A Photo-responsive Small-Molecule Approach for the Opto-epigenetic Modulation of DNA Methylation.

Autor: Nguyen HP; Department of Chemistry, Institute for Structural and Molecular Biology, University College London, 20 Gordon Street, London, WC1H 0AJ, UK., Stewart S; UCL Cancer Institute, London, UK., Kukwikila MN; Department of Chemistry, Institute for Structural and Molecular Biology, University College London, 20 Gordon Street, London, WC1H 0AJ, UK., Jones SF; Department of Chemistry, Institute for Structural and Molecular Biology, University College London, 20 Gordon Street, London, WC1H 0AJ, UK., Offenbartl-Stiegert D; Department of Chemistry, Institute for Structural and Molecular Biology, University College London, 20 Gordon Street, London, WC1H 0AJ, UK., Mao S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.; Cancer Research (UK) Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, UK., Balasubramanian S; Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.; Cancer Research (UK) Cambridge Institute, University of Cambridge, Robinson Way, Cambridge, UK., Beck S; UCL Cancer Institute, London, UK., Howorka S; Department of Chemistry, Institute for Structural and Molecular Biology, University College London, 20 Gordon Street, London, WC1H 0AJ, UK.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2019 May 13; Vol. 58 (20), pp. 6620-6624. Date of Electronic Publication: 2019 Apr 12.