Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Kuei-sen Hsu"'
Autor:
Hao-Wei Lee, Szu-Jung Chen, Kuen-Jer Tsai, Kuei-Sen Hsu, Yi-Fan Chen, Chih-Hua Chang, Hsiao-Han Lin, Wen-Yun Hsueh, Hsing-Pang Hsieh, Yueh-Feng Lee, Huai-Chueh Chiang, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-23 (2024)
Abstract Background Cathepsin S (CTSS) is a cysteine protease that played diverse roles in immunity, tumor metastasis, aging and other pathological alterations. At the cellular level, increased CTSS levels have been associated with the secretion of p
Externí odkaz:
https://doaj.org/article/cb18c5ca1d994f6798eb6006543573e6
Autor:
Han-Ying Wang, Hiroshi Takagi, Patrick N. Stoney, Anai Echeverria, Bernd Kuhn, Kuei-Sen Hsu, Tomoyuki Takahashi
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109515- (2024)
Summary: Transient anoxia causes amnesia and neuronal death. This is attributed to enhanced glutamate release and modeled as anoxia-induced long-term potentiation (aLTP). aLTP is mediated by glutamate receptors and nitric oxide (·NO) and occludes st
Externí odkaz:
https://doaj.org/article/1071ce67fe7c4090a1186b026dea20dd
Publikováno v:
Neurobiology of Disease, Vol 187, Iss , Pp 106311- (2023)
Hippocampal oxytocin receptor (OXTR) signaling is crucial for discrimination of social stimuli to guide social recognition, but circuit mechanisms and cell types involved remain incompletely understood. Here, we report a role for OXTR-expressing hila
Externí odkaz:
https://doaj.org/article/f346f313adc94710985b0f5878f9c145
Publikováno v:
JCI Insight, Vol 8, Iss 12 (2023)
Inflammatory bowel disease (IBD) is a relapsing-remitting disorder characterized by chronic inflammation of the gastrointestinal (GI) tract. Anxiety symptoms are commonly observed in patients with IBD, but the mechanistic link between IBD and anxiety
Externí odkaz:
https://doaj.org/article/a2e374c3fcab45329d35e2ac37088f76
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-20 (2022)
Abstract Background Social recognition memory (SRM) is the ability to distinguish familiar from novel conspecifics and is crucial for survival and reproductive success across social species. We previously reported that oxytocin (OXT) receptor (OXTR)
Externí odkaz:
https://doaj.org/article/f029d8a5ddd04889a000b6ca7c37d940
Autor:
Yi-Ting Fang, Tsung-Lin Lee, Yi-Hsien Tu, Sheng-Hsiang Lin, Miao-Er Chien, Chin-Wei Huang, Kuei-Sen Hsu, Yi-Jen Wu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Super-refractory status epilepticus (SRSE) is a critical condition in which seizures persist despite anesthetic use for 24 h or longer. High mortality has been reported in patients with SRSE, but the cause of death remains unclear. We invest
Externí odkaz:
https://doaj.org/article/f8f10c0c21bf4c3b9cf59522d0b303fc
Autor:
Wan-Yu Huang, Yen-Ling Lai, Ko-Hung Liu, Shankung Lin, Hsuan-Ying Chen, Chih-Hung Liang, Hung-Ming Wu, Kuei-Sen Hsu
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Systemic inflammation is a potent contributor to increased seizure susceptibility. However, information regarding the effects of systemic inflammation on cerebral vascular integrity that influence neuron excitability is scarce. Ne
Externí odkaz:
https://doaj.org/article/dfb6936973e349f3acd45a3db7f0332c
Publikováno v:
Brain Stimulation, Vol 16, Iss 1, Pp 303- (2023)
Externí odkaz:
https://doaj.org/article/79f6d95587ae40deb0a9a6ee1b23c5fc
Publikováno v:
Brain Stimulation, Vol 14, Iss 4, Pp 771-779 (2021)
Background: Transcranial direct current stimulation (tDCS) provides a noninvasive polarity-specific constant current to treat epilepsy, through a mechanism possibly involving excitability modulation and neural oscillation. Objective: To determine whe
Externí odkaz:
https://doaj.org/article/18a03c3af6bf4caabae059344a252a56
Autor:
Nam-Shik Kim, Zhexing Wen, Jing Liu, Ying Zhou, Ziyuan Guo, Chongchong Xu, Yu-Ting Lin, Ki-Jun Yoon, Junhyun Park, Michelle Cho, Minji Kim, Xinyuan Wang, Huimei Yu, Srilatha Salamuru, Kimberly M. Christian, Kuei-sen Hsu, Menghang Xia, Weidong Li, Christopher A. Ross, Russell L. Margolis, Xin-Yun Lu, Hongjun Song, Guo-li Ming
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Previous work has shown in iPSC derived neurons that synaptic impairments are associated with a 4bp DISC1 deletion. Here the authors demonstrate a role for the PDE4 signalling pathway in these synaptic impairments.
Externí odkaz:
https://doaj.org/article/a1c93081300b4869a2a2b16a518720f6