Levodopa Equivalent Daily Dosage: Geographical Variations and Real-Life Modules in Parkinson's Disease.

Autor: Kukkle PL; Parkinson's Disease and Movement Disorders Clinic, Bangalore, India., Kalia LV; Division of Neurology, Department of Medicine, Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.; Krembil Research Institute, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada., Habib A; Department of Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh., Jagota P; Chulalongkorn Centre of Excellence for Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand., Ojha R; Department of Neurology, Tribhuvan University Institute of Medicine, Kathmandu, Nepal., Kandadai RM; Parkinson's Disease and Movement Disorders Research Center, Citi Neuro Center, Hyderabad, India., Desai S; Shree Krishna Hospital Pramukhswami Medical College Bhaikaka University, Karamsad, India., Caldera M; Department of Neuroscience, Teaching Hospital Anuradhapura, Anuradhapura, Sri Lanka., Sirisena D; Colombo North Teaching Hospital Ragama, Ragama, Sri Lanka., Garg D; Department of Neurology, All India Institute of Medical Sciences, New Delhi, India., Mestre TA; Parkinson's Disease and Movement Disorders Center, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa Brain and Mind Institute, Ottawa, Ontario, Canada., Neupane R; Parkinson's Disease and Movement Disorders Clinic, Bangalore, India., Maytharakcheep S; Chulalongkorn Centre of Excellence for Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand., Sanyawut K; Chulalongkorn Centre of Excellence for Parkinson's Disease and Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand., Borgohain R; Parkinson's Disease and Movement Disorders Research Center, Citi Neuro Center, Hyderabad, India.

Publikováno v: Movement disorders clinical practice [Mov Disord Clin Pract] 2024 Nov; Vol. 11 (11), pp. 1388-1395. Date of Electronic Publication: 2024 Aug 31.

The Genetic Drivers of Juvenile, Young, and Early-Onset Parkinson's Disease in India.

Autor: Andrews SV; Denali Therapeutics, South San Francisco, California, USA., Kukkle PL; Manipal Hospital, Bangalore, India.; Parkinson's Disease and Movement Disorders Clinic, Bangalore, India., Menon R; MedGenome Labs Ltd, Bangalore, India., Geetha TS; MedGenome Labs Ltd, Bangalore, India., Goyal V; All India Institute of Medical Sciences (AIIMS), New Delhi, India.; Medanta Hospital, New Delhi, India.; Medanta, The Medicity, Gurgaon, India., Kandadai RM; Nizams Institute of Medical Sciences (NIMS), Hyderabad, India.; Citi Neuro Centre, Hyderabad, India., Kumar H; Institute of Neurosciences Kolkata, Kolkata, India., Borgohain R; Nizams Institute of Medical Sciences (NIMS), Hyderabad, India.; Citi Neuro Centre, Hyderabad, India., Mukherjee A; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Wadia PM; Jaslok Hospital and Research Centre, Mumbai, India., Yadav R; National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India., Desai S; Department of Neurology, Shree Krishna Hospital and Pramukhaswami Medical College, Bhaikaka University, Anand, India., Kumar N; All India Institute of Medical Sciences, Rishikesh, India.; All India Institute of Medical Sciences, Bibinagar (Hyderabad Metropolitan Region), Bibinagar, India., Joshi D; Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India., Murugan S; MedGenome Labs Ltd, Bangalore, India., Biswas A; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Pal PK; National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India., Oliver M; MedGenome Labs Ltd, Bangalore, India., Nair S; MedGenome Labs Ltd, Bangalore, India., Kayalvizhi A; MedGenome Labs Ltd, Bangalore, India., Samson PL; MedGenome Labs Ltd, Bangalore, India., Deshmukh M; MedGenome Labs Ltd, Bangalore, India., Bassi A; MedGenome Labs Ltd, Bangalore, India., Sandeep C; MedGenome Labs Ltd, Bangalore, India., Mandloi N; MedGenome Labs Ltd, Bangalore, India., Davis OB; Denali Therapeutics, South San Francisco, California, USA., Roberts MA; Denali Therapeutics, South San Francisco, California, USA., Leto DE; Denali Therapeutics, South San Francisco, California, USA., Henry AG; Denali Therapeutics, South San Francisco, California, USA., Di Paolo G; Denali Therapeutics, South San Francisco, California, USA., Muthane U; Parkinson and Ageing Research Foundation, Bangalore, India., Das SK; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Peterson AS; MedGenome Labs Ltd, Bangalore, India., Sandmann T; Denali Therapeutics, South San Francisco, California, USA., Gupta R; MedGenome Labs Ltd, Bangalore, India., Ramprasad VL; MedGenome Labs Ltd, Bangalore, India.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2024 Feb; Vol. 39 (2), pp. 339-349. Date of Electronic Publication: 2023 Nov 28.

