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pro vyhledávání: '"Kuida Chen"'
Autor:
Kuida Chen, Tianqi Xu, Dangdang Li, Jialiang Li, Ke Shi, Jingru Hu, Guangyue Li, Guangchao Sui, Tianxin Li, Kazushi Inoue
Publikováno v:
International Journal of Oncology
The cyclin D binding myb‑like transcription factor 1 (DMTF1), a haplo‑insufficient tumor suppressor gene, has 3 alternatively spliced mRNA isoforms encoding DMTF1α, β and γ proteins. Previous studies have indicated a tumor suppressive role of
Publikováno v:
FEBS letters. 593(12)
As a transcription factor, Yin Yang 1 (YY1) either activates or represses gene expression depending on its recruited cofactors. The YY1 C-terminal consists of four zinc fingers (ZF) that are responsible for its DNA binding. However, the contribution