Zobrazeno 1 - 10
of 754
pro vyhledávání: '"Kulasinghe A"'
Autor:
Habib Sadeghirad, James Monkman, Chin Wee Tan, Ning Liu, Joseph Yunis, Meg L. Donovan, Afshin Moradi, Niyati Jhaveri, Chris Perry, Mark N. Adams, Ken O’Byrne, Majid E. Warkiani, Rahul Ladwa, Brett G.M. Hughes, Arutha Kulasinghe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) generally has a poor prognosis for patients with limited treatment options. While incorporating immune checkpoint inhibitors (ICIs) has now become the standard
Externí odkaz:
https://doaj.org/article/f1dddeab14594adbaeaca19710053a73
Autor:
Quan Zhou, Xueming Niu, Zhen Zhang, Kenneth O'Byrne, Arutha Kulasinghe, David Fielding, Andreas Möller, Alain Wuethrich, Richard J. Lobb, Matt Trau
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Glycosylation is the most common post‐translational modification of proteins and regulates a myriad of fundamental biological processes under normal, and pathological conditions. Altered protein glycosylation is linked to malignant transfo
Externí odkaz:
https://doaj.org/article/c3d887f40df3400f8461df112dc08352
Autor:
Meg L. Donovan, Niyati Jhaveri, Ning Ma, Bassem Ben Cheikh, James DeRosa, Ritu Mihani, Naomi Berrell, Jacky Y. Suen, James Monkman, John F. Fraser, Arutha Kulasinghe
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103226- (2024)
Summary: Single-cell spatial analysis of proteins is rapidly becoming increasingly important in revealing biological insights. Here, we present a protocol for automated high-plex multi-slide immunofluorescence staining and imaging of human head and n
Externí odkaz:
https://doaj.org/article/9a7d9e6b475d40c5a49c94dd441e8ff5
Autor:
James Monkman, Afshin Moradi, Joseph Yunis, Geoff Ivison, Aaron Mayer, Rahul Ladwa, Ken O’Byrne, Arutha Kulasinghe
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract The spatial localisation of immune cells within tumours are key to understand the intercellular communications that can dictate clinical outcomes. Here, we demonstrate an analysis pipeline for highly multiplexed CODEX data to phenotype and p
Externí odkaz:
https://doaj.org/article/5f104c6fa000442e8647ba9dd819e301
Autor:
Menéndez, Victoria, Solórzano, José L., García-Cosío, Mónica, Cereceda, Laura, Díaz, Eva, Estévez, Mónica, Roncador, Giovanna, Vega, Zaira, Montalbán, Carlos, Kulasinghe, Arutha, García, Juan F.
Publikováno v:
In Modern Pathology September 2024 37(9)
Autor:
Chin Wee Tan, Jinjin Chen, Ning Liu, Dharmesh D. Bhuva, Tony Blick, James Monkman, Caroline Cooper, Malvika Kharbanda, Kristen Feher, Belinda Phipson, Emily E. Killingbeck, Liuliu Pan, Youngmi Kim, Yan Liang, Andy Nam, Michael Leon, Paulo Souza-Fonseca-Guimaraes, Seigo Nagashima, Ana Paula Camargo Martins, Cleber Machado-Souza, Lucia de Noronha, Benjamin Tang, Kirsty Short, John Fraser, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Arutha Kulasinghe, Melissa J. Davis
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105016- (2024)
Summary: The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
Externí odkaz:
https://doaj.org/article/4f2fdb2f06f84144987d21c5de056820
Autor:
Soumyalekshmi Nair, Estefania Nova-Lamperti, Gonzalo Labarca, Arutha Kulasinghe, Kirsty R. Short, Flavio Carrión, Carlos Salomon
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract COVID-19 continues to affect an unprecedented number of people with the emergence of new variants posing a serious challenge to global health. There is an expansion of knowledge in understanding the pathogenesis of Coronavirus disease 2019 (
Externí odkaz:
https://doaj.org/article/0c26eacd001f4e4db55c9665c14ddd6b
Publikováno v:
In Current Opinion in Biotechnology April 2024 86
Autor:
Carney, Meagan, Pelaia, Tiana M, Chew, Tracy, Teoh, Sally, Phu, Amy, Kim, Karan, Wang, Ya, Iredell, Jonathan, Cirmena, Gabriella, Ballestrero, Alberto, Cripps, Allan, Cox, Amanda, De Maria, Andrea, Kulasinghe, Arutha, Feng, Carl, Chaussabel, Damien, Rinchai, Darawan, Bedognetti, Davide, Zoppoli, Gabriele, Gunawan, Gunawan, Thevarajan, Irani, Audsley, Jennifer, Eden, John-Sebastian, Kralovcova, Marcela, Nalos, Marek, Radic, Marko, Matejovic, Martin, Bedognetti, Michele, Prucha, Miroslav, Toufiq, Mohammed, Teluguakula, Narasaraju, West, Nicholas, Cremonesi, Paolo, Britton, Philip, Branco, Ricardo G, Bilyy, Rostyslav, MacDonald, Stephen, Karvunidis, Thomas, Kwan, Tim, Herwanto, Velma, Kuan, Win Sen, Zerbib, Yoann, McLean, Anthony, Schughart, Klaus, Tang, Benjamin, Shojaei, Maryam, Short, Kirsty R, Pelaia, Tiana Maria
Publikováno v:
In The Lancet Microbe March 2024 5(3):e272-e281
Publikováno v:
In Trends in Pharmacological Sciences February 2024 45(2):134-144