Structural heterogeneity of the microtubule lattice

Autor: Métivier, Mathieu, Gallaud, Emmanuel, Thomas, Alexandre, Pascal, Aude, Gagné, Jean-Philippe, Poirier, Guy, Chrétien, Denis, Gibeaux, Romain, Richard-Parpaillon, Laurent, Benaud, Christelle, Giet, Régis, Guyomar, Charlotte, Ku, Siou, Heumann, John, Bousquet, Clément, Guilloux, Gabriel, Gaillard, Natacha, Heichette, Claire, Duchesne, Laurence, Steinmetz, Michel

Microtubules are polymers assembled from αβ-tubulin heterodimers. They typically display lateral α-α and β-β homotypic interactions, except at one region, called the seam, where heterotypic α-β and β-α interactions occur. Here, we decorated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2755::c4f299b0c0df14c000d0f3b561b5e372
https://hal.archives-ouvertes.fr/hal-03428600

Study of GTP analog impacts on microtubule structure

Autor: Ku, Siou

Publikováno v: Biochimie, Biologie Moléculaire. Université de Rennes, 2021. Français. ⟨NNT : 2021REN1B023⟩

Microtubules are highly dynamic cytoskeletal fibers essential for the cell’s life. Their dynamics is intimately linked to the GTP hydrolysis of tubulin (β subunit) during polymerization. The metastable GDP-tubulin lattice is thought to be stabiliz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2755::d41dac6ae7cf24134bc2c4c7a6012efa
https://theses.hal.science/tel-03555243/document

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Determination of Microtubule Lattice Parameters from Cryo-electron Microscope Images Using TubuleJ.

Autor: Ku S; Univ Rennes, CNRS, IGDR (Institut de genetique et developpement de Rennes) - UMR 6290, F-35000 Rennes, France., Messaoudi C; Institut Curie, PSL Research University, CNRS UMS 2016, F-91401 Orsay, France.; Université Paris-Saclay, INSERM US43, F-91401 Orsay, France., Guyomar C; Univ Rennes, CNRS, IGDR (Institut de genetique et developpement de Rennes) - UMR 6290, F-35000 Rennes, France., Kervrann C; Inria-Centre de Rennes Bretagne Atlantique, Campus Universitaire de Beaulieu, 35042 Rennes, France., Chrétien D; Univ Rennes, CNRS, IGDR (Institut de genetique et developpement de Rennes) - UMR 6290, F-35000 Rennes, France.

Publikováno v: Bio-protocol [Bio Protoc] 2020 Nov 05; Vol. 10 (21), pp. e3814. Date of Electronic Publication: 2020 Nov 05 (Print Publication: 2020).