Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kuldip K. Mirakhur"'
Autor:
Paige A. Ebert, Kuldip K Mirakhur, Amanda S Wilsey, Debra A. Weisbecker, James S Polakowski, Sabine Sadilek, Scott W Mittelstadt, Yevgeniya E Koshman, Brandan M Bird, C Michael Foley, Chris L Medina
Publikováno v:
Comp Med
Successful implementation of automated blood sampling (ABS) into a telemetry instrumented canine cardiovascular model provides simultaneous cardiovascular assessment of novel compounds while collecting multiple blood samples for analysis of drug leve
Autor:
Yevgeniya E. Koshman, Amanda S. Wilsey, Brandan M. Bird, Sabine Sadilek, Debra A. Weisbecker, Paige A. Ebert, Kuldip K. Mirakhur, James S. Polakowski, Gary A. Gintant, C. Michael Foley, Scott W. Mittelstadt
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 111:107003
Publikováno v:
Zentralblatt für Veterinärmedizin Reihe A. 27:730-739
Summary Seven clinically healthy buffalo calves (62–194 kg.) were anaesthetized with 5% thiopental sodium (1 g./100 kg.) to evaluate the effects of this agent in this species. There was significant tachycardia without any appreciable abnormality in
Publikováno v:
Veterinary Anaesthesia and Analgesia. 36:110-123
Objective To evaluate and compare the cardiopulmonary effects of induction of anesthesia with isoflurane (Iso), ketamine–diazepam (KD), or propofol–diazepam (PD) in hypovolemic dogs. Study design Prospective randomized cross–over trial. Animals
Publikováno v:
Vaccine. 25:8469-8479
We previously demonstrated that oral DNA vaccination of the third trimester fetus may be an effective strategy to prevent vertical disease transmission despite an immature immune system and the possibility of developing tolerance. The present investi
Publikováno v:
American Journal of Veterinary Research. 68:1287-1293
Objective—To compare the cardiopulmonary effects of administration of a solution of xylazine, guaifenesin, and ketamine (XGK) or inhaled isoflurane in mechanically ventilated calves undergoing surgery. Animals—13 male calves 2 to 26 days of age.
Autor:
Anju Manuja, Philip J. Griebel, Radhey S. Kaushik, M. Arshud Dar, Lorne A. Babiuk, George Mutwiri, Hugh G.G. Townsend, Arthur M. Krieg, A. K. Nichani, Kuldip K. Mirakhur
Publikováno v:
Veterinary Immunology and Immunopathology. 115:357-368
Mucosal delivery of CpG oligodeoxynucleotide (ODN) in mice has been shown to induce potent innate immunostimulatory responses and protection against infection. We evaluated the efficacy of CpG ODN in stimulating systemic innate immune responses in sh
Autor:
Francisco José Teixeira Neto, Carolyn L. Kerr, Sumit Durongphongtorn, Kuldip K Mirakhur, Wayne N. McDonell
Publikováno v:
American Journal of Veterinary Research. 67:32-42
Objective—To compare hemodynamic, clinicopathologic, and gastrointestinal motility effects and recovery characteristics of halothane and isoflurane in horses undergoing arthroscopic surgery. Animals—8 healthy adult horses. Procedure—Anesthesia
Autor:
Bryan Coburn, Yuling Li, Brian K. Coombes, Susantha Gomis, Kuldip K. Mirakhur, Andrew A. Potter, B. Brett Finlay
Publikováno v:
Infection and Immunity. 73:7161-7169
We have developed a novel ileal loop model for use in calves to analyze the contribution of Salmonella enterica serovar Typhimurium type III secretion systems to disease processes in vivo. Our model involves constructing ileal loops with end-to-end a
Autor:
Lorne A. Babiuk, A. K. Nichani, Hugh G.G. Townsend, Arthur M. Krieg, George Mutwiri, Jayaum S. Booth, Kuldip K. Mirakhur, M. Arshad Dar, Andrew A. Potter
Publikováno v:
Comparative immunology, microbiology and infectious diseases. 33(6)
Synthetic oligodeoxynucleotides (ODN) containing CpG motifs signal through TLR9 and activate innate immunity resulting in protection against a variety of parasitic, bacterial and viral pathogens in mouse models. However, few studies have demonstrated