Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Kuisheng, Chen"'
Autor:
Chenbo Yang, Jiao Shu, Yiwei Li, Na Zhao, Xiaonan Liu, Xiangyu Tian, Zexin Sun, Muhammad Saud Tabish, Yichen Hong, Kuisheng Chen, Miaomiao Sun
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The proliferation of tumors is not merely self-regulated by the cancer cells but is also intrinsically connected to the tumor microenvironment (TME). Within this complex TME, cancer-associated fibroblasts (CAFs) are pivotal in the modulation of tumor
Externí odkaz:
https://doaj.org/article/45bdca9de1f6496f96c076261aa6ae2b
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Rationale Cancer of unknown primary (CUP) is a group of rare malignancies with poor prognosis and unidentifiable tissue-of-origin. Distinct DNA methylation patterns in different tissues and cancer types enable the identification of the tissu
Externí odkaz:
https://doaj.org/article/fc7bc869f7314ab6acceb7e9834cd502
Autor:
Chao Chen, Chenbo Yang, Xiangyu Tian, Yinghao Liang, Shuaiyuan Wang, Xiaoqian Wang, Yuwei Shou, Hui Li, Qiankun Xiao, Jiao Shu, Miaomiao Sun, Kuisheng Chen
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 14468-14483 (2023)
Abstract Background Esophageal squamous cell carcinoma (ESCC), an aggressive gastrointestinal tumor, often has high early lymphatic metastatic potential. Cancer‐associated fibroblasts (CAFs) are primary components in tumor microenvironment (TME), a
Externí odkaz:
https://doaj.org/article/dd50b8992f6c496ab0a741d841a161da
Publikováno v:
Pathology and Oncology Research, Vol 29 (2023)
Despite significant advances in the diagnosis and treatment of esophageal squamous cell carcinoma (ESCC), esophageal cancer is still a heavy social and medical burden due to its high incidence. Uncontrolled division and proliferation is one of the ch
Externí odkaz:
https://doaj.org/article/44a3dff1ee2d4615a502328ae1dcb697
Autor:
Yuwei Shou, Xiaoqian Wang, Chao Chen, Yinghao Liang, Chenbo Yang, Qiankun Xiao, Hui Li, Shuaiyuan Wang, Jiao Shu, Xiangyu Tian, Kuisheng Chen
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-15 (2022)
Abstract Background Growing evidence has indicated that tumor-associated macrophages (TAMs) promote tumor angiogenesis. However, the mechanisms underlying the pro-angiogenic switch of TAMs remains unclear. Here, we examined how exosomal miR-301a-3p s
Externí odkaz:
https://doaj.org/article/01a1fca2b98f464b95e6b5b3efa3f072
Autor:
Shuaiyuan Wang, Yinghao Liang, Jiaxin Zhang, Wenjia Wang, Yichen Hong, Miaomiao Sun, Jiao Shu, Kuisheng Chen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Esophageal squamous cell carcinomas (ESCC) is an aggressive disease with five-year overall survival (OS)
Externí odkaz:
https://doaj.org/article/4322b6086e5142f9a89985ce9db34bc0
Autor:
Maletsooa Story Chabeli, Xiaoqian Wang, Liang Yinghao, Chao Chen, Chenbo Yang, Yuwei Shou, Shuaiyuan Wang, Kuisheng Chen
Publikováno v:
Cancer Treatment and Research Communications, Vol 32, Iss , Pp 100621- (2022)
In cancer, tumor-associated macrophages (TAMs) possess crucial functions in facilitating epithelial-mesenchymal transition (EMT). EMT is a crucial process in tumor metastasis. Tumor metastasis is one of the hallmarks of cancer and leads to patient mo
Externí odkaz:
https://doaj.org/article/cb14cb4a6daf4f429b99b963d16888f4
Autor:
Chenbo Yang, Chao Chen, Qiankun Xiao, Xiaoqian Wang, Yuwei Shou, Xiangyu Tian, Shuaiyuan Wang, Hui Li, Yinghao Liang, Jiao Shu, Kuisheng Chen, Miaomiao Sun
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Esophageal squamous cell carcinoma (ESCC) has high morbidity and mortality rates owing to its ability to infiltrate and metastasize. Microvessels formed in early-stage ESCC promote metastasis. Phosphatase and tensin homolog (PTEN) mediates macrophage
Externí odkaz:
https://doaj.org/article/aeba3514e0bc47da973d9c74064d4502
Autor:
Junmei Hao, Yan Lyu, Jiarui Zou, Yunyun Zhang, Shuishan Xie, Lili Jing, Fangrong Tang, Jiahong Lyu, Wenfeng Zhang, Jianbo Zhang, Xunting Wang, Kuisheng Chen, Jiandi Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundImmunohistochemistry (IHC)-based surrogate assay is the prevailing method in daily clinical practice to determine the necessity of chemotherapy for Luminal-like breast cancer patients worldwide. It relies on Ki67 scores to separate Luminal
Externí odkaz:
https://doaj.org/article/e82aec88a4024376800762dc0f96613e
Publikováno v:
Iranian Journal of Immunology, Vol 16, Iss 3, Pp 190-199 (2019)
Background: Macrophage polarization plays a critical role in determining the inflammatory states. Hepcidin is a key negative regulator of iron homeostasis and functions. Although hepcidin has been shown to affect ferroportin expression in macrophages
Externí odkaz:
https://doaj.org/article/8ecee67069b44be797b3bb7d2c310aed