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Akademický článek

High-resolution epitope mapping of commercial antibodies to ANCA antigens by yeast surface display.

Autor: Poulton JS; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; UNC Kidney Center, Chapel Hill, North Carolina, USA. Electronic address: poultonj@email.unc.edu., Lamba S; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Free M; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; UNC Kidney Center, Chapel Hill, North Carolina, USA., Xi G; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; UNC Kidney Center, Chapel Hill, North Carolina, USA., McInnis E; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Williams G; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; Menten AI, San Francisco, California, USA., Thieker D; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Falk R; Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; UNC Kidney Center, Chapel Hill, North Carolina, USA.

Publikováno v: Journal of immunological methods [J Immunol Methods] 2024 May; Vol. 528, pp. 113654. Date of Electronic Publication: 2024 Mar 01.

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Akademický článek

Stabilizing proteins, simplified: A Rosetta-based webtool for predicting favorable mutations.

Autor: Thieker DF; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Maguire JB; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Leaver-Fay A; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA., Lyskov S; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland, USA., Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.; Lineburger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Publikováno v: Protein science : a publication of the Protein Society [Protein Sci] 2022 Oct; Vol. 31 (10), pp. e4428.

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Akademický článek

A conserved set of mutations for stabilizing soluble envelope protein dimers from dengue and Zika viruses to advance the development of subunit vaccines.

Autor: Phan TTN; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Hvasta MG; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Thiono DJ; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Tripathy A; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Nicely NI; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., de Silva AM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA. Electronic address: bkuhlman@email.unc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 Jul; Vol. 298 (7), pp. 102079. Date of Electronic Publication: 2022 May 26.

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Akademický článek

Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies.

Autor: Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Metz S; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA., Thiono D; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA., Payne AM; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Phan TTN; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Tian S; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA., Forsberg LJ; Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27514, USA., Maguire J; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Seim I; Curriculum in Bioinformatics and Computational Biology, University of North Carolina, Chapel Hill, NC 27514, USA.; Department of Biology, University of North Carolina, Chapel Hill, NC 27514, USA.; Department of Applied Physical Sciences, University of North Carolina, Chapel Hill, NC 27514, USA., Zhang S; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Tripathy A; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Harrison J; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA., Nicely NI; Department of Pharmacology, University of North Carolina, Chapel Hill, NC 27514, USA., Soman S; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., McCracken MK; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Gromowski GD; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Jarman RG; Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA., Premkumar L; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA., de Silva AM; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC 27514, USA., Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC 27514, USA.; Department of Biology, University of North Carolina, Chapel Hill, NC 27514, USA.

Publikováno v: Science advances [Sci Adv] 2021 Oct 15; Vol. 7 (42), pp. eabg4084. Date of Electronic Publication: 2021 Oct 15.

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Akademický článek

Dimerization of Dengue Virus E Subunits Impacts Antibody Function and Domain Focus.

Autor: Thomas A; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA., Thiono DJ; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA., Kudlacek ST; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, USA., Forsberg J; Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina, USA., Premkumar L; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA., Tian S; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA., Kuhlman B; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, North Carolina, USA., de Silva AM; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA., Metz SW; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina, USA swmetz@med.unc.edu.

Publikováno v: Journal of virology [J Virol] 2020 Aug 31; Vol. 94 (18). Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).

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