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Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk

Autor: Kuiper, Lieke M, Polinder-Bos, Harmke A, Bizzarri, Daniele, Vojinovic, Dina, Vallerga, Costanza L, Beekman, Marian, Dollé, Martijn E T, Ghanbari, Mohsen, Voortman, Trudy, Reinders, Marcel J T, Verschuren, W M Monique, Slagboom, P Eline, van den Akker, Erik B, van Meurs, Joyce B J

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::c155b5aea3f13c4428cbadda426956e5
http://hdl.handle.net/10029/626778

Additional file 1 of C-factor: a summary measure for systemic arterial calcifications

Autor: Kuiper, Lieke M., Ikram, M. Kamran, Kavousi, Maryam, Vernooij, Meike W., Ikram, M. Arfan, Bos, Daniel

Additional file 1: Table S1. Sensitivity analysis: creating a sex-specific C-factor. A multi-page table displaying the loadings of the different vessel beds included in the C-factors when composed based on the entire population, and when only the men

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6ef8c33c8606fd75fa92ee7d66d194

Longitudinal change in mitochondrial heteroplasmy exhibits positive selection for deleterious variants.

Autor: Kuiper LM; Genetic Laboratory, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Shi W; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Verlouw J; Genetic Laboratory, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Hong YS; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Arp P; Genetic Laboratory, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Puiu D; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Broer L; Genetic Laboratory, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Xie J; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Newcomb C; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Bader JS; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Guallar E; Department of Epidemiology and Medicine, and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University Bloomberg School of Public Health. Baltimore, MD, USA., van Meurs JBJ; Genetic Laboratory, Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Orthopeadics & Sports Medicine, Erasmus MC, Rotterdam, the Netherlands., Arking DE; McKusick-Nathans Institute, Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Apr 03. Date of Electronic Publication: 2024 Apr 03.