Macrophage-Derived Iron-Bound Lipocalin-2 Correlates with Renal Recovery Markers Following Sepsis-Induced Kidney Damage

Autor: Mertens, C., Kuchler, L., Sola, A., Guiteras, R., Grein, S., Brüne, B., Knethen, A. von, Jung, M.

Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 20
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 21, Iss 7527, p 7527 (2020)

During the course of sepsis in critically ill patients, kidney dysfunction and damage are among the first events of a complex scenario toward multi-organ failure and patient death. Acute kidney injury triggers the release of lipocalin-2 (Lcn-2), whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b9d0c3a95f5d1446d122ae2ae8b52843
http://europepmc.org/articles/PMC7589935

Maintaining hepatic PD-L1 expression improves sepsis survival in a murine polymicrobial sepsis model by tolerizing CTL

Autor: Knethen, A. von, Schäfer, A., Kuchler, L., Knape, T., Christen, U., Hintermann, E., Fisslthaler, B., Schröder, K., Brandes, R.P., Genz, B., Abshagen, K., Pützer, B.M., Sha, L.K., Weigert, A., Syed, S.N., Schulz, M., Shah, A.M., Ernst, A., Putyrski, M., Finkelmeier, F., Pesic, M., Greten, F., Hoghardt, M., Kempf, V.A.J., Gunne, S., Parnham, M.J., Brüne, B.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::f7016274ee761ef910a907b31264c10a
https://publica.fraunhofer.de/handle/publica/260284

PPARgamma as a putative stress marker in T cells following kidney transplantation

Autor: Aghajaanpour, R., Brenneis, M., Köhler, N., Knape, T., Büttner, S., Kuchler, L., Parnham, M.J., Bruene, B., Hauser, I.A., Knethen, A. von

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::8bebdf4d876c25c0d90e6aa4641200cd
https://publica.fraunhofer.de/handle/publica/252524

MTTB: A new pharmacological concept for sepsis

Autor: Knape, T., Flesch, D., Kuchler, L., Sha, L.K., Giegerich, A.K., Nova, N.V., Labocha, S., Ferreiros, N., Schmid, T., Wacker, M., Wurglics, M., Zsilavecz, S., Proschak, E., Brune, B., Parnham, M.J., Knethen, A. von

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::8bed0c25a85ed1f2e8881e611f235200
https://publica.fraunhofer.de/handle/publica/243017

SYNCRIP-dependent Nox2 mRNA destabilization impairs ROS formation in M2-polarized macrophages

Autor: Kuchler, L., Giegerich, A.K., Sha, L.K., Knape, T., Wong, M.S.K., Schröder, K., Brandes, R.P., Heide, H., Wittig, I., Brüne, B., Knethen, A. von

Aims: During sepsis, macrophages are alternatively activated toward an M2-like phenotype on contact with apoptotic cells (ACs) or their secretion products. Simultaneously, NADPH oxidase-dependent reactive oxygen species (ROS) formation is attenuated,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______610::b6aecf24b285cf1e047ae6421da3cecf
https://publica.fraunhofer.de/handle/publica/241485