Antiproliferative and proapoptotic effects of a pyrrole containing arylthioindole in human Jurkat leukemia cell line and multidrug-resistant Jurkat/A4 cells.

Autor: Philchenkov AA; a R. E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology; National Academy of Sciences of Ukraine ; Kyiv , Ukraine., Zavelevich MP; a R. E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology; National Academy of Sciences of Ukraine ; Kyiv , Ukraine., Tryndyak VP; b Division of Biochemical Toxicology; National Center for Toxicological Research ; Jefferson , AR USA., Kuiava LM; a R. E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology; National Academy of Sciences of Ukraine ; Kyiv , Ukraine., Blokhin DY; c N. N. Blokhin Cancer Research Center ; Moscow , Russian Federation., Miura K; d Miyagi Cancer Center ; Natori , Japan., Silvestri R; e Istituto Pasteur-Fondazione Cenci Bolognetti; Sapienza Università di Roma ; Roma , Italy., Pogribny IP; b Division of Biochemical Toxicology; National Center for Toxicological Research ; Jefferson , AR USA.

Publikováno v: Cancer biology & therapy [Cancer Biol Ther] 2015; Vol. 16 (12), pp. 1820-9.

Synthesis and antiproliferative activity of conformationally restricted 1,2,3-triazole analogues of combretastatins in the sea urchin embryo model and against human cancer cell lines.

Autor: Demchuk DV; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: demchuk@ioc.ac.ru., Samet AV; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: sametav@ioc.ac.ru., Chernysheva NB; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: info@chemblock.com., Ushkarov VI; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: ushkarov@inbox.ru., Stashina GA; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: galina_stashina@chemical-block.com., Konyushkin LD; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: LeonidK@chemical-block.com., Raihstat MM; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation; Chemical Block Ltd, 3 Kyriacou Matsi, 3723 Limassol, Cyprus. Electronic address: mr@chemical-block.com., Firgang SI; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation. Electronic address: cbi@chemical-block.com., Philchenkov AA; R.E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasyl'kivska Street, 03022 Kyiv, Ukraine. Electronic address: a_philch@onconet.kiev.ua., Zavelevich MP; R.E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasyl'kivska Street, 03022 Kyiv, Ukraine. Electronic address: butenko@onconet.kiev.ua., Kuiava LM; R.E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasyl'kivska Street, 03022 Kyiv, Ukraine. Electronic address: kuyavalm@ukr.net., Chekhun VF; R.E. Kavetsky Institute of Experimental Oncology, Pathology and Radiobiology, National Academy of Sciences of Ukraine, 45 Vasyl'kivska Street, 03022 Kyiv, Ukraine. Electronic address: chekhun@onconet.kiev.ua., Blokhin DY; Department of Biological and Medicinal Chemistry, Moscow Institute of Physics and Technology, Institutsky Per. 9, Dolgoprudny, Moscow Region, 141700, Russia. Electronic address: blokhin@yandex.ru., Kiselyov AS; ChemDiv, 6605 Nancy Ridge Drive, San Diego, CA 92121, USA. Electronic address: akiselyov@chemdiv.com., Semenova MN; Chemical Block Ltd, 3 Kyriacou Matsi, 3723 Limassol, Cyprus; N.K. Kol'tsov Institute of Developmental Biology RAS, 26 Vavilov Street, 119334 Moscow, Russian Federation. Electronic address: ms@chemical-block.com., Semenov VV; N.D. Zelinsky Institute of Organic Chemistry RAS, 47 Leninsky Prospect, 119991 Moscow, Russian Federation; Chemical Block Ltd, 3 Kyriacou Matsi, 3723 Limassol, Cyprus. Electronic address: vs@zelinsky.ru.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2014 Jan 15; Vol. 22 (2), pp. 738-55. Date of Electronic Publication: 2013 Dec 12.