Targeted Polymersome Delivery of a Stapled Peptide for Drugging the Tumor Protein p53:BCL-2-Family Axis in Diffuse Large B-Cell Lymphoma.

Autor: Schnorenberg MR; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States.; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States.; Medical Scientist Training Program, Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, United States., Hawley KM; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States., Thomas-Toth AT; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States., Watkins EA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States., Tian Y; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States.; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States., Ting JM; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States., Leak LB; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States., Kucera IM; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States.; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States., Raczy MM; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States., Kung AL; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, United States., Hubbell JA; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States., Tirrell MV; Pritzker School of Molecular Engineering, University of Chicago, Chicago, Illinois 60637, United States., LaBelle JL; Department of Pediatrics, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois 60637, United States.

Publikováno v: ACS nano [ACS Nano] 2023 Dec 12; Vol. 17 (23), pp. 23374-23390. Date of Electronic Publication: 2023 Sep 09.