Task-specific oromandibular dystonia secondary to chewing Khat (Catha edulis)- A series of 35 cases.

Autor: Wadia PM; Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India. Electronic address: pettarusp.wadia@gmail.com., Mathur V; Movement Disorder Clinic, Department of Neurology, Jaslok Hospital and Research Centre, Mumbai, India., Kukkle PL; Center for Parkinson's Disease and Movement Disorders Clinic, Manipal Hospital, Miller's Road, Bangalore, India; Parkinson's Disease and Movement Disorders Clinic, Bangalore, India., Khanna JN; Department of Dentistry, Jaslok Hospital and Research Centre, Mumbai, India.

Publikováno v: Parkinsonism & related disorders [Parkinsonism Relat Disord] 2023 Sep; Vol. 114, pp. 105806. Date of Electronic Publication: 2023 Aug 16.

Levodopa Dose Equivalency in Parkinson's Disease: Updated Systematic Review and Proposals.

Autor: Jost ST; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Kaldenbach MA; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Antonini A; Parkinson and Movement Disorders Unit, Department of Neurosciences (DNS), University of Padua, Padova, Italy., Martinez-Martin P; Center for Networked Biomedical Research in Neurodegenerative Diseases (CIBERNED), Carlos III Institute of Health, Madrid, Spain., Timmermann L; Department of Neurology, University Hospital Giessen and Marburg, Marburg, Germany., Odin P; Division of Neurology, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden., Katzenschlager R; Department of Neurology, Karl Landsteiner Institute for Neuroimmunological and Neurodegenerative Disorders at Klinik Donaustadt, Vienna, Austria., Borgohain R; Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India., Fasano A; Edmond J. Safra Program in Parkinson's Disease, Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital-University Health Network (UHN), Toronto, Ontario, Canada.; Division of Neurology, University of Toronto, Toronto, Ontario, Canada.; Krembil Research Institute, Toronto, Ontario, Canada.; Department of Parkinson's Disease & Movement Disorders Rehabilitation, Moriggia-Pelascini Hospital-Gravedona ed Uniti, Como, Italy., Stocchi F; University and Institute for Research and Medical Care IRCCS San Raffaele, Rome, Italy., Hattori N; Department of Neurology, Juntendo University Graduate School of Medicine, Tokyo, Japan., Kukkle PL; Center for Parkinson's Disease and Movement Disorders, Manipal Hospital, Bangalore, India.; Parkinson's Disease and Movement Disorders Clinic, Bangalore, India., Rodríguez-Violante M; Insituto Nacional de Neurologia y Neurocirugia, Movement Disorders Clinic, Mexico City, Mexico.; Movement Disorder Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico., Falup-Pecurariu C; Department of Neurology, Faculty of Medicine, Transilvania University of Brașov, Brașov, Romania.; Department of Neurology, County Emergency Clinic Hospital, Brașov, Romania., Schade S; Department of Clinical Neurophysiology, University Medical Center Göttingen, Göttingen, Germany., Petry-Schmelzer JN; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Metta V; Parkinson Foundation International Centre of Excellence, King's College Hospital, London, United Kingdom.; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom., Weintraub D; Departments of Psychiatry and Neurology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Parkinson's Disease Research, Education and Clinical Center (PADRECC), Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA., Deuschl G; Department of Neurology, University Hospital Schleswig-Holstein (UKSH), Christian-Albrechts-University Kiel, Kiel, Germany., Espay AJ; University of Cincinnati Gardner Neuroscience Institute, Gardner Family Center for Parkinson's Disease and Movement Disorders, Department of Neurology, University of Cincinnati, Cincinnati, Ohio, USA., Tan EK; Department of Neurology, National Neuroscience Institute, Singapore General Hospital, Singapore, Singapore.; Neuroscience and Behavioral Disorders (NBD) Department, Duke-NUS Medical School, Singapore, Singapore., Bhidayasiri R; Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.; The Academy of Science, The Royal Society of Thailand, Bangkok, Thailand., Fung VSC; Movement Disorder Unit, Department of Neurology, Westmead Hospital, Westmead, Australia., Cardoso F; Movement Disorders Unit, Internal Medicine Department, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil., Trenkwalder C; Paracelsus-Elena-Klinik, Kassel, Germany.; Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Jenner P; Institute of Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom., Ray Chaudhuri K; Parkinson Foundation International Centre of Excellence, King's College Hospital, London, United Kingdom.; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.; NIHR Mental Health Biomedical Research Centre and Dementia Biomedical Research Unit, South London and Maudsley NHS Foundation Trust and King's College London, London, United Kingdom., Dafsari HS; Department of Neurology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.

