Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation.

Autor: Chowdhury NU; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Cephus JY; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., Henriquez Pilier E; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Wolf MM; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Madden MZ; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Kuehnle SN; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., McKernan KE; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Jennings EQ; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, United States of America., Arner EN; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, United States of America., Heintzman DR; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Chi C; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Sugiura A; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Stier MT; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, United States of America., Voss K; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Ye X; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, United States of America., Scales KL; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., Krystofiak ES; Department of Cellular and Molecular Biology, Vanderbilt University Medical Center, Nashville, United States of America., Gandhi VD; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., Guzy RD; Department of Medicine, University of Wisconsin, Madison, United States of America., Cahill KN; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., Sperling AI; Department of Medicine, University of Virginia, Charlottesville, United States of America., Peebles RS Jr; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America., Rathmell JC; Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, United States of America., Newcomb DC; Department of Medicine, Vanderbilt University Medical Center, Nashville, United States of America.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2024 Oct 01. Date of Electronic Publication: 2024 Oct 01.

How early life respiratory viral infections impact airway epithelial development and may lead to asthma.

Autor: Berdnikovs, Sergejs, Newcomb, Dawn C., Hartert, Tina V.

Publikováno v: Frontiers in Pediatrics; 2024, p1-10, 10p