Výsledky vyhledávání - "Kuang-Hui Sun"

Akademický článek

PDK1- and PDK2-mediated metabolic reprogramming contributes to the TGFβ1-promoted stem-like properties in head and neck cancer

Autor: Wan-Hsuan Sun, Yun-Hsuan Chen, Hou-Hsuan Lee, Yu-Wen Tang, Kuang-Hui Sun

Publikováno v: Cancer & Metabolism, Vol 10, Iss 1, Pp 1-16 (2022)

Abstract Background Resistance to chemotherapeutic drugs is a key factor for cancer recurrence and metastases in head and neck cancer (HNC). Cancer stem cells (CSCs) in tumors have self-renewal, differentiation, and higher drug resistance capabilitie

Externí odkaz: https://doaj.org/article/ff8c648047aa4e139d2f7b13650e6646

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Akademický článek

Chimeric 6‐methylsalicylic acid synthase with domains of acyl carrier protein and methyltransferase from Pseudallescheria boydii shows novel biosynthetic activity

Autor: Ji‐Long Liao, Ka‐Lai Pang, Guang‐Huan Sun, Tun‐Wen Pai, Pang‐Hung Hsu, Jyuan‐Siou Lin, Kuang‐Hui Sun, Chii‐Cheng Hsieh, Shye‐Jye Tang

Publikováno v: Microbial Biotechnology, Vol 12, Iss 5, Pp 920-931 (2019)

Summary Polyketides are important secondary metabolites, many of which exhibit potent pharmacological applications. Biosynthesis of polyketides is carried out by a single polyketide synthase (PKS) or multiple PKSs in successive elongations of enzyme�

Externí odkaz: https://doaj.org/article/da9098e3c04948bcb986b870eb945f63

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Akademický článek

Examination of Fas-Induced Apoptosis of Murine Thymocytes in Thymic Tissue Slices Reveals That Fas Is Dispensable for Negative Selection

Autor: Chang-Feng Chu, Hsing-Kai Feng, Kuang-Hui Sun, Chia-Lin Hsu, Ivan L. Dzhagalov

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 8 (2020)

The death receptor Fas can induce cell death through the extrinsic pathway of apoptosis in a variety of cells, including developing thymocytes. Although Fas-induced cell death has been researched and modeled extensively, most of the studies have been

Externí odkaz: https://doaj.org/article/da3b7c544b1a4a1d8833b9db48e1d442

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Akademický článek

The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation.

Autor: Mei-Jen Chuang, Sheng-Tang Wu, Shou-Hung Tang, Xiang-Me Lai, Hsiao-Chu Lai, Kai-Hsiang Hsu, Kuang-Hui Sun, Guang-Huan Sun, Sun-Yran Chang, Dah-Shyong Yu, Pei-Wen Hsiao, Shih-Ming Huang, Tai-Lung Cha

Publikováno v: PLoS ONE, Vol 8, Iss 9, p e73401 (2013)

Histone deacetylase inhibitors (HDACIs) have potent anti-cancer activity in a variety of cancer models. Understanding the molecular mechanisms involved in the therapeutic responsiveness of HDACI is needed before its clinical application. This study a

Externí odkaz: https://doaj.org/article/9096e7b26fb74e678d8a72e8ebaa38cb

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CXCR3 isoform A promotes head and neck cancer progression by enhancing stem‐like property and chemoresistance

Autor: Wan-Hsuan, Sun, Ta-Jung, Peng, Shye-Jye, Tang, Jo-Yu, Lin, Chia-Yi, Wang, Hsueh-Jou, Fang, Kuang-Hui, Sun

Publikováno v: Journal of Oral Pathology & Medicine. 51:791-800

The chemokine network orchestrates the cancer stem-like property and consequently participates in cancer progression. CXCR3 contributes cancer progressive property and immunomodulation in the tumor microenvironment. The two major isoforms of CXCR3 ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79613beb26dbea252e62805ee798a97
https://doi.org/10.1111/jop.13346

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