Publikováno v: Movement disorders : official journal of the Movement Disorder Society [Mov Disord] 2023 Jul; Vol. 38 (7), pp. 1236-1252. Date of Electronic Publication: 2023 May 05.

South Asian medical cohorts reveal strong founder effects and high rates of homozygosity.

Autor: Wall JD; Institute for Human Genetics, University of California, San Francisco, CA, 94143, USA. jeffwall.genetics@gmail.com.; Dept of Ornithology and Mammology, California Academy of Sciences, San Francisco, CA, 94118, USA. jeffwall.genetics@gmail.com., Sathirapongsasuti JF; MedGenome Inc., Foster City, CA, 94404, USA.; GenomeAsia 100K Foundation, Foster City, CA, 94404, USA., Gupta R; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Rasheed A; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Venkatesan R; Madras Diabetes Research Foundation and Dr. Mohan's Diabetes Specialties Centre, Chennai, Tamil Nadu, 600086, India., Belsare S; Institute for Human Genetics, University of California, San Francisco, CA, 94143, USA., Menon R; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Phalke S; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Mittal A; Thermo Fisher Scientific, Santa Clara, CA, 95051, USA., Fang J; Thermo Fisher Scientific, Santa Clara, CA, 95051, USA., Tanneeru D; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Deshmukh M; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Bassi A; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Robinson J; Institute for Human Genetics, University of California, San Francisco, CA, 94143, USA., Chaudhary R; MedGenome Inc., Foster City, CA, 94404, USA., Murugan S; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Ul-Asar Z; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Saleem I; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Ishtiaq U; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Fatima A; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Sheikh SS; Punjab Institute of Cardiology, Lahore, Pakistan., Hameed S; Punjab Institute of Cardiology, Lahore, Pakistan., Ishaq M; Karachi Institute of Heart Diseases, Karachi, Pakistan., Rasheed SZ; Karachi Institute of Heart Diseases, Karachi, Pakistan., Memon FU; Red Crescent Institute of Cardiology, Hyderabad, Pakistan., Jalal A; Faisalabad Institute of Cardiology, Faisalabad, Pakistan., Abbas S; Faisalabad Institute of Cardiology, Faisalabad, Pakistan., Frossard P; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan., Fuchsberger C; Department of Biostatistics, University of Michigan, Ann Arbor, MI, 48109, USA.; Institute for Biomedicine, Eurac Research, Bolzano, Italy.; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Forer L; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Schoenherr S; Institute of Genetic Epidemiology, Department of Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Bei Q; Department of Molecular Biology, Genentech, South San Francisco, CA, 94080, USA., Bhangale T; Department of Human Genetics, Genentech, South San Francisco, CA, 94080, USA., Tom J; Product Development Data Sciences, Genentech, South San Francisco, CA, 94080, USA., Gadde SGK; Narayana Nethralaya Foundation, Bengaluru, Karnataka, 560010, India., B V P; Narayana Nethralaya Foundation, Bengaluru, Karnataka, 560010, India., Naik NK; Narayana Nethralaya Foundation, Bengaluru, Karnataka, 560010, India., Wang M; Program in Medical and Population Genetics & Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Kwok PY; Institute for Human Genetics, University of California, San Francisco, CA, 94143, USA.; Cardiovascular Research Institute and Department of Dermatology, University of California San Francisco, San Francisco, CA, 94143, USA.