An electrically tight in vitro blood-brain barrier model displays net brain-to-blood efflux of substrates for the ABC transporters, P-gp, Bcrp and Mrp-1.

Autor: Helms HC; Department of Pharmacy, The Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, 2100, Copenhagen, Denmark., Hersom M, Kuhlmann LB, Badolo L, Nielsen CU, Brodin B

Publikováno v: The AAPS journal [AAPS J] 2014 Sep; Vol. 16 (5), pp. 1046-55. Date of Electronic Publication: 2014 Jun 17.