Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kuai-lin Sun"'
Autor:
Ramya Visvanathan, Tadanobu Utsuki, Daniel E. Beck, Emma Lendy, Kuai-lin Sun, Yinghui Liu, Kirk W. Hering, Andrew Mesecar, Zhong-Yin Zhang, Karson S. Putt
Publikováno v:
SLAS Discovery, Vol 28, Iss 4, Pp 170-179 (2023)
A rare coding variant in PLCγ2 (P522R) expressed in microglia induces a mild activation of enzymatic activity when compared to wild-type. This mutation is reported to be protective against the cognitive decline associated with late-onset Alzheimer's
Externí odkaz:
https://doaj.org/article/2d760758ae3a4d61921580a59ddd5056
Autor:
Ramya Visvanathan, Tadanobu Utsuki, Daniel E Beck, W Brent Clayton, Emma Lendy, Kuai-Lin Sun, Yinghui Liu, Kirk W Hering, Andrew Mesecar, Zhong-Yin Zhang, Karson S Putt
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0299541 (2024)
The activities of the phospholipase C gamma (PLCγ) 1 and 2 enzymes are essential for numerous cellular processes. Unsurprisingly, dysregulation of PLCγ1 or PLCγ2 activity is associated with multiple maladies including immune disorders, cancers, an
Externí odkaz:
https://doaj.org/article/07330adcb09c40d7bd2c75877bb72103
Autor:
Daniel Beck, Brent Clayton, Steven Massey, Tadanobu Utsuki, Ramya Visvanathan, Kuai-lin Sun, Yinghui Liu, Kirk W. Hering, Zhong-Yin Zhang, Karson Putt
A Target Enabling Componentdescribing C16CF3C synthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128f0de658cfd06d7da764135bf65fc1
Autor:
Daniel Beck, Brent Clayton, Steven Massey, Tadanobu Utsuki, Ramya Visvanathan, Kuai-lin Sun, Yinghui Liu, Kirk W. Hering, Zhong-Yin Zhang, Karson Putt
A Target Enabling Component describing C8CF3C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0aeff7b4ee13896c49e4c159e6b2e1
Publikováno v:
ChemInform. 23
C 15 H 22 O 4 cristallise dans P2 1 avec a=13.525, b=7.549, c=13.646A, β=90.02°, Z=4, T=225K; affinement jusqu'a R=0.046. Dans ce compose, le cycle a sept chainons est fusionne de maniere cis au α-methylene-γ-lactone. La conformation du cyclohept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4296643adf5ea1c5864829c3b4cb0e9
https://doi.org/10.1002/chin.199216276
https://doi.org/10.1002/chin.199216276
Autor:
Steven R. Miller, Scott D. Larsen, Yuntao Song, David C. Boyles, Jeffrey A. Pfefferkorn, Chulho Choi, William Kissel, Bharat K. Trivedi, Daniel Merritt Bowles, Kuai Lin Sun
Publikováno v:
ChemInform. 38
This paper describes the development of an efficient and scalable second generation synthesis of novel, pyrrole-based HMG-CoA reductase inhibitors. Compound 1 was identified as part of a discovery program aimed at finding improved treatments for hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c135c7e5597e87adaacda948a6c81bb
https://doi.org/10.1002/chin.200748103
https://doi.org/10.1002/chin.200748103
Publikováno v:
ChemInform. 32
Reactions of α-amino acids with ketones under hydrogenation conditions using 20% Pd(OH) 2 /C as the catalyst gave N -mono-alkylated amino acids in high yields. Reductive methylation of N -mono-alkylated amino acids under the same hydrogenation condi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cf20b50fa6da2d17ccc5435d7a85f1c
https://doi.org/10.1002/chin.200103176
https://doi.org/10.1002/chin.200103176
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 48:211-213
C 15 H 22 O 4 cristallise dans P2 1 avec a=13.525, b=7.549, c=13.646A, β=90.02°, Z=4, T=225K; affinement jusqu'a R=0.046. Dans ce compose, le cycle a sept chainons est fusionne de maniere cis au α-methylene-γ-lactone. La conformation du cyclohept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::150becb6d31116c89d3e1374c0d9bc0a
https://doi.org/10.1107/s0108270191008867
https://doi.org/10.1107/s0108270191008867
Autor:
Samuel F. Victory, Michael Gaines, David C. Baker, M. P. Goncharenko, Frank Tagliaferri, Shijia Yan, Prashant P. Deshpande, Kuai-lin Sun, Steven A. Adah, Katherine Bauerdorf
Publikováno v:
Antiviral Research. 30:A40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d704063107bed25f50fd22d632d0f329
https://doi.org/10.1016/0166-3542(96)80301-9
https://doi.org/10.1016/0166-3542(96)80301-9