Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Kuang Yu. Jen"'
Autor:
Brendon Lutnick, David Manthey, Jan U. Becker, Brandon Ginley, Katharina Moos, Jonathan E. Zuckerman, Luis Rodrigues, Alexander J. Gallan, Laura Barisoni, Charles E. Alpers, Xiaoxin X. Wang, Komuraiah Myakala, Bryce A. Jones, Moshe Levi, Jeffrey B. Kopp, Teruhiko Yoshida, Jarcy Zee, Seung Seok Han, Sanjay Jain, Avi Z. Rosenberg, Kuang Yu. Jen, Pinaki Sarder, the Kidney Precision Medicine Project
Publikováno v:
Communications Medicine, Vol 2, Iss 1, Pp 1-15 (2022)
Lutnick et al. develop a cloud-based deep learning tool for whole slide image segmentation. The authors provide several examples of its application in renal pathology, for segmenting glomeruli, interstitial fibrosis and other features of interest.
Externí odkaz:
https://doaj.org/article/55a83f05e2a54ed1a808a7fafb19b7b9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Managing patients with kidney allografts largely depends on biopsy diagnosis which is based on semiquantitative assessments of rejection features and extent of acute and chronic changes within the renal parenchyma. Current methods lack repro
Externí odkaz:
https://doaj.org/article/2dcf470ed769426f9fae424a477885ee
Publikováno v:
PeerJ Computer Science, Vol 10, p e1888 (2024)
Background Pathology reports contain key information about the patient’s diagnosis as well as important gross and microscopic findings. These information-rich clinical reports offer an invaluable resource for clinical studies, but data extraction a
Externí odkaz:
https://doaj.org/article/dab2e45b790f4775a855a62502af880a
Publikováno v:
Case Reports in Nephrology, Vol 2024 (2024)
Kidney complications can occur due to infective endocarditis, one of which is glomerulonephritis. Most often, an immune complex or complement-mediated glomerulonephritis is seen on kidney biopsy. In a minor subset of cases, pauci-immune glomeruloneph
Externí odkaz:
https://doaj.org/article/a068af011c3844c09317c8dd07333368
Autor:
Nicholas Lucarelli, Donghwan Yun, Dohyun Han, Brandon Ginley, Kyung Chul Moon, Avi Z. Rosenberg, John E. Tomaszewski, Jarcy Zee, Kuang-Yu Jen, Seung Seok Han, Pinaki Sarder
Publikováno v:
medRxiv
BackgroundThe heterogeneous phenotype of diabetic nephropathy (DN) from type 2 diabetes complicates appropriate treatment approaches and outcome prediction. Kidney histology helps diagnose DN and predict its outcomes, and an artificial intelligence (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dabb9eef307f09ea94745d2a3cbf17
https://doi.org/10.1101/2023.04.28.23289272
https://doi.org/10.1101/2023.04.28.23289272
Autor:
Ayano Kondo, Monee McGrady, Dhiraj Nallapothula, Hira Ali, Alexandro E. Trevino, Amy Lam, Ryan Preska, H. Blaize D’Angio, Zhenqin Wu, Lauren Lopez, Harshanna Kaur Badhesha, Chenoa Rochel Vargas, Achyuta Ramesh, Nasim Wiegley, Seung Seok Han, Marc Dall’Era, Kuang-Yu Jen, Aaron T. Mayer, Maryam Afkarian
Aims/HypothesisDiabetic kidney disease (DKD) remains a significant cause of morbidity and mortality in people with diabetes. Though animal models have taught us much about the molecular mechanisms of DKD, translating these findings to human disease r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7cbc886ec46791369929a21d929de6b
https://doi.org/10.1101/2023.04.12.534028
https://doi.org/10.1101/2023.04.12.534028
Autor:
Jian-Hua Mao, Allan Balmain, Guangwei Wei, Jesus Perez-Losada, Kuang-Yu Jen, Reyno DelRosario, Hio Chung Kang, Yurong Huang, Yueyong Liu, William A. Stock, Jing Lu, Di Wu, Il-Jin Kim, Yong-Won Kwon
PDF file - 222K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409d249f5270f369a43e725ff50207e6
https://doi.org/10.1158/1541-7786.22516908.v1
https://doi.org/10.1158/1541-7786.22516908.v1
Autor:
Jian-Hua Mao, Allan Balmain, Guangwei Wei, Jesus Perez-Losada, Kuang-Yu Jen, Reyno DelRosario, Hio Chung Kang, Yurong Huang, Yueyong Liu, William A. Stock, Jing Lu, Di Wu, Il-Jin Kim, Yong-Won Kwon
The Aurora-A kinase gene is frequently amplified and/or overexpressed in a variety of human cancers, leading to major efforts to develop therapeutic agents targeting this pathway. Here, we show that Aurora-A is targeted for ubiquitination and subsequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4683175472a6d135526e2086cb935038
https://doi.org/10.1158/1541-7786.c.6541539
https://doi.org/10.1158/1541-7786.c.6541539
Autor:
Eric A. Collisson, Matthew Meyerson, Angela Brooks, Byron Hann, Youngho Seo, Kuang-Yu Jen, Sergio Wong, Alice H. Berger, Peter Choi, Wei Wu, John Greer, Nir Peled, Xinyuan Lu
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d79f3379b9df801161909c501e6ee93
https://doi.org/10.1158/0008-5472.22415409
https://doi.org/10.1158/0008-5472.22415409
Autor:
Eric A. Collisson, Matthew Meyerson, Angela Brooks, Byron Hann, Youngho Seo, Kuang-Yu Jen, Sergio Wong, Alice H. Berger, Peter Choi, Wei Wu, John Greer, Nir Peled, Xinyuan Lu
Targeting somatically activated oncogenes has revolutionized the treatment of non–small cell lung cancer (NSCLC). Mutations in the gene mesenchymal–epithelial transition (MET) near the exon 14 splice sites are recurrent in lung adenocarcinoma and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06b31515f726432a062b55e5ec700e01
https://doi.org/10.1158/0008-5472.c.6509274.v1
https://doi.org/10.1158/0008-5472.c.6509274.v1