Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kui-Hao Chen"'
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The natural flavone acacetin inhibits several voltage-gated potassium currents in atrial myocytes, and has anti-atrial fibrillation (AF) effect in experimental AF models. The present study investigates whether acacetin inhibits the Ca2+-activated pot
Externí odkaz:
https://doaj.org/article/4d5c085ac3254f2f9490651152d30ccf
Autor:
Xiao-Hui Xu, Hai-Ying Sun, Yan-Hui Zhang, Wei Wu, Kui-Hao Chen, Yi Liu, Chun-Yu Deng, Xi-Yong Yu, Man-Wen Jin, Gui-Rong Li
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51550 (2012)
Allitridi (diallyl trisulfide) is an active compound (volatile oil) from garlic. The previous studies reported that allitridi had anti-arrhythmic effect. The potential ionic mechanisms are, however, not understood. The present study was designed to d
Externí odkaz:
https://doaj.org/article/94ec8f6e397949cebf22472c9268831f
Autor:
Yan Wang, Xiao-Hui Xu, Kui-Hao Chen, Man-Wen Jin, Gui-Rong Li, Hui Liu, Lei Yang, Guo-Sheng Xiao, Hai-Ying Sun, Xin-Ling Du
Publikováno v:
Heart Rhythm. 13:762-770
Background Several mammalian species display distinct biophysical properties between atrial and ventricular voltage-gated sodium current (I Na ); however, the potential mechanism behind this phenomenon is unknown. Objective The purpose of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::713d1885d5e23d68292a5a4f02453df1
https://doi.org/10.1016/j.hrthm.2015.11.022
https://doi.org/10.1016/j.hrthm.2015.11.022
Autor:
Gui-Rong Li, Lei Yang, Guo-Sheng Xiao, Yan Wang, Kui-Hao Chen, Man-Wen Jin, Hui Liu, Hai-Ying Sun
Publikováno v:
Pharmacological Research. 104:61-69
SKF-96365 is a TRPC channel antagonist commonly used to characterize the potential functions of TRPC channels in different systems, which was recently reported to induce QTc prolongation on ECG by inhibiting TRPC channels. The present study investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c7ea96757df12d7d63f747b0c82f71
https://doi.org/10.1016/j.phrs.2015.12.012
https://doi.org/10.1016/j.phrs.2015.12.012
Autor:
Feng Lin, Hui-Jun Wu, Hai-Ying Sun, Kui-Hao Chen, Gui-Rong Li, Lei Yang, Guo-Sheng Xiao, Hui Liu, Gang Li, Yan Wang
Publikováno v:
Scientific Reports
The morbidity and mortality of patients with ischemic cardiomyopathy resulted from ischemia/reperfusion injury are very high. The present study investigates whether our previously synthesized water-soluble phosphate prodrug of acacetin was cardioprot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa91a36a7622855d8aa4f341590e9181
https://doi.org/10.1038/srep36435
https://doi.org/10.1038/srep36435
Publikováno v:
Pflugers Archiv : European journal of physiology. 467(6)
SKF-96365 (1-(beta-[3-(4-methoxy-phenyl) propoxy]-4-methoxyphenethyl)-1H-imidazole hydrochloride) is a general TRPC channel antagonist commonly used to characterize the potential functions of TRPC channels in cardiovascular system. Recent reports sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f8fc4a4bf38fd9c694f9c21aeb16083
https://pubmed.ncbi.nlm.nih.gov/25017106
https://pubmed.ncbi.nlm.nih.gov/25017106
Publikováno v:
Journal of Cellular Physiology.
Transient receptor potential melastatin-7 (TRPM7) channels are involved in many cellular physiological and pathological processes. The present study was designed to investigate the expression of TRPM7 channels and the potential role in regulating cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40fbe70eda63aea90486cc810d881da
https://doi.org/10.1002/jcp.24417
https://doi.org/10.1002/jcp.24417
Publikováno v:
European journal of pharmacology. 713(1-3)
Pentamethylquercetin (PMQ) has been shown to possess glucose-lowering properties, but its effect on renal fibrosis in diabetes is still unclear. This study was designed to investigate the effect of PMQ on renal fibrosis and the underlying mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78002ea90e9c0c7ea799d4312ef4c7bb
https://pubmed.ncbi.nlm.nih.gov/23665496
https://pubmed.ncbi.nlm.nih.gov/23665496
Autor:
Xiao-Hui Xu, Gui-Rong Li, Man-Wen Jin, Kui-Hao Chen, Zheng Liu, Yan Hu, Ji-Zhong Shen, Zhendong Jin, Xin-Ling Du, Yi Liu, Xin Xin
Publikováno v:
Biochemical pharmacology. 84(4)
The natural flavones and polymethylflavone have been reported to have cardiovascular protective effects. In the present study, we determined whether quecertin, apigenin and their methylated compounds (3,7,3',4'-tetramethylquecertin, 3,5,7,3',4'-penta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4fe1c3faf406a7096fa9bc686e7396
https://pubmed.ncbi.nlm.nih.gov/22583923
https://pubmed.ncbi.nlm.nih.gov/22583923
Autor:
Gui-Rong Li, Yan-Hui Zhang, Kui-Hao Chen, Man-Wen Jin, Xiao-Hui Xu, Xi-Yong Yu, Yi Liu, Chun-Yu Deng, Hai-Ying Sun, Wei Wu
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51550 (2012)
PLoS ONE
PLoS ONE
Allitridi (diallyl trisulfide) is an active compound (volatile oil) from garlic. The previous studies reported that allitridi had anti-arrhythmic effect. The potential ionic mechanisms are, however, not understood. The present study was designed to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7265ac169f8ae04495fce0e1318db2f
http://europepmc.org/articles/PMC3522701?pdf=render
http://europepmc.org/articles/PMC3522701?pdf=render