Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Kuiying Xu"'
Autor:
Chia-Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan Gallagher, Kuiying Xu, Hsiaoju Lee, Shihong Li, Meagan J. McManus, Robert H. Mach
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-9 (2023)
Externí odkaz:
https://doaj.org/article/993d43f6deb4414c8a047530c4269507
Autor:
Mehran Makvandi, Minu Samanta, Paul Martorano, Hwan Lee, Sarah B. Gitto, Khushbu Patel, David Groff, Jennifer Pogoriler, Daniel Martinez, Aladdin Riad, Hannah Dabagian, Michael Zaleski, Tara Taghvaee, Kuiying Xu, Ji Youn Lee, Catherine Hou, Alvin Farrel, Vandana Batra, Sean D. Carlin, Daniel J. Powell, Robert H. Mach, Daniel A. Pryma, John M. Maris
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
The efficacy and toxicity of the PARP inhibitor parthanatine, radiolabeled with the alpha particle emitter astatine-211, in 11 patient derived neuroblastoma murine xenografts is investigated.
Externí odkaz:
https://doaj.org/article/39307010894b498daf099e0526685b72
Autor:
Chia-Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan Gallagher, Kuiying Xu, Hsiaoju Lee, Shihong Li, Meagan J. McManus, Robert H. Mach
Publikováno v:
EJNMMI Research, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Oxidative stress is implicated in the pathogenesis of the most common neurodegenerative diseases, such as Alzheimer’s disease (AD). However, tracking oxidative stress in the brain has proven difficult and impeded its use as a bi
Externí odkaz:
https://doaj.org/article/a3b82024f10c4b7c8060ea62d1e48ada
Autor:
Chi-Chang Weng, Aladdin Riad, Brian P. Lieberman, Kuiying Xu, Xin Peng, John L. Mikitsh, Robert H. Mach
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1564 (2022)
The sigma-2 receptor/transmembrane protein 97 (σ2R/TMRM97) is a promising biomarker of tumor proliferation and a target for cancer therapy. [3H]DTG has been used to evaluate σ2R/TMEM97 binding affinity in compound development studies. However, [3H]
Externí odkaz:
https://doaj.org/article/7cedcec302664a0ea9e4d9fb10badc65
Autor:
Robert K. Doot, Jacob G. Dubroff, Joshua S. Scheuermann, Kyle J. Labban, Jenny Cai, Chia-Ju Hsieh, Shihong Li, Hsiaoju Lee, Erin K. Schubert, Catherine Hou, Regan Sheffer, Alexander Schmitz, Kuiying Xu, Robert H. Mach
Publikováno v:
EJNMMI Physics, Vol 5, Iss 1, Pp 1-12 (2018)
Abstract Background [18F]Fluortriopride (FTP) was developed as a dopamine D3-selective radiotracer, thought to be important to neurobiological reward pathways and implicated in drug addiction, Parkinson’s disease, and schizophrenia. Preclinical rad
Externí odkaz:
https://doaj.org/article/c889333eed8045fbbd7ee7a3be611495
Autor:
Chia-Ju Hsieh, Kuiying Xu, Iljung Lee, Thomas J. A. Graham, Zhude Tu, Dhruva Dhavale, Paul Kotzbauer, Robert H. Mach
Publikováno v:
ACS Omega, Vol 3, Iss 4, Pp 4486-4493 (2018)
Externí odkaz:
https://doaj.org/article/3f791d05b61544b8ad2bcf5486bb3eb7
Autor:
Chia-Ju Hsieh, Aladdin Riad, Ji Youn Lee, Kristoffer Sahlholm, Kuiying Xu, Robert R. Luedtke, Robert H. Mach
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 529 (2021)
[18F]Fallypride and [18F]Fluortriopride (FTP) are two different PET radiotracers that bind with sub-nanomolar affinity to the dopamine D3 receptor (D3R). In spite of their similar D3 affinities, the two PET ligands display very different properties f
Externí odkaz:
https://doaj.org/article/2e5b88a837b14c0093266e4b72355756
Autor:
Aladdin Riad, Sarah B. Gitto, Hwan Lee, Harrison D. Winters, Paul M. Martorano, Chia-Ju Hsieh, Kuiying Xu, Dalia K. Omran, Daniel J. Powell, Robert H. Mach, Mehran Makvandi
Publikováno v:
Molecules, Vol 25, Iss 24, p 6029 (2020)
Theranostics are emerging as a pillar of cancer therapy that enable the use of single molecule constructs for diagnostic and therapeutic application. As poly adenosine diphosphate (ADP)-ribose polymerase 1 (PARP-1) is overexpressed in various cancer
Externí odkaz:
https://doaj.org/article/b19eeee553f44673aeba1a3c881f1123
Autor:
Daniel A. Pryma, John M. Maris, Robert H. Mach, Bruce R. Pawel, Roger A. Greenberg, Sean D. Carlin, Kuiying Xu, Daniel Martinez, Pichai Raman, Catherine Hou, Ho Sze Chan, Chi-Chang Weng, Komal S. Rathi, Sean W. Reilly, Laura N. Puentes, Hwan Lee, Mehran Makvandi
SI Figure 1: Reaction scheme for synthesizing 1-(4-astatophenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one ([211At]MM4) from tin precursor 1-(4-(tributylstannyl)phenyl)-8,9-dihydro-2,7,9a-triazabenzo[cd]azulen-6(7H)-one; SI Figure 2: Reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119714469e6f6f337985a31a1b82ffd9
https://doi.org/10.1158/1535-7163.22506018
https://doi.org/10.1158/1535-7163.22506018
Autor:
Robert H. Mach, Roger A. Greenberg, Daniel A. Pryma, Elizabeth S. McDonald, Chenbo Zeng, Harrison D. Winters, Samuel Sander Effron, Redmond-Craig Anderson, Brian P. Lieberman, Kuiying Xu, Mehran Makvandi
Legends for supplemental figures and tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c30b588c9eedb16a05efc9e7d0572e0
https://doi.org/10.1158/0008-5472.22411044
https://doi.org/10.1158/0008-5472.22411044