Aerobic capacity and exercise mediate protection against hepatic steatosis via enhanced bile acid metabolism.

Autor: Kugler BA; Departments of Cell Biology and Physiology.; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute., Maurer A; Departments of Cell Biology and Physiology., Fu X; Center for Human Nutrition and Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Franczak E; Departments of Cell Biology and Physiology.; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute., Ernst N; Departments of Cell Biology and Physiology., Schwartze K; Departments of Cell Biology and Physiology., Allen J; Departments of Cell Biology and Physiology., Li T; Department of Biochemistry and Physiology, and Harold Hamm Diabetes Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA., Crawford PA; Division of Molecular Medicine, Department of Medicine, and Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN., Koch LG; Dept of Physiology and Pharmacology, The University of Toledo, Toledo, OH, USA., Britton SL; Dept of Anesthesiology, University of Michigan, Ann Arbor, MI, USA., Burgess SC; Center for Human Nutrition and Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX, USA., Thyfault JP; Departments of Cell Biology and Physiology.; Internal Medicine, Division of Endocrinology and Clinical Pharmacology and KU Diabetes Institute.; Kansas Center for Metabolism and Obesity Research, Kansas Medical Center, Kansas City, KS, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 24. Date of Electronic Publication: 2024 Oct 24.

Divergence in aerobic capacity and energy expenditure influence metabolic tissue mitochondrial protein synthesis rates in aged rats.

Autor: Franczak E; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA.; Kansas City Veterans Affairs Medical Center, Kansas City, MO, 64128, USA., Maurer A; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA., Drummond VC; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA., Kugler BA; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA.; Kansas Center for Metabolism and Obesity Research, Kansas City, MO, 64128, USA.; KU Diabetes Institute and Department of Internal Medicine-Division of Endocrinology and Metabolism, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Hemenway Life Sciences Innovation Center, Mailstop 3043, Kansas City, KS, 66160, USA., Wells E; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA., Wenger M; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA.; Kansas Center for Metabolism and Obesity Research, Kansas City, MO, 64128, USA.; KU Diabetes Institute and Department of Internal Medicine-Division of Endocrinology and Metabolism, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Hemenway Life Sciences Innovation Center, Mailstop 3043, Kansas City, KS, 66160, USA., Peelor FF 3rd; Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA., Crosswhite A; Oklahoma Medical Research Foundation, Oklahoma City, OK, 73104, USA., McCoin CS; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA.; Kansas City Veterans Affairs Medical Center, Kansas City, MO, 64128, USA.; Kansas Center for Metabolism and Obesity Research, Kansas City, MO, 64128, USA.; KU Diabetes Institute and Department of Internal Medicine-Division of Endocrinology and Metabolism, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Hemenway Life Sciences Innovation Center, Mailstop 3043, Kansas City, KS, 66160, USA., Koch LG; Department of Physiology and Pharmacology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, 43606, USA., Britton SL; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, 48109, USA., Miller BF; KU Diabetes Institute and Department of Internal Medicine-Division of Endocrinology and Metabolism, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Hemenway Life Sciences Innovation Center, Mailstop 3043, Kansas City, KS, 66160, USA., Thyfault JP; Department of Cell Biology and Physiology, Medical Center, The University of Kansas, Kansas City, KS, 66160, USA. jthyfault@kumc.edu.; Kansas City Veterans Affairs Medical Center, Kansas City, MO, 64128, USA. jthyfault@kumc.edu.; Kansas Center for Metabolism and Obesity Research, Kansas City, MO, 64128, USA. jthyfault@kumc.edu.; KU Diabetes Institute and Department of Internal Medicine-Division of Endocrinology and Metabolism, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Hemenway Life Sciences Innovation Center, Mailstop 3043, Kansas City, KS, 66160, USA. jthyfault@kumc.edu.

Publikováno v: GeroScience [Geroscience] 2024 Apr; Vol. 46 (2), pp. 2207-2222. Date of Electronic Publication: 2023 Oct 26.

Divergence in aerobic capacity influences hepatic and systemic metabolic adaptations to bile acid sequestrant and short-term high-fat/sucrose feeding in rats.

Autor: Kugler BA; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States., Cao X; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States., Wenger M; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States., Franczak E; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States., McCoin CS; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States., Von Schulze A; Stowers Research Institute, Kansas City, Missouri, United States., Morris EM; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States., Thyfault JP; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, Kansas City, Missouri, United States.; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri, United States.; Department of Internal Medicine, Division of Endocrinology and Metabolism, KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States.

Publikováno v: American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2023 Dec 01; Vol. 325 (6), pp. R712-R724. Date of Electronic Publication: 2023 Oct 09.

Sexually dimorphic hepatic mitochondrial adaptations to exercise: a mini-review.

Autor: Kugler BA; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, The University of Kansas Medical Center, Kansas City, Kansas, United States., Thyfault JP; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri, United States.; Division of Endocrinology and Metabolism, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States., McCoin CS; Department of Cell Biology and Physiology, The University of Kansas Medical Center, Kansas City, Kansas, United States.; KU Diabetes Institute, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Kansas Center for Metabolism and Obesity Research, The University of Kansas Medical Center, Kansas City, Kansas, United States.; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri, United States.; Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, United States.

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985) [J Appl Physiol (1985)] 2023 Mar 01; Vol. 134 (3), pp. 685-691. Date of Electronic Publication: 2023 Jan 26.

Pharmacological inhibition of dynamin-related protein 1 attenuates skeletal muscle insulin resistance in obesity.

Autor: Kugler BA; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA., Deng W; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA.; School of Sports Medicine and Health, Chengdu Sport Institute, Chengdu, China., Duguay AL; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA., Garcia JP; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA., Anderson MC; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA., Nguyen PD; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA., Houmard JA; Department of Kinesiology, East Carolina University, Greenville, NC, USA.; Human Performance Laboratory, East Carolina University, Greenville, NC, USA., Zou K; Department of Exercise and Health Sciences, College of Nursing and Health Sciences, University of Massachusetts Boston, Boston, MA, USA.

Publikováno v: Physiological reports [Physiol Rep] 2021 Apr; Vol. 9 (7), pp. e14808.