Immunometabolic cues recompose and reprogram the microenvironment around implanted biomaterials.

Autor: Maduka CV; Comparative Medicine and Integrative Biology, Michigan State University, East Lansing, MI, USA. madukachima@gmail.com.; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA. madukachima@gmail.com.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA. madukachima@gmail.com.; BioFrontiers Institute, University of Colorado, Boulder, CO, USA. madukachima@gmail.com., Schmitter-Sánchez AD; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.; Cell and Molecular Biology Program, College of Natural Science, Michigan State University, East Lansing, MI, USA., Makela AV; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Ural E; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Stivers KB; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pope H; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Kuhnert MM; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Habeeb OM; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Tundo A; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA., Alhaj M; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, USA., Kiselev A; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.; Department of Medicine, College of Human Medicine, Michigan State University, East Lansing, MI, USA.; Department of Pharmacology and Toxicology, College of Human Medicine, Michigan State University, East Lansing, MI, USA., Chen S; School of Packaging, Michigan State University, East Lansing, MI, USA., Donneys A; Department of Orthopedic Surgery, University of Michigan Medical School, Ann Arbor, MI, USA., Winton WP; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Stauff J; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Scott PJH; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Olive AJ; Department of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA.; College of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA., Hankenson KD; Department of Orthopedic Surgery, University of Michigan Medical School, Ann Arbor, MI, USA., Narayan R; Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI, USA., Park S; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA.; Department of Medicine, College of Human Medicine, Michigan State University, East Lansing, MI, USA.; Department of Pharmacology and Toxicology, College of Human Medicine, Michigan State University, East Lansing, MI, USA., Elisseeff JH; Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Contag CH; Department of Biomedical Engineering, Michigan State University, East Lansing, MI, USA. contagch@msu.edu.; Institute for Quantitative Health Science and Engineering, Michigan State University, East Lansing, MI, USA. contagch@msu.edu.; Department of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA. contagch@msu.edu.

Publikováno v: Nature biomedical engineering [Nat Biomed Eng] 2024 Oct; Vol. 8 (10), pp. 1308-1321. Date of Electronic Publication: 2024 Oct 04.

A tension offloading patch mitigates dermal fibrosis induced by pro-fibrotic skin injections.

Autor: Talbott HE; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, 94305, USA., Griffin MF; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Mascharak S; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, 94305, USA., Parker JBL; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, 94305, USA., Kuhnert MM; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Guo JL; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Diaz Deleon NM; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Lavin C; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Abbas D; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Guardino N; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Morgan A; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Valencia C; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Cotterell A; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA., Longaker MT; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California, 94305, USA., Wan DC; Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine; Stanford, California, 94305, USA.

Publikováno v: Research square [Res Sq] 2024 Mar 01. Date of Electronic Publication: 2024 Mar 01.

Glycolytic reprogramming underlies immune cell activation by polyethylene wear particles.

Autor: Maduka CV; Comparative Medicine & Integrative Biology, Michigan State University, East Lansing, MI 48824, USA; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI 48824, USA., Habeeb OM; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI 48824, USA., Kuhnert MM; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI 48824, USA., Hakun M; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI 48824, USA., Goodman SB; Department of Orthopedic Surgery, Stanford University, CA 94063, USA; Department of Bioengineering, Stanford University, CA 94305, USA., Contag CH; Department of Biomedical Engineering, Michigan State University, East Lansing, MI 48824, USA; Institute for Quantitative Health Science & Engineering, Michigan State University, East Lansing, MI 48824, USA; Department of Microbiology & Molecular Genetics, Michigan State University, East Lansing, MI 48864, USA. Electronic address: contagch@msu.edu.

Publikováno v: Biomaterials advances [Biomater Adv] 2023 Sep; Vol. 152, pp. 213495. Date of Electronic Publication: 2023 Jun 03.