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Akademický článek

Real-world experience of cabozantinib in Asian patients with advanced renal cell carcinoma following treatment with VEGFR tyrosine kinase inhibitors and/or immune checkpoint inhibitors

Autor: Darren MC Poon, Kuen Chan, Angus Kwong-Chuen Leung, Brian Ng, Foon-Yiu Cheung, Steven Wai-Kwan Siu, Hong Kong Society of Uro-Oncology

Publikováno v: Drugs in Context, Vol 12, Pp 1-9 (2023)

Background: There is a lack of real-world data on the use of cabozantinib in Asian patients with metastatic renal cell carcinoma. Methods: We conducted a retrospective study to investigate the toxicity and efficacy of cabozantinib in this patient

Externí odkaz: https://doaj.org/article/2d389a82eb894cf187dc51ecdc1b4fc8

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Akademický článek

Addressing the risk and management of cardiometabolic complications in prostate cancer patients on androgen deprivation therapy and androgen receptor axis-targeted therapy: consensus statements from the Hong Kong Urological Association and the Hong Kong Society of Uro-Oncology

Autor: Darren M. C. Poon, Guang-Ming Tan, Kuen Chan, Marco T. Y. Chan, Tim-Wai Chan, Raymond W. M. Kan, Martin H. C. Lam, Clarence L. H. Leung, Kenneth C. W. Wong, Kevin K. H. Kam, Chi-Fai Ng, Peter K. F. Chiu

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

BackgroundAndrogen deprivation therapy (ADT) is the foundational treatment for metastatic prostate cancer (PCa). Androgen receptor (AR) axis-targeted therapies are a new standard of care for advanced PCa. Although these agents have significantly impr

Externí odkaz: https://doaj.org/article/647ec4050db24cd28b254ed2c3cf2112

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Akademický článek

Differences in clinical outcome between docetaxel and abiraterone acetate as the first-line treatment in chemo-naïve metastatic castration-resistant prostate cancer patients with or without the ineligible clinical factors of the COU-AA-302 study

Autor: Darren M.C. Poon, Kuen Chan, Siu H. Lee, Tim W. Chan, Henry Sze, Eric K.C. Lee, Daisy Lam, Michelle F.T. Chan

Publikováno v: Prostate International, Vol 6, Iss 1, Pp 24-30 (2018)

Background: This study aimed to compare the efficacy of abiraterone acetate (AA) versus docetaxel (T) as first-line treatment in chemo-naïve metastatic castration-resistant prostate cancer (mCRPC) patients with or without the ineligible factors of t

Externí odkaz: https://doaj.org/article/edf841c8b6844c12b76d3bd3b64b9b71

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Akademický článek

Importance of cycles of chemotherapy and postdocetaxel novel therapies in metastatic castration-resistant prostate cancer

Autor: Darren M.C. Poon, Joyce Ng, Kuen Chan

Publikováno v: Prostate International, Vol 3, Iss 2, Pp 51-55 (2015)

Purpose: With the emergence of various novel therapies including new generation taxane and androgen-targeted therapies, the optimal sequence of systemic treatment in metastatic castration-resistant prostate cancer (mCRPC) patients remains to be defin

Externí odkaz: https://doaj.org/article/9cd3278a107c4373a4ea71e10d08bfb9

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