Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kuan-Minn Cha"'
Autor:
Christopher H Scott, Kuan-Minn Cha, Jason Ngai, Changtao Jiang, Kim Cheng, Rebecca A Stokes, Kenneth W K Ho, Jacob George, Frank J Gonzalez, Jenny E Gunton
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186543 (2017)
Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) and its partners hypoxia-inducible factors (HIF)-1α and HIF-2α are candidate factors for the well-known link between the liver, metabolic dysfunction and elevation in circulating lipids and gluc
Externí odkaz:
https://doaj.org/article/b07a777ca221483bb4f3576a2575da81
Autor:
Sevasti Zervou, Debra J. McAndrew, Hannah J. Whittington, Hannah A. Lake, Kyung Chan Park, Kuan Minn Cha, Philip J. Ostrowski, Thomas R. Eykyn, Jürgen E. Schneider, Stefan Neubauer, Craig A. Lygate
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
AimsAdenylate kinase 1 (AK1) catalyses the reaction 2ADP ↔ ATP + AMP, extracting extra energy under metabolic stress and promoting energetic homeostasis. We hypothesised that increased AK1 activity would have negligible effects at rest, but protect
Externí odkaz:
https://doaj.org/article/4987ce7164ec4b948b413bb6efbed548
Autor:
Christopher Scott, Rebecca Stokes, Kuan Minn Cha, Andrew Clouston, Mohammed Eslam, Mayda Metwally, Michael M Swarbrick, Jacob George, Jenny E Gunton
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0225332 (2019)
BACKGROUND AND AIM:Non-alcoholic steatohepatitis (NASH) is predicted to become the most common cause of cirrhosis and liver failure. Risk factors include obesity, insulin resistance and diabetes. Macrophages and other myeloid cells play crucial roles
Externí odkaz:
https://doaj.org/article/f9a3743b22274f67b607c94eed3743ca
Autor:
Mayda Metwally, Jenny E. Gunton, Andrew D. Clouston, Jacob George, Mohammed Eslam, Kuan Minn Cha, Rebecca A. Stokes, Christopher Scott, Michael M. Swarbrick
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 12, p e0225332 (2019)
PLoS ONE, Vol 14, Iss 12, p e0225332 (2019)
Background and aim Non-alcoholic steatohepatitis (NASH) is predicted to become the most common cause of cirrhosis and liver failure. Risk factors include obesity, insulin resistance and diabetes. Macrophages and other myeloid cells play crucial roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2f78e5b920498790ccc6d1f611f649
https://doi.org/10.1371/journal.pone.0225332
https://doi.org/10.1371/journal.pone.0225332
Autor:
Kenneth W. K. Ho, Kuan-Minn Cha, Jacob George, Kim Cheng, Changtao Jiang, Christopher Scott, Rebecca A. Stokes, Jason Ngai, Frank J. Gonzalez, Jenny E. Gunton
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186543 (2017)
PLoS ONE
PLoS ONE
Background & aims Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) and its partners hypoxia-inducible factors (HIF)-1α and HIF-2α are candidate factors for the well-known link between the liver, metabolic dysfunction and elevation in circulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6902d3d6255f9b02f3ed8d5b1f00dd26
http://europepmc.org/articles/PMC5708799?pdf=render
http://europepmc.org/articles/PMC5708799?pdf=render
Autor:
Jenny E. Gunton, Nancy Mokbel, Rebecca S. Mason, Roderick J. Clifton-Bligh, Peter J. Houweling, Christian M. Girgis, Kuan Minn Cha, Myriam Abboud, David R. Fraser
Publikováno v:
Endocrinology
Vitamin D deficiency is associated with a range of muscle disorders, including myalgia, muscle weakness, and falls. In humans, polymorphisms of the vitamin D receptor (VDR) gene are associated with variations in muscle strength, and in mice, genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433b6893b12ae51f5470b324aa84e2d9
https://doi.org/10.1210/en.2014-1016
https://doi.org/10.1210/en.2014-1016
Autor:
Kuan Minn Cha, James Bonner, Danqing Min, Susan V. McLennan, Jenny E. Gunton, Rebecca A. Stokes, Kendle M. Maslowski, Frederic Sierro, Stacey N. Walters, Shane T. Grey, Christopher Scott, Stephen M. Twigg, Philip Boughton
Publikováno v:
American Journal of Physiology-Cell Physiology. 307:C349-C357
Aryl hydrocarbon receptor nuclear translocator (ARNT) is a transcription factor that binds to partners to mediate responses to environmental signals. To investigate its role in the innate immune system, floxed ARNT mice were bred with lysozyme M-Cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916960447245dbd60059ac7e70e7d7ee
https://doi.org/10.1152/ajpcell.00306.2013
https://doi.org/10.1152/ajpcell.00306.2013
Autor:
Mike Lin, Roderick J. Clifton-Bligh, Jenny E. Gunton, Peter J. Houweling, Nancy Mokbel, Christian M. Girgis, Kuan Minn Cha, Renuka Rao
Publikováno v:
Calcified tissue international. 97(6)
Vitamin D deficiency is associated with muscle weakness, pain, and atrophy. Serum vitamin D predicts muscle strength and age-related muscle changes. However, precise mechanisms by which vitamin D affects skeletal muscle are unclear. To address this q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fae0a0fd2d953e8b602e46b2582776c
https://pubmed.ncbi.nlm.nih.gov/26340892
https://pubmed.ncbi.nlm.nih.gov/26340892
Autor:
Mark McLean, Jenny E. Gunton, Ayesha Karunatillake, Sue Mei Lau, Kim Cheng, N. W. Cheung, Rebecca A. Stokes, Frank J. Gonzalez, Kuan Minn Cha
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77419 (2013)
PLoS ONE
PLoS ONE
Aims Insulin secretion increases in normal pregnancy to meet increasing demands. Inability to increase beta-cell function results in gestational diabetes mellitus (GDM). We have previously shown that the expression of the transcription factor ARNT (A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2c864851fc20c10d5cbcbe6adf759f
https://doi.org/10.1371/journal.pone.0077419
https://doi.org/10.1371/journal.pone.0077419
Autor:
Christian M. Girgis, Kuan Minn Cha, Benjamin So, Michael Tsang, Jennifer Chen, Peter J. Houweling, Aaron Schindeler, Rebecca Stokes, Michael M. Swarbrick, Frances J. Evesson, Sandra T. Cooper, Jenny E. Gunton
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 10, Iss 6, Pp 1228-1240 (2019)
Abstract Background It has long been recognized that vitamin D deficiency is associated with muscle weakness and falls. Vitamin D receptor (VDR) is present at very low levels in normal muscle. Whether vitamin D plays a direct role in muscle function
Externí odkaz:
https://doaj.org/article/e85a74adec2744dfa47b6bbcb41c8cf1