Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Kui-Ming Chan"'
Autor:
Su Zhang, Yang Meng, Lian Zhou, Lei Qiu, Heping Wang, Dan Su, Bo Zhang, Kui‐Ming Chan, Junhong Han
Publikováno v:
MedComm, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract Emerging evidence indicates that resolution of inflammation is a critical and dynamic endogenous process for host tissues defending against external invasive pathogens or internal tissue injury. It has long been known that autoimmune disease
Externí odkaz:
https://doaj.org/article/e8cfd7873f9142af9b74c3a1cfa6db65
Autor:
Huiqi Tan, Mia Xinfang Miao, Rylee Xu Luo, Joan So, Lei Peng, Xiaoxuan Zhu, Eva Hin Wa Leung, Lina Zhu, Kui Ming Chan, Martin Cheung, Siu Yuen Chan
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Nucleosome assembly proteins (NAPs) have been identified as histone chaperons. Testis‐Specific Protein, Y‐Encoded‐Like (TSPYL) is a newly arisen NAP family in mammals. TSPYL2 can be transcriptionally induced by DNA damage and TGFβ cau
Externí odkaz:
https://doaj.org/article/5b11482ae15f4614abc925667ecbfef7
Autor:
Xuanming Guo, Pallavi Asthana, Lixiang Zhai, Ka Wing Cheng, Susma Gurung, Jiangang Huang, Jiayan Wu, Yijing Zhang, Arun Kumar Mahato, Mart Saarma, Mart Ustav, Hiu Yee Kwan, Aiping Lyu, Kui Ming Chan, Pingyi Xu, Zhao-Xiang Bian, Hoi Leong Xavier Wong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an ongoing need to identify safe and tolerable therapeutics for obesity management. Here
Externí odkaz:
https://doaj.org/article/a29cc025e9664a529d8c924433238848
Autor:
Huazhang Zhu, Dawei Wang, Zuodong Ye, Lihong Huang, Wenjie Wei, Kui Ming Chan, Rongxin Zhang, Liang Zhang, Jianbo Yue
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Many viruses enter host cells by hijacking endosomal trafficking. CapZ, a canonical actin capping protein, participates in endosomal trafficking, yet its precise role in endocytosis and virus infection remains elusive. Results Her
Externí odkaz:
https://doaj.org/article/8e664f916c61404889caad51f17ef210
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9699 (2024)
Histone variants are the paralogs of core histones (H2A, H2B, H3 and H4). They are stably expressed throughout the cell cycle in a replication-independent fashion and are capable of replacing canonical counterparts under different fundamental biologi
Externí odkaz:
https://doaj.org/article/c4a95ad09a13477a839546945f1a60c6
Autor:
Po Man Lai, Kui Ming Chan
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3144 (2024)
Histones are nuclear proteins essential for packaging genomic DNA and epigenetic gene regulation. Paralogs that can substitute core histones (H2A, H2B, H3, and H4), named histone variants, are constitutively expressed in a replication-independent man
Externí odkaz:
https://doaj.org/article/ac8c150bf75946b18ab2d2fb9c701d5c
Autor:
Hao Huang, Jianyang Hu, Alishba Maryam, Qinghua Huang, Yuchen Zhang, Saravanan Ramakrishnan, Jingyu Li, Haiying Ma, Victor W. S. Ma, Wah Cheuk, Grace Y. K. So, Wei Wang, William C. S. Cho, Liang Zhang, Kui Ming Chan, Xin Wang, Y. Rebecca Chin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with poor prognostic outcomes. Here the authors characterize super-enhancer heterogeneity and they identify genes that are specifically regulated by TNBC-specific super-enhan
Externí odkaz:
https://doaj.org/article/abbe2a31ae264afda36fe681ddcc9d63
Autor:
Congcong Tian, Qin Zhang, Jing Jia, Jiaqi Zhou, Ziwei Zhang, Karri, Srinivasu, Jiuhang Jiang, Dickinson, Quinn, Yuan Yao, Xiaorong Tang, Yuxin Huang, Ting Guo, Ziwei He, Zheng Liu, Yuan Gao, Xinran Yang, Yuchun Wu, Kui Ming Chan, Daoqin Zhang, Junhong Han
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/14/2024, Vol. 121 Issue 20, p1-9, 21p
Autor:
William C. Cho, C Geoffrey Lau, Kui Ming Chan, Grace Y. K. So, Liang Zhang, Hao Huang, Xin Wang, Saravanan Ramakrishnan, Victor W.S. Ma, Jianyang Hu, Qingling He, Wah Cheuk, Y. Rebecca Chin, Yilin Pan, Yuni Lai
Publikováno v:
British Journal of Cancer
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with poor prognosis. By performing multiomic profiling, we recently uncovered super-enhancer heterogeneity between breast cancer subtypes. Our data also reveale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8839fb17bbef54f72d4c376142a3ca
https://doi.org/10.1038/s41416-021-01596-3
https://doi.org/10.1038/s41416-021-01596-3
Autor:
Lixiang Zhai, Chunhua Huang, Ziwan Ning, Yijing Zhang, Min Zhuang, Wei Yang, Xiaolei Wang, Jingjing Wang, Eric Lu Zhang, Haitao Xiao, Ling Zhao, Yan Y Lam, Chi-Fung Willis Chow, Jiandong Huang, Shuofeng Yuan, Kui-Ming Chan, Chun-Su Yuan, Johnson Yiu-Nam Lau, Hoi-Leong Xavier Wong, Zhao-Xiang Bian
Publikováno v:
Basic Gastroenterology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b30b35b876b468c846b261e34d77da6b
https://doi.org/10.1136/gutjnl-2022-iddf.36
https://doi.org/10.1136/gutjnl-2022-iddf.36