Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kulandaivelu Mahalingam"'
Publikováno v:
PeerJ, Vol 8, p e9755 (2020)
Background Gliomas are the most common and lethal type of intracranial tumors. With the current treatment regime, the median survival of patients with grade IV glioma (glioblastoma/GBM) remains at 14–16 months. RNA editing modifies the function and
Externí odkaz:
https://doaj.org/article/89b43089ad86448bbf596ff53e7c423e
Publikováno v:
PeerJ
PeerJ, Vol 8, p e9755 (2020)
PeerJ, Vol 8, p e9755 (2020)
Background Gliomas are the most common and lethal type of intracranial tumors. With the current treatment regime, the median survival of patients with grade IV glioma (glioblastoma/GBM) remains at 14–16 months. RNA editing modifies the function and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8b1654f5e660aea3976b4368abc710
http://europepmc.org/articles/PMC7531343
http://europepmc.org/articles/PMC7531343
Autor:
Kulandaivelu Mahalingam, Rajan Singh
Publikováno v:
Computational Biology and Chemistry. 67:122-130
The melanocortin-3-receptor (MC3R) is a novel gene candidate for human obesity, which involved in controlling the energy homeostasis and food intake behavior. The main aim behind this work is to investigate the potentially deleterious non-synonymous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e316ed93dcf22343af577ebc4d0dac5d
https://doi.org/10.1016/j.compbiolchem.2016.12.009
https://doi.org/10.1016/j.compbiolchem.2016.12.009
Publikováno v:
Comptes Rendus Biologies. 340:87-108
Obesity and its related health complications is a major problem worldwide. Hypothalamus and their signalling molecules play a critical role in the intervening and coordination with energy balance and homeostasis. Genetic factors play a crucial role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b0085be87c2093c58ccfff886a0a11
https://doi.org/10.1016/j.crvi.2016.11.007
https://doi.org/10.1016/j.crvi.2016.11.007
Publikováno v:
Oncotarget
// Shruti Bhargava 1, * , Vikas Patil 1, 2, * , Kulandaivelu Mahalingam 2 , Kumaravel Somasundaram 1 1 Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore-560012, India 2 Department of Bio-Medical Sciences, School of B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28eb76d7538e9b0c85eb4d51d35a9d1
https://doi.org/10.18632/oncotarget.14287
https://doi.org/10.18632/oncotarget.14287
Publikováno v:
International Journal of Human Genetics. 16:22-28
To correlate the association between heterochromatin variations and infertility in men, 70 infertile men (16 azoospermic men and 54 oligozoospermic men) and 35 fertile men were studied. Karyotype a...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90798cee34b9b6587801a6f5c1629323
https://doi.org/10.1080/09723757.2016.11886272
https://doi.org/10.1080/09723757.2016.11886272
Publikováno v:
3 Biotech. 8
Neuronal growth regulator 1 (NEGR1) is a candidate gene for human obesity, which encodes the neural cell adhesion and growth molecule. The aim of the current study was to recognize the non-synonymous SNPs (nsSNPs) with the highest predicted deleterio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0822bd4f725aad6012d5083abbd157
https://doi.org/10.1007/s13205-018-1463-0
https://doi.org/10.1007/s13205-018-1463-0
Autor:
Kulandaivelu Mahalingam, Vikas Patil
Publikováno v:
Gene. 679
Glioma is a wide category of brain tumor originates from glial cells. Lower-Grade Glioma (LGG) consists of World Health Organization (WHO) grade II and grade III gliomas. Since the LGGs can infiltrate into adjacent areas, the complete removal of tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42503882f7d8963f4ed0448a0a2b29a
https://pubmed.ncbi.nlm.nih.gov/30077762
https://pubmed.ncbi.nlm.nih.gov/30077762
Autor:
Vikas Patil, Baisakhi Mondal, Sannu Thomas, Arimappamagan Arivazhagan, Yashna Paul, Kumaravel Somasundaram, Naveen Kumar, Vani Santosh, Alangar S. Hegde, Kulandaivelu Mahalingam
Publikováno v:
Oncotarget
The major part of the genome that was previously called junk DNA has been shown to be dynamically transcribed to produce non-coding RNAs. Among them, the long non-coding RNAs (lncRNA) play diverse roles in the cellular context and are therefore invol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1364c76280198059c3738e10e01b96
https://pubmed.ncbi.nlm.nih.gov/30038703
https://pubmed.ncbi.nlm.nih.gov/30038703
Publikováno v:
International Journal of Human Genetics. 12:99-103
46, XY sex reversal condition is known to be caused by the point mutations or deletions in SRY gene at Yp11.3. Individuals with 46,XY status are phenotypically females with gonadal dysgenesis and poorly developed secondary sexual characters. In the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f83bec854f80a1cfe94456f4c266e9a
https://doi.org/10.1080/09723757.2012.11886169
https://doi.org/10.1080/09723757.2012.11886169