metabolism. 83(8)
In view of the recent demonstration that obesity in animals and humans is associated with an increase in tumor necrosis factor-α (TNFα) expression, that this expression falls with weight loss, and that TNFα may specifically inhibit insulin action,
Publikováno v:
Metabolism: clinical and experimental. 47(7)
Corticosteroids are known to exert antiinflammatory and immunosuppressive effects. Since reactive oxygen species (ROS) induce tissue damage and inflammation and since mononuclear cells (MNCs) generate ROS, we investigated whether corticosteroids inhi
Autor:
Bruce A. Davidson, Parish Dandona, Kent J. Johnson, N. Nader-Djalal, Paul R. Knight, Bruce A. Holm, Kuldip Thusu
Publikováno v:
Anesthesia and analgesia. 87(1)
Hyperoxia increases pulmonary damage after acid aspiration. We hypothesize that free radicals play a role in acute lung injury. To examine this hypothesis, we injured rats by intratracheal instillation of acidic isotonic sodium chloride solution (NS)
Autor:
Paresh Dandona, Hratch L. Karamanoukian, Michael G. Caty, Kuldip Thusu, Jon E. Rossman, Richard G. Azizkhan, Shan Zheng
Publikováno v:
The Journal of surgical research. 73(1)
The authors investigated whether amelioration of intestinal mucosal injury, due to ischemia-reperfusion (I/R), with oxygenated perfluorocarbon (PFC) would reduce an oxidant-generated lung injury. The small intestine is increasingly recognized as a pr
Autor:
Paresh Dandona, Thomas M. Nicotera, Kuldip Thusu, J Makowski, B.D. Snyder, D Armstrong, Stephen Cook
Publikováno v:
Lancet (London, England). 347(8999)
Increased production of reactive oxygen species (ROS) and lipid peroxidation may contribute to vascular complications in diabetes. to test whether DNA is also oxidatively damaged in diabetes, we measured 8-hydroxydeoxyguanosine (8-OHdG), an indicator