Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kuldeep Lahry"'
Autor:
Sudhir Singh, Kuldeep Lahry, Chandra Sekhar Mandava, Jitendra Singh, Riyaz Ahmad Shah, Suparna Sanyal, Umesh Varshney
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 681-692 (2023)
Lamotrigine (Ltg), an anticonvulsant drug, targets initiation factor 2 (IF2), compromises ribosome biogenesis and causes toxicity to Escherichia coli. However, our understanding of Ltg toxicity in E. coli remains unclear. While our in vitro assays re
Externí odkaz:
https://doaj.org/article/56e200cc0fe04e10af7d172e7a9270b7
Publikováno v:
Journal of Molecular Biology. 432:5473-5488
One-carbon metabolism produces methionine and N10-formyl-tetrahydrofolate (N10-fTHF) required for aminoacylation and formylation of initiator tRNA (i-tRNA), respectively. In Escherichia coli, N10-fTHF is made from 5, 10-methylene-THF by a two-step re
Autor:
Kuldeep Lahry, Aiswarya Gopal, Amit Kumar Sahu, Carmelita Nora Marbaniang, Riyaz Ahmad Shah, Avani Mehta, Umesh Varshney
Publikováno v:
Journal of Molecular Biology. 434:167588
The fidelity of initiator tRNA (i-tRNA) selection in the ribosomal P-site is a key step in translation initiation. The highly conserved three consecutive G:C base pairs (3GC pairs) in the i-tRNA anticodon stem play a crucial role in its selective bin
Publikováno v:
Journal of molecular biology. 432(19)
One-carbon metabolism produces methionine and N
Publikováno v:
J Bacteriol
5,10-Methylenetetrahydrofolate reductase (MetF/MTHFR) is an essential enzyme in one-carbon metabolism forde novobiosynthesis of methionine. Ourin vivoandin vitroanalyses of MSMEG_6664/MSMEI_6484, annotated as putative MTHFR inMycobacterium smegmatis,
Autor:
Umesh Varshney, Shivjee Sah, Sudhir Singh, Riyaz Ahmad Shah, Rajagopal Varada, Kuldeep Lahry, Sunil Shetty
Publikováno v:
Nucleic Acids Research
Initiator tRNAs (i-tRNAs) possess highly conserved three consecutive GC base pairs (GC/GC/GC, 3GC pairs) in their anticodon stems. Additionally, in bacteria and eukaryotic organelles, the amino acid attached to i-tRNA is formylated by Fmt to facilita
Publikováno v:
IndraStra Global.
During protein synthesis, elongation factor G (EFG) participates at the steps of translocation and ribosome recycling. Fusidic acid (FA) is a bacteriostatic antibiotic, which traps EFG on ribosomes, stalling them on mRNAs. How the bacterial susceptib
Autor:
Umesh Varshney, Divya Dobriyal, Shreya Ahana Ayyub, Saikat Chakrabarti, Riyaz Ahmad Shah, Madhumita Bhattacharyya, Kuldeep Lahry, Souvik Bhattacharyya
Initiator tRNAs (i-tRNAs) are characterized by the presence of three consecutive GC base pairs (GC/GC/GC) in their anticodon stems in all domains of life. However, many mycoplasmas possess unconventional i-tRNAs wherein the highly conserved sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2886e3d4602571279af0c04542323b94