Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Kui Chan"'
Autor:
Linda Li-Dan Zhong, Yi-Ping Wong, Chor-Yin Leung, Bo Peng, Zhi-Xiu Lin, Vivian Chi-Woon Wong Taam, Yi Luo, Hai-Yong Chen, Chao-Dong Chao, Chor-Fung Wong, Freddie Shung-Chi Tam, Kui Chan, Kwan-Yiu Lee, Lai-Fun Ho, Alan Yat-Lun Wong, Chi-Fung Choy, Bacon Fung-Leung Ng, Rowena How-Wan Wong, Yi-Bin Feng, Ching Liong, Zhao-Xiang Bian, COVID-19 CM Research Working Group
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-24 (2022)
Abstract Objectives This study aimed to evaluate the effects of Chinese Medicine (CM) on the health condition of the post-COVID-19 patients, particularly with the CM Syndrome diagnosis and Body Constitutions (BC), as well as related clinical characte
Externí odkaz:
https://doaj.org/article/b8f5e610d5b74297a02d4274dddd77e9
Autor:
Linda Li-Dan Zhong, Yi-Ping Wong, Chor-Yin Leung, Bo Peng, Zhi-Xiu Lin, Vivian Chi-Woon Wong Taam, Yi Luo, Hai-Yong Chen, Chao-Dong Chao, Chor-Fung Wong, Freddie Shung-Chi Tam, Kui Chan, Kwan-Yiu Lee, Lai-Fun Ho, Alan Yat-Lun Wong, Chi-Fung Choy, Bacon Fung-Leung Ng, Rowena How-Wan Wong, Yi-Bin Feng, Ching Liong, Zhao-Xiang Bian, COVID-19 CM Research Working Group
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/61e5d84d93ac47b68501ff60f1fd3ac2
Autor:
Paige L. Snider, Elizabeth A. Sierra Potchanant, Zejin Sun, Donna M. Edwards, Ka-Kui Chan, Catalina Matias, Junya Awata, Aditya Sheth, P. Melanie Pride, R. Mark Payne, Michael Rubart, Jeffrey J. Brault, Michael T. Chin, Grzegorz Nalepa, Simon J. Conway
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8201 (2024)
Cardiomyopathy is the predominant defect in Barth syndrome (BTHS) and is caused by a mutation of the X-linked Tafazzin (TAZ) gene, which encodes an enzyme responsible for remodeling mitochondrial cardiolipin. Despite the known importance of mitochond
Externí odkaz:
https://doaj.org/article/cb3ba0ddacf3416ab3d640e28074c424
Autor:
Ka‐Kui Chan, Zahi Abdul‐Sater, Aditya Sheth, Dana K. Mitchell, Richa Sharma, Donna M. Edwards, Ying He, Grzegorz Nalepa, Steven D. Rhodes, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Publikováno v:
Molecular Oncology, Vol 16, Iss 4, Pp 860-884 (2022)
The Fanconi anemia (FA) pathway safeguards genomic stability through cell cycle regulation and DNA damage repair. The canonical tumor suppressive role of FA proteins in the repair of DNA damage during interphase is well established, but their functio
Externí odkaz:
https://doaj.org/article/af81c065551f42e1919675d6c2a442a5
Autor:
Donna M. Edwards, Dana K. Mitchell, Zahi Abdul-Sater, Ka-Kui Chan, Zejin Sun, Aditya Sheth, Ying He, Li Jiang, Jin Yuan, Richa Sharma, Magdalena Czader, Pei-Ju Chin, Yie Liu, Guillermo de Cárcer, Grzegorz Nalepa, Hal E. Broxmeyer, D. Wade Clapp, Elizabeth A. Sierra Potchanant
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Fanconi anemia (FA) is a disease of genomic instability and cancer. In addition to DNA damage repair, FA pathway proteins are now known to be critical for maintaining faithful chromosome segregation during mitosis. While impaired DNA damage repair ha
Externí odkaz:
https://doaj.org/article/3f11e067632b4f1cb8c3aaa365e91a9e
Overexpression of iASPP is required for autophagy in response to oxidative stress in choriocarcinoma
Autor:
Ka-Kui Chan, Esther Shuk-Ying Wong, Ivy Tsz-Lo Wong, Claire Ling-Yang Cheung, Oscar Gee-Wan Wong, Hextan Yuen-Sheung Ngan, Annie Nga-Yin Cheung
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background Gestational trophoblastic disease (GTD) is a heterogeneous group of diseases developed from trophoblasts. ASPP (Ankyrin-repeat, SH3-domain and proline-rich region containing protein) family proteins, ASPP1 and ASPP2, have been rep
Externí odkaz:
https://doaj.org/article/28836fccf0784da5b4b8429f486aa515
Autor:
Mohamed El-Tanani, Philip S. Rudland, Patrick G. Johnston, Dean A. Fennell, Pasi Janne, Ken O'Byrne, Osama Sharaf Eldin, Angela Platt-Higgins, James T. Murray, Claire Grills, Ka-Kui Chan, Hiu-Fung Yuen
Purpose: Cancer cells have been shown to be more susceptible to Ran knockdown than normal cells. We now investigate whether Ran is a potential therapeutic target of cancers with frequently found mutations that lead to higher Ras/MEK/ERK [mitogen-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70067d5af7d41e68e697ef0eda2aca32
https://doi.org/10.1158/1078-0432.c.6520403
https://doi.org/10.1158/1078-0432.c.6520403
Autor:
Mohamed El-Tanani, Philip S. Rudland, Patrick G. Johnston, Dean A. Fennell, Pasi Janne, Ken O'Byrne, Osama Sharaf Eldin, Angela Platt-Higgins, James T. Murray, Claire Grills, Ka-Kui Chan, Hiu-Fung Yuen
PDF file - 3.6K, Cancer cells with K-Ras activation mutation (HCT116/Hkh-2 isogenic pair) are more susceptible to Ran silencing-induced apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d29ff835d261255b4ca4e840b09a77
https://doi.org/10.1158/1078-0432.22445180.v1
https://doi.org/10.1158/1078-0432.22445180.v1
Autor:
Mohamed El-Tanani, Philip S. Rudland, Patrick G. Johnston, Dean A. Fennell, Pasi Janne, Ken O'Byrne, Osama Sharaf Eldin, Angela Platt-Higgins, James T. Murray, Claire Grills, Ka-Kui Chan, Hiu-Fung Yuen
PDF file - 144K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b106164f2577ebe341c7dbcec77b59b
https://doi.org/10.1158/1078-0432.22445168.v1
https://doi.org/10.1158/1078-0432.22445168.v1
Autor:
Mohamed El-Tanani, Philip S. Rudland, Patrick G. Johnston, Dean A. Fennell, Pasi Janne, Ken O'Byrne, Osama Sharaf Eldin, Angela Platt-Higgins, James T. Murray, Claire Grills, Ka-Kui Chan, Hiu-Fung Yuen
PDF file - 1.6MB, Percentage of sub-G1 phase apoptotic MCF10a and MDA MB231 cells grown in serum-containing medium after Ran silencing. (A-B) Cells were infected with shRan1 and shRan2. Medium was changed to serum-free medium (DMEM) 24hr post-infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d1782c7f6e5efb7ea82119caf5be40
https://doi.org/10.1158/1078-0432.22445192.v1
https://doi.org/10.1158/1078-0432.22445192.v1