Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kuan-Boone Tan"'
Autor:
Peter Kilbride, Holly J. Woodward, Kuan Boone Tan, Nguyễn T.K. Thanh, K.M. Emily Chu, Shane Minogue, Mark G. Waugh
Publikováno v:
PeerJ, Vol 3, p e1351 (2015)
Cholesterol has important functions in the organization of membrane structure and this may be mediated via the formation of cholesterol-rich, liquid-ordered membrane microdomains often referred to as lipid rafts. Methyl-beta-cyclodextrin (cyclodextri
Externí odkaz:
https://doaj.org/article/66f6f6dd93da42388b914f4ae3c003d9
Publikováno v:
Nanomedicine. 9:1665-1679
Aim: The aim of this work was to develop a liposomal formulation to facilitate delivery of a synergistic safingol/C2-ceramide combination in the treatment of acute myeloid leukemia (AML). Materials & methods: Liposomes were prepared using the extrusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3656fe48c3aabb6af2b01707f47be451
https://doi.org/10.2217/nnm.13.123
https://doi.org/10.2217/nnm.13.123
Autor:
Anumita Chaudhury, Gigi N.C. Chiu, Kuan-Boone Tan, Bernice M.J. Tan, Ishaque M. Shaikh, Yuanjie Liu, Bee Jen Tan
Publikováno v:
Journal of Controlled Release. 172:852-861
Liposome co-encapsulation of synergistic anti-cancer drug combination is an emerging area that has demonstrated therapeutic benefit in clinical trials. Remote loading of two or more drugs into a single liposome constitutes a new challenge that calls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27fdb8492983aeac97fae2b3bb233f0d
https://doi.org/10.1016/j.jconrel.2013.10.025
https://doi.org/10.1016/j.jconrel.2013.10.025
Autor:
Mark G. Waugh, Holly J. Woodward, Nguyen T. K. Thanh, Shane Minogue, Peter Kilbride, K. M. Emily Chu, Kuan-Boone Tan
Publikováno v:
PeerJ, Vol 3, p e1351 (2015)
PeerJ
PeerJ
Cholesterol has important functions in the organization of membrane structure and this may be mediated via the formation of cholesterol-rich, liquid-ordered membrane microdomains often referred to as lipid rafts. Methyl-beta-cyclodextrin (cyclodextri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58435bb30c1836cc6ec5f15b6556f74f
https://peerj.com/articles/1351.pdf
https://peerj.com/articles/1351.pdf
Autor:
Ishaque M, Shaikh, Kuan-Boone, Tan, Anumita, Chaudhury, Yuanjie, Liu, Bee-Jen, Tan, Bernice M J, Tan, Gigi N C, Chiu
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 172(3)
Liposome co-encapsulation of synergistic anti-cancer drug combination is an emerging area that has demonstrated therapeutic benefit in clinical trials. Remote loading of two or more drugs into a single liposome constitutes a new challenge that calls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e9f2e715307231b2af26281215de7a7b
https://pubmed.ncbi.nlm.nih.gov/24459693
https://pubmed.ncbi.nlm.nih.gov/24459693
Autor:
Surajit Das, Gigi N.C. Chiu, Wai Kiong Ng, Anumita Chaudhury, Reginald B. H. Tan, Ronald F. S. Lee, Kuan-Boone Tan
Publikováno v:
International journal of pharmaceutics. 430(1-2)
The obstacles in translating liposome formulations into marketable products could be attributed to their physical instabilities upon long-term storage as aqueous dispersions. Lyophilization is the most commonly used technique to improve physical stab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5639240565ddb0ac7dc001659f243c88
https://pubmed.ncbi.nlm.nih.gov/22537806
https://pubmed.ncbi.nlm.nih.gov/22537806
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 160(2)
Prognosis of patients with acute myeloid leukemia (AML) remains poor despite the use of first-line induction chemotherapy. Therefore, it is imperative to find effective treatment for AML patients. Safingol is a bioactive sphingolipid which has demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868214170a8b567a5d3f448a2b7c181b
https://pubmed.ncbi.nlm.nih.gov/22100388
https://pubmed.ncbi.nlm.nih.gov/22100388
Publikováno v:
Oncology Letters.
Exploiting the sensitivity of cancer cells to reactive oxygen species (ROS) has been suggested as a strategy for the selective elimination of cancer cells. In this study, the ROS-generating sphingolipid safingol was combined with various conventional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333a6f455ade7ccba2872b757dbc5407
https://doi.org/10.3892/ol.2011.330
https://doi.org/10.3892/ol.2011.330
Autor:
Bee Jen Tan, Man-Yi Wong, Gigi N.C. Chiu, Kuan-Boone Tan, Leong-Uung Ling, Ishaque M. Shaikh, Anumita Chaudhury
Publikováno v:
Current drug metabolism. 10(8)
The use of drug cocktails has become a widely adopted strategy in clinical cancer therapy. Cytotoxic drug cocktails are often administered based on maximum tolerated dose (MTD) of each agent, with the belief of achieving maximum cell kill through tol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b56c110ad3acd5fc626d3d0bd064cf4
https://pubmed.ncbi.nlm.nih.gov/20214582
https://pubmed.ncbi.nlm.nih.gov/20214582
Publikováno v:
Blood. 116:3282-3282
Abstract 3282 The prognosis of patients with acute myeloid leukemia (AML) remains poor, despite the use of the first-line, anthracycline- and cytarabine-based induction chemotherapy aiming to induce complete remission in patients. Given the recent fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48f7dba153386b44ed4b2d224b8a3b96
https://doi.org/10.1182/blood.v116.21.3282.3282
https://doi.org/10.1182/blood.v116.21.3282.3282