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Khera AV; Harvard Medical School, Boston, MA, 02115, USA.; Division of Cardiology, Department of Medicine, Brigham and Women's Hospital, MA, 02115, Boston, USA.; Verve Therapeutics, Cambridge, MA, 02139, USA., Lakshmi BR; MDCRC, Royal Care Super Speciality Hospital 1/520, Neelambur, Coimbatore, Tamil Nadu, 641062, India., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Chowdhury R; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, UK., di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, University of Cambridge, Cambridge, UK.; National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK., Naheed A; Initiative for Non Communicable Diseases, Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh., Goyal V; All India Institute of Medical Sciences (AIIMS), New Delhi, India.; Medanta Hospital, New Delhi, India.; Medanta, The Medicity, Gurgaon, India., Kandadai RM; Nizams Institute of Medical Sciences (NIMS), Hyderabad, India., Kumar H; Institute of Neurosciences Kolkata, Kolkata, India., Borgohain R; Nizams Institute of Medical Sciences (NIMS), Hyderabad, India., Mukherjee A; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Wadia PM; Jaslok Hospital and Research Centre, Mumbai, India., Yadav R; National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India., Desai S; Shree Krishna Hospital and Pramukhaswami Medical College, Bhaikaka University, Karamsad, Gujarat, India., Kumar N; All India Institute of Medical Sciences, Rishikesh, India., Biswas A; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Pal PK; National Institute of Mental Health and Neurosciences (NIMHANS), Bengaluru, India., Muthane UB; Parkinson and Ageing Research Foundation, Bengaluru, India., Das SK; Bangur Institute of Neurosciences and Institute of Post Graduate Medical Education and Research (IPGME&R), Kolkata, India., Ramprasad VL; MedGenome Labs Pvt. Ltd., Bengaluru, Karnataka, 560099, India., Kukkle PL; All India Institute of Medical Sciences, Rishikesh, India.; Manipal Hospital, Miller Road, Bengaluru, India.; Parkinson's Disease and Movement Disorders Clinic, Bengaluru, India., Seshagiri S; GenomeAsia 100K Foundation, Foster City, CA, 94404, USA.; Department of Molecular Biology, Genentech, South San Francisco, CA, 94080, USA., Kathiresan S; Program in Medical and Population Genetics & Cardiovascular Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Verve Therapeutics, Cambridge, MA, 02139, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA., Ghosh A; Narayana Nethralaya Foundation, Bengaluru, Karnataka, 560010, India., Mohan V; Madras Diabetes Research Foundation and Dr. Mohan's Diabetes Specialties Centre, Chennai, Tamil Nadu, 600086, India., Saleheen D; Center for Non-Communicable Disease, Karachi, Karachi City, Sindh, 75300, Pakistan.; Seymour, Paul and Gloria Milstein Division of Cardiology at Columbia University, New York, NY, 10032, USA., Stawiski EW; MedGenome Inc., Foster City, CA, 94404, USA.; GenomeAsia 100K Foundation, Foster City, CA, 94404, USA.; Department of Molecular Biology, Genentech, South San Francisco, CA, 94080, USA.; Caribou Biosciences, Berkeley, CA, 94710, USA., Peterson AS; MedGenome Inc., Foster City, CA, 94404, USA. peterson.andrew@genomeasia100k.org.; GenomeAsia 100K Foundation, Foster City, CA, 94404, USA. peterson.andrew@genomeasia100k.org.; Department of Molecular Biology, Genentech, South San Francisco, CA, 94080, USA. peterson.andrew@genomeasia100k.org.; Broadwing Bio, South San Francisco, CA, 94080, USA. peterson.andrew@genomeasia100k.org.

Publikováno v: Nature communications [Nat Commun] 2023 Jun 08; Vol. 14 (1), pp. 3377. Date of Electronic Publication: 2023 Jun 08.